GB2321642B8 - Human telomerase reverse transcriptase promoter - Google Patents
Human telomerase reverse transcriptase promoterInfo
- Publication number
- GB2321642B8 GB2321642B8 GB9804859A GB9804859A GB2321642B8 GB 2321642 B8 GB2321642 B8 GB 2321642B8 GB 9804859 A GB9804859 A GB 9804859A GB 9804859 A GB9804859 A GB 9804859A GB 2321642 B8 GB2321642 B8 GB 2321642B8
- Authority
- GB
- United Kingdom
- Prior art keywords
- human telomerase
- reverse transcriptase
- telomerase reverse
- transcriptase promoter
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- C12N9/1241—Nucleotidyltransferases (2.7.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Zoology (AREA)
- Wood Science & Technology (AREA)
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- Endocrinology (AREA)
- Neurology (AREA)
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- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
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- Physics & Mathematics (AREA)
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- Hematology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72464396A | 1996-10-01 | 1996-10-01 | |
| US84441997A | 1997-04-18 | 1997-04-18 | |
| US84601797A | 1997-04-25 | 1997-04-25 | |
| US08/851,843 US6093809A (en) | 1996-10-01 | 1997-05-06 | Telomerase |
| US08/854,050 US6261836B1 (en) | 1996-10-01 | 1997-05-09 | Telomerase |
| US91131297A | 1997-08-14 | 1997-08-14 | |
| US91550397A | 1997-08-14 | 1997-08-14 | |
| US08/912,951 US6475789B1 (en) | 1996-10-01 | 1997-08-14 | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| GB9720890.4A GB2317891C (en) | 1996-10-01 | 1997-10-01 | Human Telomerase Catalytic Subunit |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| GB9804859D0 GB9804859D0 (en) | 1998-04-29 |
| GB2321642A GB2321642A (en) | 1998-08-05 |
| GB2321642B GB2321642B (en) | 2000-02-09 |
| GB2321642B8 true GB2321642B8 (en) | 2006-08-22 |
Family
ID=27575511
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9804859A Expired - Lifetime GB2321642B8 (en) | 1996-10-01 | 1997-10-01 | Human telomerase reverse transcriptase promoter |
| GB9720890.4A Expired - Lifetime GB2317891C (en) | 1996-10-01 | 1997-10-01 | Human Telomerase Catalytic Subunit |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB9720890.4A Expired - Lifetime GB2317891C (en) | 1996-10-01 | 1997-10-01 | Human Telomerase Catalytic Subunit |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US6166178A (enExample) |
| EP (6) | EP1333094B1 (enExample) |
| JP (7) | JP2001523947A (enExample) |
| KR (2) | KR20000048820A (enExample) |
| CN (3) | CN1254376A (enExample) |
| AT (3) | ATE552341T1 (enExample) |
| AU (2) | AU734089B2 (enExample) |
| BR (3) | BR9711844A (enExample) |
| CA (3) | CA2645721C (enExample) |
| DE (5) | DE69723531T3 (enExample) |
| EA (2) | EA199900349A1 (enExample) |
| ES (1) | ES2205132T5 (enExample) |
| FI (1) | FI990655A7 (enExample) |
| FR (1) | FR2757177A1 (enExample) |
| GB (2) | GB2321642B8 (enExample) |
| IL (2) | IL129103A0 (enExample) |
| NO (2) | NO319982B1 (enExample) |
| NZ (1) | NZ334709A (enExample) |
| SG (1) | SG94355A1 (enExample) |
| WO (2) | WO1998014592A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879609B2 (en) | 1996-10-01 | 2011-02-01 | Geron Corporation | Regulatory segments of the human gene for telomerase reverse transcriptase |
Families Citing this family (177)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958680A (en) | 1994-07-07 | 1999-09-28 | Geron Corporation | Mammalian telomerase |
| US6545133B1 (en) | 1995-08-04 | 2003-04-08 | Geron Corporation | Methods for purifying telomerase |
| US6517834B1 (en) | 1995-08-04 | 2003-02-11 | Geron Corporation | Purified telomerase |
| DE19681033D2 (de) | 1995-11-16 | 1999-03-18 | Michael W Dahm | Verfahren zur Quantifizierung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
| US6881571B1 (en) * | 1998-03-11 | 2005-04-19 | Exonhit Therapeutics S.A. | Qualitative differential screening |
| US6607898B1 (en) | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879609B2 (en) | 1996-10-01 | 2011-02-01 | Geron Corporation | Regulatory segments of the human gene for telomerase reverse transcriptase |
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Expiry date: 20170930 |