GB0124627D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GB0124627D0
GB0124627D0 GBGB0124627.1A GB0124627A GB0124627D0 GB 0124627 D0 GB0124627 D0 GB 0124627D0 GB 0124627 A GB0124627 A GB 0124627A GB 0124627 D0 GB0124627 D0 GB 0124627D0
Authority
GB
United Kingdom
Prior art keywords
novel compounds
solvate
salt
formula
provides compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0124627.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GBGB0124627.1A priority Critical patent/GB0124627D0/en
Publication of GB0124627D0 publication Critical patent/GB0124627D0/en
Priority to PL02370587A priority patent/PL370587A1/xx
Priority to IL16107402A priority patent/IL161074A0/xx
Priority to JP2003536220A priority patent/JP2005508966A/ja
Priority to CZ2004498A priority patent/CZ2004498A3/cs
Priority to AT02801692T priority patent/ATE356119T1/de
Priority to KR10-2004-7005546A priority patent/KR20040045833A/ko
Priority to PCT/US2002/032739 priority patent/WO2003033476A1/en
Priority to CA002463509A priority patent/CA2463509A1/en
Priority to PL02370138A priority patent/PL370138A1/xx
Priority to CNA028204522A priority patent/CN1571774A/zh
Priority to NZ531911A priority patent/NZ531911A/en
Priority to EP02801692A priority patent/EP1442025B1/en
Priority to JP2003536216A priority patent/JP2005510487A/ja
Priority to BR0213040-8A priority patent/BR0213040A/pt
Priority to CZ2004499A priority patent/CZ2004499A3/cs
Priority to DE60218721T priority patent/DE60218721T2/de
Priority to PCT/US2002/032740 priority patent/WO2003033480A1/en
Priority to DE60217147T priority patent/DE60217147T2/de
Priority to HU0402346A priority patent/HUP0402346A2/hu
Priority to IL16087202A priority patent/IL160872A0/xx
Priority to US10/492,641 priority patent/US7285557B2/en
Priority to KR1020047005548A priority patent/KR20050043724A/ko
Priority to RU2004110053/04A priority patent/RU2004110053A/ru
Priority to ES02801692T priority patent/ES2283647T3/es
Priority to US10/492,062 priority patent/US7220777B2/en
Priority to CA002463508A priority patent/CA2463508A1/en
Priority to HU0402335A priority patent/HUP0402335A3/hu
Priority to MXPA04003532A priority patent/MXPA04003532A/es
Priority to ES02801693T priority patent/ES2279009T3/es
Priority to AT02801693T priority patent/ATE349434T1/de
Priority to MXPA04003534A priority patent/MXPA04003534A/es
Priority to CNA028235932A priority patent/CN1596247A/zh
Priority to EP02801693A priority patent/EP1436267B1/en
Priority to BR0213242-7A priority patent/BR0213242A/pt
Priority to ZA200402672A priority patent/ZA200402672B/en
Priority to NO20041503A priority patent/NO20041503L/no
Priority to NO20041504A priority patent/NO20041504L/no
Priority to ZA200402814A priority patent/ZA200402814B/en
Priority to CO04034241A priority patent/CO5580779A2/es
Priority to CO04034243A priority patent/CO5580778A2/es
Priority to US11/466,530 priority patent/US20060287321A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/10—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D257/12—Six-membered rings having four nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
GBGB0124627.1A 2001-10-15 2001-10-15 Novel compounds Ceased GB0124627D0 (en)

Priority Applications (42)

Application Number Priority Date Filing Date Title
GBGB0124627.1A GB0124627D0 (en) 2001-10-15 2001-10-15 Novel compounds
BR0213242-7A BR0213242A (pt) 2001-10-15 2002-10-15 Composto ou um seu sal ou solvato, composto e seus sais de adição de ácido fisiologicamente aceitáveis, composição farmacêutica, método de tratamento de um ou mais distúrbios, uso de um composto, e, processo de preparação de um composto
IL16087202A IL160872A0 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
US10/492,641 US7285557B2 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
RU2004110053/04A RU2004110053A (ru) 2001-10-15 2002-10-15 Производные лактама в качестве антагонистов 11cby рецепторов человека
CZ2004498A CZ2004498A3 (cs) 2001-10-15 2002-10-15 Pyrimidinonové deriváty, způsob výroby a farmaceutický prostředek
AT02801692T ATE356119T1 (de) 2001-10-15 2002-10-15 Pyrimidinone als melanin concentrating hormone receptor 1
KR10-2004-7005546A KR20040045833A (ko) 2001-10-15 2002-10-15 사람 11ＣＢｙ 수용체에 대한 길항제로서의 락탐 유도체
PCT/US2002/032739 WO2003033476A1 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
CA002463509A CA2463509A1 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
PL02370138A PL370138A1 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
CNA028204522A CN1571774A (zh) 2001-10-15 2002-10-15 作为黑素浓缩激素受体1的嘧啶酮化合物
NZ531911A NZ531911A (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
EP02801692A EP1442025B1 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
JP2003536216A JP2005510487A (ja) 2001-10-15 2002-10-15 メラニン凝集ホルモン受容体１としてのピリミジノン類
BR0213040-8A BR0213040A (pt) 2001-10-15 2002-10-15 Composto, processo para preparar um composto, e, método de tratar doenças
CZ2004499A CZ2004499A3 (cs) 2001-10-15 2002-10-15 Laktamový derivátŹ způsob jeho výroby a farmaceutický prostředek
DE60218721T DE60218721T2 (de) 2001-10-15 2002-10-15 Pyrimidione als Melanin-konzentrierenden Hormonrezeptor 1
PCT/US2002/032740 WO2003033480A1 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
DE60217147T DE60217147T2 (de) 2001-10-15 2002-10-15 Lactamderivate zur verwendung als humane 11cby rezeptorantagonisten
HU0402346A HUP0402346A2 (hu) 2001-10-15 2002-10-15 Humán 11CBy receptor antagonista hatású laktámszármazékok, eljárás ezek előállítására és alkalmazásuk gyógyszerkészítmény előállítására
PL02370587A PL370587A1 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
KR1020047005548A KR20050043724A (ko) 2001-10-15 2002-10-15 멜라닌 농축 호르몬 수용체 1에 대한 피리미디논
IL16107402A IL161074A0 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
JP2003536220A JP2005508966A (ja) 2001-10-15 2002-10-15 ヒト１１ＣＢｙ受容体に対する拮抗薬としてのラクタム誘導体
ES02801692T ES2283647T3 (es) 2001-10-15 2002-10-15 Pirimidinonas como receptor 1 de la hormona de concentracion de la melanina.
US10/492,062 US7220777B2 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
CA002463508A CA2463508A1 (en) 2001-10-15 2002-10-15 Pyrimidinones as melanin concentrating hormone receptor 1
HU0402335A HUP0402335A3 (en) 2001-10-15 2002-10-15 Pyrimidinones condensated by a carbo- or heterocycle, process for their preparation and their use
MXPA04003532A MXPA04003532A (es) 2001-10-15 2002-10-15 Pirimidinonas como receptor 1 de la hormona concentradora de melanina.
ES02801693T ES2279009T3 (es) 2001-10-15 2002-10-15 Derivados de lactama como antagonistas de receptores 11cby humanos.
AT02801693T ATE349434T1 (de) 2001-10-15 2002-10-15 Lactamderivaten zur verwendung als humane 11cby rezeptorantagonisten
MXPA04003534A MXPA04003534A (es) 2001-10-15 2002-10-15 Derivados de lactam como antagonistas para receptores 11cby humanos.
CNA028235932A CN1596247A (zh) 2001-10-15 2002-10-15 用作人11cby受体拮抗剂的内酰胺衍生物
EP02801693A EP1436267B1 (en) 2001-10-15 2002-10-15 Lactam derivatives as antagonists for human 11cby receptors
ZA200402672A ZA200402672B (en) 2001-10-15 2004-04-05 Lactam derivatives as antagonists for human 11CBy receptors.
NO20041503A NO20041503L (no) 2001-10-15 2004-04-13 Pyrimidinoner som melanin konsentrerende hormon reseptor 1
NO20041504A NO20041504L (no) 2001-10-15 2004-04-13 Lactamderivater som antagonister for humane 11CBY reseptorer.
ZA200402814A ZA200402814B (en) 2001-10-15 2004-04-13 Pyrimidinones as melanin concentrating hormone receptor 1
CO04034241A CO5580779A2 (es) 2001-10-15 2004-04-14 Pirimidinonas como receptor 1 de la hormona concentradora de la melanina
CO04034243A CO5580778A2 (es) 2001-10-15 2004-04-14 Derivados de lactama como antagonistas para receptores 11cby humanos
US11/466,530 US20060287321A1 (en) 2001-10-15 2006-08-23 Novel Lactam Derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0124627.1A GB0124627D0 (en) 2001-10-15 2001-10-15 Novel compounds

Publications (1)

Publication Number Publication Date
GB0124627D0 true GB0124627D0 (en) 2001-12-05

Family

ID=9923785

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0124627.1A Ceased GB0124627D0 (en) 2001-10-15 2001-10-15 Novel compounds

Country Status (21)

Country Link
EP (2) EP1436267B1 (https=)
JP (2) JP2005510487A (https=)
KR (2) KR20040045833A (https=)
CN (2) CN1596247A (https=)
AT (2) ATE349434T1 (https=)
BR (2) BR0213242A (https=)
CA (2) CA2463509A1 (https=)
CO (2) CO5580779A2 (https=)
CZ (2) CZ2004499A3 (https=)
DE (2) DE60218721T2 (https=)
ES (2) ES2279009T3 (https=)
GB (1) GB0124627D0 (https=)
HU (2) HUP0402335A3 (https=)
IL (2) IL160872A0 (https=)
MX (2) MXPA04003532A (https=)
NO (2) NO20041504L (https=)
NZ (1) NZ531911A (https=)
PL (2) PL370587A1 (https=)
RU (1) RU2004110053A (https=)
WO (2) WO2003033480A1 (https=)
ZA (2) ZA200402672B (https=)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL161717A0 (en) 2001-11-26 2004-09-27 Schering Corp Piperidine-based mch antagonists for treatment of obesity and cns disorders
CA2468015A1 (en) 2001-11-27 2003-06-05 Merck & Co., Inc. 2-aminoquinoline compounds
DE10238865A1 (de) * 2002-08-24 2004-03-11 Boehringer Ingelheim International Gmbh Neue Carbonsäureamid-Verbindungen mit MCH-antagonistischer Wirkung, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US7351719B2 (en) 2002-10-31 2008-04-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20060194871A1 (en) * 2003-04-11 2006-08-31 Barvian Kevin K Heterocyclic mchr1 antagoists
CN100418965C (zh) * 2003-08-15 2008-09-17 万有制药株式会社 咪唑并吡啶衍生物
KR100747042B1 (ko) * 2003-08-19 2007-08-07 솔젠트 (주) 신물질６-메틸-３-펜에틸-３,４-디히드로-１ｈ-큐나졸린-２-티온,이의 제조방법 및 이를 유효성분으로 포함하는 미백 효능조성물
US20070078125A1 (en) * 2003-10-23 2007-04-05 Glaxo Group Limited Arylamine mch r1 antagonists
US7592373B2 (en) 2003-12-23 2009-09-22 Boehringer Ingelheim International Gmbh Amide compounds with MCH antagonistic activity and medicaments comprising these compounds
UA83416C2 (en) 2004-02-13 2008-07-10 Баниу Фармасьютикал Ко., Лтд. Fused ring 4-oxopyrimidine derivative
DE102004010893A1 (de) * 2004-03-06 2005-09-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
US7605176B2 (en) 2004-03-06 2009-10-20 Boehringer Ingelheim International Gmbh β-ketoamide compounds with MCH antagonistic activity
US20080125403A1 (en) 2004-04-02 2008-05-29 Merck & Co., Inc. Method of Treating Men with Metabolic and Anthropometric Disorders
DE102004017934A1 (de) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
US7524862B2 (en) 2004-04-14 2009-04-28 Boehringer Ingelheim International Gmbh Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
US7902356B2 (en) 2004-12-17 2011-03-08 Eli Lilly And Company Thiazolopyridinone derivates as MCH receptor antagonists
WO2006085692A1 (ja) * 2005-02-14 2006-08-17 Banyu Pharmaceutical Co., Ltd ４（３ｈ）－キナゾリノン誘導体の結晶
US7989445B2 (en) 2005-04-28 2011-08-02 Takeda Pharmaceutical Company Limited Thienopyrimidone compound
WO2007011286A1 (en) * 2005-07-15 2007-01-25 Astrazeneca Ab Therapeutic agents
KR20080042158A (ko) * 2005-08-31 2008-05-14 셀진 코포레이션 이소인돌-이미드 화합물과 이를 포함하는 조성물 및 이를이용한 방법
KR101384132B1 (ko) * 2005-10-19 2014-04-10 깃세이 야쿠힌 고교 가부시키가이샤 축합 복소환 유도체, 그것을 함유하는 의약 조성물 및 그의약 용도
US8618115B2 (en) * 2005-10-26 2013-12-31 Bristol-Myers Squibb Company Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
US7745447B2 (en) * 2005-10-26 2010-06-29 Bristol-Myers Squibb Company Substituted thieno[3,2-D]pyrimidines as non-basic melanin concentrating hormone receptor-1 antagonists
US8329704B2 (en) 2005-12-21 2012-12-11 Janssen Pharmaceutica, N.V. Substituted pyrazinone derivatives for use in MCH-1 mediated diseases
US7553836B2 (en) 2006-02-06 2009-06-30 Bristol-Myers Squibb Company Melanin concentrating hormone receptor-1 antagonists
EP1987020B1 (en) * 2006-02-15 2012-10-03 Sanofi Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
WO2007093365A2 (en) * 2006-02-15 2007-08-23 Sanofi-Aventis Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
KR20080094699A (ko) 2006-02-15 2008-10-23 사노피-아벤티스 신규 아미노알콜-치환된 아릴디하이드로이소퀴놀리논, 이의제조 방법 및 이의 약물로서의 용도
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