FR21C1018I2 - Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide - Google Patents

Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide

Info

Publication number
FR21C1018I2
FR21C1018I2 FR21C1018C FR21C1018C FR21C1018I2 FR 21C1018 I2 FR21C1018 I2 FR 21C1018I2 FR 21C1018 C FR21C1018 C FR 21C1018C FR 21C1018 C FR21C1018 C FR 21C1018C FR 21C1018 I2 FR21C1018 I2 FR 21C1018I2
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FR
France
Prior art keywords
difluorobenzo
cyclopropanecarboxamide
dioxol
dihydroxypropyl
methylpropane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR21C1018C
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English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Vertex Pharmaceuticals Inc
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43903962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR21C1018(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of FR21C1018I1 publication Critical patent/FR21C1018I1/fr
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Publication of FR21C1018I2 publication Critical patent/FR21C1018I2/fr
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
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    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
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FR21C1018C 2010-03-25 2021-05-14 Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide Active FR21C1018I2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US31737610P 2010-03-25 2010-03-25
US31995310P 2010-04-01 2010-04-01
US32156110P 2010-04-07 2010-04-07
US32163610P 2010-04-07 2010-04-07
PCT/US2011/030032 WO2011119984A1 (en) 2010-03-25 2011-03-25 Solid forms of (r)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihyderoxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide
EP11713134.2A EP2563778B1 (en) 2010-03-25 2011-03-25 Crystalline form of (r)-1(2,2 -difluorobenzo[d][1,3]dioxol-5yl)-n-(1-(2,3-dihyderoxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2yl)-1h-indol-5yl)cyclopropanecarboxamide

Publications (2)

Publication Number Publication Date
FR21C1018I1 FR21C1018I1 (fr) 2021-07-02
FR21C1018I2 true FR21C1018I2 (fr) 2023-02-17

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FR21C1018C Active FR21C1018I2 (fr) 2010-03-25 2021-05-14 Dispersion solide de la forme amorphe de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-méthylpropane-2-yl)-1h-indol-5-yl)-cyclopropanecarboxamide

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US (1) US20110251253A1 (enExample)
EP (5) EP2563778B1 (enExample)
JP (5) JP5734410B2 (enExample)
CN (3) CN106083832A (enExample)
AU (3) AU2011230508B2 (enExample)
BR (1) BR112012024338B1 (enExample)
CA (2) CA3016080C (enExample)
CY (3) CY1123794T1 (enExample)
DK (1) DK2826776T3 (enExample)
ES (4) ES2604105T3 (enExample)
FR (1) FR21C1018I2 (enExample)
HR (2) HRP20230661T1 (enExample)
HU (3) HUE062892T2 (enExample)
IL (4) IL222117B (enExample)
LT (2) LT2826776T (enExample)
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NZ (3) NZ700556A (enExample)
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