FR15C0047I1 - - Google Patents
Info
- Publication number
- FR15C0047I1 FR15C0047I1 FR15C0047C FR15C0047I1 FR 15C0047 I1 FR15C0047 I1 FR 15C0047I1 FR 15C0047 C FR15C0047 C FR 15C0047C FR 15C0047 I1 FR15C0047 I1 FR 15C0047I1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37307202P | 2002-04-16 | 2002-04-16 | |
PCT/US2003/011510 WO2003089428A1 (fr) | 2002-04-16 | 2003-04-14 | Antagonistes tricycliques du recepteur de thrombine |
Publications (2)
Publication Number | Publication Date |
---|---|
FR15C0047I1 true FR15C0047I1 (fr) | 2015-08-28 |
FR15C0047I2 FR15C0047I2 (fr) | 2016-05-06 |
Family
ID=29250954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR15C0047C Active FR15C0047I2 (fr) | 2002-04-16 | 2015-07-03 | Antagonistes tricycliques du recepteur de thrombine |
Country Status (34)
Country | Link |
---|---|
US (3) | US7304078B2 (fr) |
EP (5) | EP1860106B1 (fr) |
JP (2) | JP4558331B2 (fr) |
KR (1) | KR101026929B1 (fr) |
CN (1) | CN1659162B (fr) |
AR (1) | AR039570A1 (fr) |
AT (3) | ATE378330T1 (fr) |
AU (1) | AU2003221932B2 (fr) |
BR (1) | BRPI0309309B8 (fr) |
CA (1) | CA2482858C (fr) |
CY (3) | CY1107184T1 (fr) |
DE (3) | DE60331114D1 (fr) |
DK (2) | DK2065384T3 (fr) |
EC (1) | ECSP045368A (fr) |
ES (3) | ES2357876T3 (fr) |
FR (1) | FR15C0047I2 (fr) |
HK (3) | HK1070887A1 (fr) |
IL (1) | IL164585A (fr) |
LT (1) | LTC1495018I2 (fr) |
LU (1) | LU92759I2 (fr) |
MX (1) | MXPA04010308A (fr) |
MY (1) | MY144040A (fr) |
NL (1) | NL300746I2 (fr) |
NO (2) | NO330500B1 (fr) |
NZ (2) | NZ575139A (fr) |
PE (1) | PE20040412A1 (fr) |
PL (1) | PL214718B1 (fr) |
PT (2) | PT2065384E (fr) |
RU (2) | RU2329264C9 (fr) |
SG (1) | SG164279A1 (fr) |
SI (2) | SI1495018T1 (fr) |
TW (1) | TWI343919B (fr) |
WO (1) | WO2003089428A1 (fr) |
ZA (1) | ZA200408342B (fr) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6346510B1 (en) | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
US7235567B2 (en) * | 2000-06-15 | 2007-06-26 | Schering Corporation | Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist |
US7488742B2 (en) * | 2000-06-15 | 2009-02-10 | Schering Corporation | Thrombin receptor antagonists |
US20040192753A1 (en) * | 2000-06-15 | 2004-09-30 | Samuel Chackalamannil | Methods of use of thrombin receptor antagonists |
ATE406366T1 (de) * | 2004-05-28 | 2008-09-15 | Schering Corp | Gehinderte himbacinanaloga als thrombinrezeptorantagonisten |
CA2582353A1 (fr) * | 2004-10-06 | 2006-04-20 | University Of Rochester | Traitement de l'hypertension pulmonaire au moyen d'un agent inhibant une voie du facteur tissulaire |
PL2206697T3 (pl) * | 2005-01-14 | 2012-03-30 | Merck Sharp & Dohme | Egzo- oraz diastereoselektywna synteza analogów himbacyny |
US7541471B2 (en) * | 2005-01-14 | 2009-06-02 | Schering Corporation | Synthesis of himbacine analogs |
US7772276B2 (en) * | 2005-01-14 | 2010-08-10 | Schering Corporation | Exo-selective synthesis of himbacine analogs |
CN101137614A (zh) * | 2005-01-14 | 2008-03-05 | 先灵公司 | 喜巴辛类似物的手性炔丙醇和酯中间体的制备 |
WO2006076564A1 (fr) * | 2005-01-14 | 2006-07-20 | Schering Corporation | Synthese des analogues de l'himbacine |
KR20070116066A (ko) * | 2005-03-31 | 2007-12-06 | 쉐링 코포레이션 | 스피로사이클릭 트롬빈 수용체 길항제 |
WO2007075808A2 (fr) * | 2005-12-20 | 2007-07-05 | Schering Corporation | Procedes de prevention et/ou de traitement d’un trouble de proliferation de cellules |
EP1971336A2 (fr) * | 2005-12-22 | 2008-09-24 | Shering Corporation | Antagonistes de recepteur de thrombine en tant que phophylaxie aux complications de derivation cardiopulmonaire |
PE20080183A1 (es) * | 2006-04-06 | 2008-03-10 | Schering Corp | Terapias de combinacion de tra |
EP2266976B1 (fr) | 2006-04-13 | 2013-07-31 | Merck Sharp & Dohme Corp. | Antagonistes de récepteur de thrombine à cycle condensé |
AR061664A1 (es) * | 2006-06-29 | 2008-09-10 | Schering Corp | Derivados de himbacina como antagonistas del receptor de trombina biciclicos y triciclicos sustituidos. composiciones farmaceuticas. |
TWI367112B (en) * | 2006-06-30 | 2012-07-01 | Schering Corp | Immediate-release tablet formulations of a thrombin receptor antagonist |
AR061727A1 (es) * | 2006-06-30 | 2008-09-17 | Schering Corp | Sintesis de dietil [[ 5- ( 3-fluorofenil) -piridin -2il] metil] fosfonato |
DE102006036023A1 (de) | 2006-08-02 | 2008-02-07 | Sanofi-Aventis | Imino-imidazo-pyridinderivate mit antithrombotischer Aktivität |
TWI343262B (en) * | 2006-09-26 | 2011-06-11 | Schering Corp | Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist |
WO2008060372A2 (fr) * | 2006-10-04 | 2008-05-22 | Schering Corporation | Antagonistes du récepteur de la thrombine basés sur l'unité tricyclique modifiée de l'himbacine |
US8153664B2 (en) | 2006-10-04 | 2012-04-10 | Schering Corporation | Bicyclic and tricyclic derivatives as thrombin receptor antagonists |
WO2008079260A2 (fr) * | 2006-12-22 | 2008-07-03 | Schering Corporation | Promoteurs de désintégration dans des formulations de forme solide obtenues par un procédé de granulation par voie humide |
JP2010522169A (ja) * | 2007-03-23 | 2010-07-01 | シェーリング コーポレイション | トロンビン受容体アンタゴニストの使用による、経皮的インターベンション後の有害事象の低減 |
MY152040A (en) | 2008-02-05 | 2014-08-15 | Sanofi Aventis | Triazolopyridazines as par1 inhibitors, production thereof, and use as medicaments |
AU2009211888B2 (en) | 2008-02-05 | 2013-06-20 | Sanofi | Triazolium salts as PAR1 inhibitors, production thereof, and use as medicaments |
WO2009124103A2 (fr) * | 2008-04-02 | 2009-10-08 | Schering Corporation | Thérapies de combinaison comprenant des antagonistes de récepteur 1 activé par protéase (par1) associés à des antagonistes récepteur 4 activé par protéase (par4) |
EP2300435A2 (fr) | 2008-05-19 | 2011-03-30 | Schering Corporation | Composés hétérocycliques en tant qu`inhibiteurs du facteur ixa |
WO2010141525A1 (fr) * | 2009-06-04 | 2010-12-09 | Schering Corporation | Métabolite actif d'un antagoniste des récepteurs de la thrombine |
EP2440191A2 (fr) | 2009-06-08 | 2012-04-18 | Schering Corporation | Antagoniste du récepteur de la thrombine et comprimé de clopidogrel à dose fixe |
WO2011017296A1 (fr) | 2009-08-04 | 2011-02-10 | Schering Corporation | Dérivés de pyrimidine 4,5,6-trisubstituée comme inhibiteurs du facteur ixa |
WO2011128421A1 (fr) | 2010-04-16 | 2011-10-20 | Sanofi | Pyridyl-vinyl-pyrroles tricycliques utilisés comme inhibiteurs du par1 |
ES2527535T3 (es) | 2010-04-16 | 2015-01-26 | Sanofi | Piridil-vinil-pirazolo-quinolinas como inhibidores de PAR1 |
KR101303348B1 (ko) | 2010-06-25 | 2013-09-03 | 한국화학연구원 | 트롬빈 수용체 길항제인 [6+5]접합 바이사이클, 그의 제조방법 및 그를 포함하는 약제학적 조성물 |
US9340530B2 (en) | 2012-03-06 | 2016-05-17 | Merck Sharp & Dohme Corp. | Preparation and use of bicyclic himbacine derivatives as PAR-1 receptor antagonists |
EP3024550A4 (fr) * | 2013-07-22 | 2016-12-07 | Merck Sharp & Dohme | Co-cristal de l'antagoniste du récepteur par-1 de vorapaxar et aspirine |
EP3035928B1 (fr) * | 2013-08-22 | 2023-10-18 | Merck Sharp & Dohme LLC | Dérivés bicycliques de 3'-pyridyl substitué-6,6-difluoro himbacine |
WO2015026693A1 (fr) * | 2013-08-22 | 2015-02-26 | Merck Sharp & Dohme Corp. | Dérivés bicycliques de 7a-amide substitué-6,6-difluoro himbacine |
EP3035930A4 (fr) * | 2013-08-22 | 2017-03-08 | Merck Sharp & Dohme Corp. | Dérivés bicycliques de 7a-hétérocycle substitué-6,6-difluoro himbacine |
FR3014693B1 (fr) | 2013-12-16 | 2016-01-08 | Pf Medicament | Utilisation de la 3-(2-chloro-phenyl)-1-[4-(4-fluoro-benzyl)-piperazin-1-yl]-propenone pour la prevention et/ou le traitement des pathologies fonctionnelles pelvi-perineales |
US9969724B2 (en) | 2014-04-16 | 2018-05-15 | Merck Sharp & Dohme Corp. | Factor IXa inhibitors |
DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
CN105985303B (zh) * | 2015-02-13 | 2020-08-14 | 上海彩迩文生化科技有限公司 | 抗凝血剂的制备方法、中间体及其制备方法 |
CN106478608A (zh) * | 2015-09-01 | 2017-03-08 | 博瑞生物医药(苏州)股份有限公司 | 沃拉帕沙的硫酸盐的结晶多晶型物 |
CN106749201A (zh) * | 2015-11-25 | 2017-05-31 | 博瑞生物医药(苏州)股份有限公司 | 一种沃拉帕沙及其中间体的制备方法 |
WO2017134200A1 (fr) * | 2016-02-05 | 2017-08-10 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Nouvelle composition pharmaceutique à base de vorapaxar et de métoprolol |
TR201601548A2 (tr) * | 2016-02-05 | 2018-03-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Vorapaksar ve metoprololün bi̇r farmasöti̇k kompozi̇syonu |
CN107304200B (zh) * | 2016-04-22 | 2021-09-21 | 江苏天士力帝益药业有限公司 | 一种新的喜巴辛类似物及其在医药中的应用 |
CN106236779A (zh) * | 2016-08-22 | 2016-12-21 | 孔五 | 一种脐带血富血小板血浆prp的制备方法 |
FR3090317B1 (fr) | 2018-12-19 | 2021-05-07 | Cvasthera | Utilisation d’un antagoniste de par-1 pour le traitement d’une maladie inflammatoire chronique intestinale |
CN110407819B (zh) * | 2019-08-02 | 2020-06-26 | 牡丹江医学院 | 一种作为预防外科手术并发症的凝血酶受体拮抗剂 |
US20210113536A1 (en) * | 2019-10-21 | 2021-04-22 | United States Government as Represented by the Department of Veteran Affairs | Methods and compositions for detecting and treating venous thromboembolism |
FR3109089B1 (fr) | 2020-04-08 | 2023-04-14 | Cvasthera | Composition pharmaceutique pour le traitement des maladies inflammatoires intestinales |
JP2023534704A (ja) | 2020-07-22 | 2023-08-10 | ヤンセン ファーマシューティカ エヌ.ベー. | 第xia因子阻害剤として有用な化合物 |
US11814364B2 (en) | 2021-03-18 | 2023-11-14 | Janssen Pharmaceutica Nv | Pyridine N-oxide derivatives useful as factor XIa inhibitors |
US11919881B2 (en) | 2021-03-18 | 2024-03-05 | Janssen Pharmaceutica Nv | Substituted pyridine N-oxide derivatives useful as a factor XIa inhibitors |
US11845748B2 (en) | 2021-03-18 | 2023-12-19 | Janssen Pharmaceutica Nv | Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors |
EP4070658A1 (fr) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Utilisation de composés anticoagulants comme rodenticides |
US11897880B2 (en) | 2021-04-30 | 2024-02-13 | Janssen Pharmaceutica Nv | 7,8-dihydrobenzo[e]pyrido[3,4-c]azocine-2,5(3H,6H)-dione derivatives useful as a factor XIa inhibitors |
US11958856B2 (en) | 2021-07-22 | 2024-04-16 | Janssen Pharmaceutica Nv | Substituted 1,2,3,8,9,9a-hexahydro-5H-pyrrolo[1,2-a]azepin-5-ones as factor XIa inhibitors |
FR3134314A1 (fr) | 2022-04-08 | 2023-10-13 | Cvasthera | Composition pharmaceutique à base de vorapaxar et son utilisation pour le traitement des maladies inflammatoires intestinales |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2623810B2 (fr) | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
IL106197A (en) | 1992-07-30 | 1999-11-30 | Cor Therapeutics Inc | Agagonists for the rhombin receptors and pharmaceutical preparations containing them |
US5576328A (en) | 1994-01-31 | 1996-11-19 | Elf Sanofi | Method for the secondary prevention of ischemic events |
US6063847A (en) | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
PE133799A1 (es) * | 1997-11-25 | 2000-01-10 | Schering Corp | Antagonistas del receptor de trombina |
FR2779726B1 (fr) | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
US20040192753A1 (en) | 2000-06-15 | 2004-09-30 | Samuel Chackalamannil | Methods of use of thrombin receptor antagonists |
CA2410177C (fr) | 2000-06-15 | 2010-05-11 | Schering Corporation | Antagonistes du recepteur de la thrombine |
US7488742B2 (en) | 2000-06-15 | 2009-02-10 | Schering Corporation | Thrombin receptor antagonists |
MXPA04003610A (es) | 2001-10-18 | 2004-07-27 | Schering Corp | Analogos de himbacina como antagonistas del receptor de trombina. |
-
2003
- 2003-04-14 AT AT03718393T patent/ATE378330T1/de active
- 2003-04-14 PL PL373332A patent/PL214718B1/pl unknown
- 2003-04-14 SI SI200331110T patent/SI1495018T1/sl unknown
- 2003-04-14 SG SG200607217-7A patent/SG164279A1/en unknown
- 2003-04-14 MX MXPA04010308A patent/MXPA04010308A/es active IP Right Grant
- 2003-04-14 AT AT07016461T patent/ATE455774T1/de not_active IP Right Cessation
- 2003-04-14 SI SI200331969T patent/SI2065384T1/sl unknown
- 2003-04-14 PT PT09150995T patent/PT2065384E/pt unknown
- 2003-04-14 EP EP07016461A patent/EP1860106B1/fr not_active Expired - Lifetime
- 2003-04-14 DE DE60331114T patent/DE60331114D1/de not_active Expired - Lifetime
- 2003-04-14 DE DE60335679T patent/DE60335679D1/de not_active Expired - Lifetime
- 2003-04-14 NZ NZ575139A patent/NZ575139A/en not_active IP Right Cessation
- 2003-04-14 JP JP2003586149A patent/JP4558331B2/ja not_active Expired - Fee Related
- 2003-04-14 MY MYPI20031400A patent/MY144040A/en unknown
- 2003-04-14 ES ES09150995T patent/ES2357876T3/es not_active Expired - Lifetime
- 2003-04-14 EP EP09150996A patent/EP2062890B1/fr not_active Expired - Lifetime
- 2003-04-14 US US10/412,982 patent/US7304078B2/en active Active
- 2003-04-14 NZ NZ535880A patent/NZ535880A/en not_active IP Right Cessation
- 2003-04-14 DK DK09150995.0T patent/DK2065384T3/da active
- 2003-04-14 PT PT03718393T patent/PT1495018E/pt unknown
- 2003-04-14 PE PE2003000375A patent/PE20040412A1/es active IP Right Grant
- 2003-04-14 ES ES03718393T patent/ES2297150T7/es active Active
- 2003-04-14 DE DE60317493.0T patent/DE60317493T3/de not_active Expired - Lifetime
- 2003-04-14 WO PCT/US2003/011510 patent/WO2003089428A1/fr active Application Filing
- 2003-04-14 AR ARP030101302A patent/AR039570A1/es active IP Right Grant
- 2003-04-14 EP EP09150995A patent/EP2065384B1/fr not_active Expired - Lifetime
- 2003-04-14 CN CN038131129A patent/CN1659162B/zh not_active Expired - Fee Related
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- 2003-04-14 EP EP08012015A patent/EP1982984B1/fr not_active Expired - Lifetime
- 2003-04-14 EP EP03718393A patent/EP1495018B3/fr not_active Expired - Lifetime
- 2003-04-14 AT AT09150995T patent/ATE494284T1/de active
- 2003-04-14 ES ES07016461T patent/ES2338171T3/es not_active Expired - Lifetime
- 2003-04-14 RU RU2004133375/04A patent/RU2329264C9/ru active
- 2003-04-14 KR KR1020047016409A patent/KR101026929B1/ko active IP Right Grant
- 2003-04-14 AU AU2003221932A patent/AU2003221932B2/en not_active Ceased
- 2003-04-14 DK DK03718393T patent/DK1495018T3/da active
- 2003-04-14 CA CA2482858A patent/CA2482858C/fr not_active Expired - Lifetime
- 2003-04-15 TW TW092108648A patent/TWI343919B/zh not_active IP Right Cessation
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2004
- 2004-10-14 IL IL164585A patent/IL164585A/en active IP Right Grant
- 2004-10-14 ZA ZA200408342A patent/ZA200408342B/xx unknown
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- 2004-11-15 NO NO20044963A patent/NO330500B1/no not_active IP Right Cessation
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2005
- 2005-04-22 HK HK05103479A patent/HK1070887A1/xx not_active IP Right Cessation
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2007
- 2007-04-10 US US11/733,635 patent/US7713999B2/en not_active Expired - Lifetime
- 2007-07-06 US US11/774,358 patent/US20070270439A1/en not_active Abandoned
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2008
- 2008-02-07 CY CY20081100152T patent/CY1107184T1/el unknown
- 2008-02-21 RU RU2008106401/04A patent/RU2008106401A/ru not_active Application Discontinuation
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2009
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- 2009-09-14 HK HK09108388.4A patent/HK1129893A1/xx not_active IP Right Cessation
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2010
- 2010-03-05 JP JP2010049903A patent/JP2010132710A/ja not_active Withdrawn
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2011
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2015
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- 2015-07-01 LT LTPA2015027C patent/LTC1495018I2/lt unknown
- 2015-07-03 FR FR15C0047C patent/FR15C0047I2/fr active Active
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- 2015-07-10 CY CY2015029C patent/CY2015029I1/el unknown