FI923268A0 - 8-vinyl- och 8-etynylkinolonkarboxylsyror. - Google Patents

8-vinyl- och 8-etynylkinolonkarboxylsyror.

Info

Publication number
FI923268A0
FI923268A0 FI923268A FI923268A FI923268A0 FI 923268 A0 FI923268 A0 FI 923268A0 FI 923268 A FI923268 A FI 923268A FI 923268 A FI923268 A FI 923268A FI 923268 A0 FI923268 A0 FI 923268A0
Authority
FI
Finland
Prior art keywords
vinyl
ethynylkinolonkarboxylsyror
och
ethynyl
novel
Prior art date
Application number
FI923268A
Other languages
English (en)
Other versions
FI923268A (fi
FI103043B (fi
FI103043B1 (fi
Inventor
Uwe Petersen
Thomas Himmler
Thomas Schenke
Andreas Krebs
Klaus Grohe
Klaus-Dieter Bremm
Karl Georg Metzger
Rainer Endermann
Hans-Joachim Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI923268A0 publication Critical patent/FI923268A0/fi
Publication of FI923268A publication Critical patent/FI923268A/fi
Priority to FI970312A priority Critical patent/FI970312A0/fi
Application granted granted Critical
Publication of FI103043B publication Critical patent/FI103043B/fi
Publication of FI103043B1 publication Critical patent/FI103043B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Paints Or Removers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI923268A 1991-07-19 1992-07-16 Menetelmä uusien, terapeuttisesti käyttökelpoisten 8-vinyyli- ja 8-etynyylikinolonikarboksyylihappojohdannaisten valmistamiseksi sekä menetelmässä käyttökelpoiset välituotteet FI103043B1 (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI970312A FI970312A0 (fi) 1991-07-19 1997-01-24 8-halogeenikinoliinikarboksyylihappojohdannaiset

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4123918A DE4123918A1 (de) 1991-07-19 1991-07-19 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
DE4123918 1991-07-19

Publications (4)

Publication Number Publication Date
FI923268A0 true FI923268A0 (fi) 1992-07-16
FI923268A FI923268A (fi) 1993-01-20
FI103043B FI103043B (fi) 1999-04-15
FI103043B1 FI103043B1 (fi) 1999-04-15

Family

ID=6436512

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923268A FI103043B1 (fi) 1991-07-19 1992-07-16 Menetelmä uusien, terapeuttisesti käyttökelpoisten 8-vinyyli- ja 8-etynyylikinolonikarboksyylihappojohdannaisten valmistamiseksi sekä menetelmässä käyttökelpoiset välituotteet

Country Status (22)

Country Link
EP (1) EP0523512B1 (fi)
JP (1) JP3174405B2 (fi)
KR (1) KR100240608B1 (fi)
AT (1) ATE147733T1 (fi)
AU (1) AU658901B2 (fi)
CA (1) CA2073993A1 (fi)
CZ (1) CZ282037B6 (fi)
DE (2) DE4123918A1 (fi)
DK (1) DK0523512T3 (fi)
ES (1) ES2097835T3 (fi)
FI (1) FI103043B1 (fi)
GR (1) GR3022305T3 (fi)
HU (1) HU219910B (fi)
IE (1) IE80557B1 (fi)
IL (1) IL102520A (fi)
MX (1) MX9204110A (fi)
NO (1) NO302886B1 (fi)
PL (1) PL171910B1 (fi)
RU (1) RU2077533C1 (fi)
SK (1) SK219192A3 (fi)
TW (1) TW201309B (fi)
ZA (1) ZA925351B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4303657A1 (de) * 1993-02-09 1994-08-11 Bayer Ag Neue Chinolon- und Naphthyridoncarbonsäurederivate
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4425659A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Neue N1-diverse 6-Fluor-8-difluormethoxy substituierte Chinoloncarbonsäuren
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
WO1997040036A1 (fr) * 1996-04-19 1997-10-30 Wakunaga Pharmaceutical Co., Ltd. Nouveaux derives de l'acide pyridonocarboxylique ou des sels de cet acide et agents antibacteriens contenant ces substances en tant que composant actif
WO1998024781A1 (fr) * 1996-12-04 1998-06-11 Daiichi Pharmaceutical Co., Ltd. Derives d'aminomethylpyrrolidine substitue
SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
JP4639149B2 (ja) 2003-09-10 2011-02-23 杏林製薬株式会社 7−(4−置換−3−シクロプロピルアミノメチル−1−ピロリジニル)キノロンカルボン酸誘導体
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
EP1930321A4 (en) 2005-09-28 2011-04-27 Daiichi Sankyo Co Ltd PROCESS FOR THE SYNTHESIS OF 5-AZASPIRO [2.4] -HEPTANE TETRASUBSTITUTED DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF
CA2647454A1 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
BRPI0709772B8 (pt) 2006-03-28 2021-05-25 The Protecter & Gamble Company sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico
WO2008143343A1 (ja) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. 14位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
KR20210006401A (ko) * 2018-05-09 2021-01-18 바이엘 애니멀 헬스 게엠베하 신규한 퀴놀린 유도체
RU2757741C1 (ru) * 2021-03-01 2021-10-21 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Производное ципрофлоксацина, обладающее антибактериальной активностью в отношении антибиотикоустойчивых штаммов микроорганизмов

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123536A (en) * 1977-12-14 1978-10-31 Warner-Lambert Company Dialkyl ({[3-(alkoxycarbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)propanedioates
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US5047538A (en) * 1990-04-12 1991-09-10 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents

Also Published As

Publication number Publication date
ES2097835T3 (es) 1997-04-16
NO922639L (no) 1993-01-20
CZ219192A3 (en) 1993-02-17
NO922639D0 (no) 1992-07-03
FI923268A (fi) 1993-01-20
FI103043B (fi) 1999-04-15
IE80557B1 (en) 1998-09-23
CA2073993A1 (en) 1993-01-20
SK279221B6 (sk) 1998-08-05
AU1966392A (en) 1993-01-21
JP3174405B2 (ja) 2001-06-11
RU2077533C1 (ru) 1997-04-20
DK0523512T3 (da) 1997-06-30
DE4123918A1 (de) 1993-01-21
GR3022305T3 (en) 1997-04-30
IL102520A (en) 1997-07-13
IL102520A0 (en) 1993-01-14
JPH05262738A (ja) 1993-10-12
TW201309B (fi) 1993-03-01
SK219192A3 (en) 1998-08-05
IE922348A1 (en) 1993-01-27
ATE147733T1 (de) 1997-02-15
PL295331A1 (en) 1993-07-12
MX9204110A (es) 1993-08-01
ZA925351B (en) 1993-04-28
HUT61741A (en) 1993-03-01
EP0523512A1 (de) 1993-01-20
HU219910B (hu) 2001-09-28
EP0523512B1 (de) 1997-01-15
KR100240608B1 (ko) 2000-03-02
KR930002320A (ko) 1993-02-22
PL171910B1 (pl) 1997-06-30
DE59207880D1 (de) 1997-02-27
AU658901B2 (en) 1995-05-04
CZ282037B6 (cs) 1997-04-16
NO302886B1 (no) 1998-05-04
HU9202349D0 (en) 1992-10-28
FI103043B1 (fi) 1999-04-15

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FG Patent granted

Owner name: BAYER AKTIENGESELLSCHAFT