GR3022305T3 - 8-vinyl- and 8-ethinyl-quinolone carboxylic acids - Google Patents

8-vinyl- and 8-ethinyl-quinolone carboxylic acids

Info

Publication number
GR3022305T3
GR3022305T3 GR970400065T GR970400065T GR3022305T3 GR 3022305 T3 GR3022305 T3 GR 3022305T3 GR 970400065 T GR970400065 T GR 970400065T GR 970400065 T GR970400065 T GR 970400065T GR 3022305 T3 GR3022305 T3 GR 3022305T3
Authority
GR
Greece
Prior art keywords
vinyl
ethinyl
carboxylic acids
quinolone carboxylic
quinolone
Prior art date
Application number
GR970400065T
Other languages
English (en)
Inventor
Uwe Dr Petersen
Thomas Dr Himmler
Thomas Dr Schenke
Andreas Dr Krebs
Klaus Dr Grohe
Klaus Klaus-Dieter Dr Bremm
Karl Georg Dr Metzger
Rainer Dr Endermann
Hans-Joachim Dr Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of GR3022305T3 publication Critical patent/GR3022305T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Paints Or Removers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GR970400065T 1991-07-19 1997-01-16 8-vinyl- and 8-ethinyl-quinolone carboxylic acids GR3022305T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4123918A DE4123918A1 (de) 1991-07-19 1991-07-19 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren

Publications (1)

Publication Number Publication Date
GR3022305T3 true GR3022305T3 (en) 1997-04-30

Family

ID=6436512

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970400065T GR3022305T3 (en) 1991-07-19 1997-01-16 8-vinyl- and 8-ethinyl-quinolone carboxylic acids

Country Status (22)

Country Link
EP (1) EP0523512B1 (el)
JP (1) JP3174405B2 (el)
KR (1) KR100240608B1 (el)
AT (1) ATE147733T1 (el)
AU (1) AU658901B2 (el)
CA (1) CA2073993A1 (el)
CZ (1) CZ282037B6 (el)
DE (2) DE4123918A1 (el)
DK (1) DK0523512T3 (el)
ES (1) ES2097835T3 (el)
FI (1) FI103043B1 (el)
GR (1) GR3022305T3 (el)
HU (1) HU219910B (el)
IE (1) IE80557B1 (el)
IL (1) IL102520A (el)
MX (1) MX9204110A (el)
NO (1) NO302886B1 (el)
PL (1) PL171910B1 (el)
RU (1) RU2077533C1 (el)
SK (1) SK219192A3 (el)
TW (1) TW201309B (el)
ZA (1) ZA925351B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4303657A1 (de) * 1993-02-09 1994-08-11 Bayer Ag Neue Chinolon- und Naphthyridoncarbonsäurederivate
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4425659A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Neue N1-diverse 6-Fluor-8-difluormethoxy substituierte Chinoloncarbonsäuren
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
WO1997040036A1 (fr) * 1996-04-19 1997-10-30 Wakunaga Pharmaceutical Co., Ltd. Nouveaux derives de l'acide pyridonocarboxylique ou des sels de cet acide et agents antibacteriens contenant ces substances en tant que composant actif
WO1998024781A1 (fr) * 1996-12-04 1998-06-11 Daiichi Pharmaceutical Co., Ltd. Derives d'aminomethylpyrrolidine substitue
SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
JP4639149B2 (ja) 2003-09-10 2011-02-23 杏林製薬株式会社 ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
EP1930321A4 (en) 2005-09-28 2011-04-27 Daiichi Sankyo Co Ltd PROCESS FOR THE SYNTHESIS OF 5-AZASPIRO [2.4] -HEPTANE TETRASUBSTITUTED DERIVATIVES AND OPTICALLY ACTIVE INTERMEDIATES THEREOF
CA2647454A1 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
BRPI0709772B8 (pt) 2006-03-28 2021-05-25 The Protecter & Gamble Company sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico
WO2008143343A1 (ja) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
KR20210006401A (ko) * 2018-05-09 2021-01-18 바이엘 애니멀 헬스 게엠베하 신규한 퀴놀린 유도체
RU2757741C1 (ru) * 2021-03-01 2021-10-21 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Производное ципрофлоксацина, обладающее антибактериальной активностью в отношении антибиотикоустойчивых штаммов микроорганизмов

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123536A (en) * 1977-12-14 1978-10-31 Warner-Lambert Company Dialkyl ({[3-(alkoxycarbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)propanedioates
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US5047538A (en) * 1990-04-12 1991-09-10 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents

Also Published As

Publication number Publication date
FI923268A0 (fi) 1992-07-16
ES2097835T3 (es) 1997-04-16
NO922639L (no) 1993-01-20
CZ219192A3 (en) 1993-02-17
NO922639D0 (no) 1992-07-03
FI923268A (fi) 1993-01-20
FI103043B (fi) 1999-04-15
IE80557B1 (en) 1998-09-23
CA2073993A1 (en) 1993-01-20
SK279221B6 (sk) 1998-08-05
AU1966392A (en) 1993-01-21
JP3174405B2 (ja) 2001-06-11
RU2077533C1 (ru) 1997-04-20
DK0523512T3 (da) 1997-06-30
DE4123918A1 (de) 1993-01-21
IL102520A (en) 1997-07-13
IL102520A0 (en) 1993-01-14
JPH05262738A (ja) 1993-10-12
TW201309B (el) 1993-03-01
SK219192A3 (en) 1998-08-05
IE922348A1 (en) 1993-01-27
ATE147733T1 (de) 1997-02-15
PL295331A1 (en) 1993-07-12
MX9204110A (es) 1993-08-01
ZA925351B (en) 1993-04-28
HUT61741A (en) 1993-03-01
EP0523512A1 (de) 1993-01-20
HU219910B (hu) 2001-09-28
EP0523512B1 (de) 1997-01-15
KR100240608B1 (ko) 2000-03-02
KR930002320A (ko) 1993-02-22
PL171910B1 (pl) 1997-06-30
DE59207880D1 (de) 1997-02-27
AU658901B2 (en) 1995-05-04
CZ282037B6 (cs) 1997-04-16
NO302886B1 (no) 1998-05-04
HU9202349D0 (en) 1992-10-28
FI103043B1 (fi) 1999-04-15

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