NO922639L - 8-vinyl- og 8-etinyl-kinolonkarboksylsyrer - Google Patents

8-vinyl- og 8-etinyl-kinolonkarboksylsyrer

Info

Publication number
NO922639L
NO922639L NO92922639A NO922639A NO922639L NO 922639 L NO922639 L NO 922639L NO 92922639 A NO92922639 A NO 92922639A NO 922639 A NO922639 A NO 922639A NO 922639 L NO922639 L NO 922639L
Authority
NO
Norway
Prior art keywords
vinyl
acids
quinoloncarboxylic
ethinyl
ethynyl
Prior art date
Application number
NO92922639A
Other languages
English (en)
Other versions
NO922639D0 (no
NO302886B1 (no
Inventor
Uwe Petersen
Thomas Himmler
Thomas Schenke
Andreas Krebs
Klaus Grohe
Klaus-Dieter Bremm
Karl-Georg Metzger
Rainer Endermann
Hans-Joachim Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO922639D0 publication Critical patent/NO922639D0/no
Publication of NO922639L publication Critical patent/NO922639L/no
Publication of NO302886B1 publication Critical patent/NO302886B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
NO922639A 1991-07-19 1992-07-03 Kinolonkarboksylsyre-derivater med anti-bakteriell virkning, mellomprodukter for fremstilling derav, legemidler inneholdende forbindelsene samt forbindelsenes anvendelse ved fremstilling av legemidler NO302886B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4123918A DE4123918A1 (de) 1991-07-19 1991-07-19 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren

Publications (3)

Publication Number Publication Date
NO922639D0 NO922639D0 (no) 1992-07-03
NO922639L true NO922639L (no) 1993-01-20
NO302886B1 NO302886B1 (no) 1998-05-04

Family

ID=6436512

Family Applications (1)

Application Number Title Priority Date Filing Date
NO922639A NO302886B1 (no) 1991-07-19 1992-07-03 Kinolonkarboksylsyre-derivater med anti-bakteriell virkning, mellomprodukter for fremstilling derav, legemidler inneholdende forbindelsene samt forbindelsenes anvendelse ved fremstilling av legemidler

Country Status (22)

Country Link
EP (1) EP0523512B1 (no)
JP (1) JP3174405B2 (no)
KR (1) KR100240608B1 (no)
AT (1) ATE147733T1 (no)
AU (1) AU658901B2 (no)
CA (1) CA2073993A1 (no)
CZ (1) CZ282037B6 (no)
DE (2) DE4123918A1 (no)
DK (1) DK0523512T3 (no)
ES (1) ES2097835T3 (no)
FI (1) FI103043B (no)
GR (1) GR3022305T3 (no)
HU (1) HU219910B (no)
IE (1) IE80557B1 (no)
IL (1) IL102520A (no)
MX (1) MX9204110A (no)
NO (1) NO302886B1 (no)
PL (1) PL171910B1 (no)
RU (1) RU2077533C1 (no)
SK (1) SK279221B6 (no)
TW (1) TW201309B (no)
ZA (1) ZA925351B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4303657A1 (de) * 1993-02-09 1994-08-11 Bayer Ag Neue Chinolon- und Naphthyridoncarbonsäurederivate
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4425659A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Neue N1-diverse 6-Fluor-8-difluormethoxy substituierte Chinoloncarbonsäuren
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
US6211375B1 (en) 1996-04-19 2001-04-03 Wakunaga Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing the same as the active ingredient
WO1998024781A1 (fr) * 1996-12-04 1998-06-11 Daiichi Pharmaceutical Co., Ltd. Derives d'aminomethylpyrrolidine substitue
SK286420B6 (sk) 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
US7514451B2 (en) 2003-09-10 2009-04-07 Kyorin Pharmaceutical Co., Ltd. 7-(4-Substituted-3-cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
US7842818B2 (en) 2005-09-28 2010-11-30 Daiichi Sankyo Company, Limited Process for preparation of tetrasubstituted 5-azaspiro[2.4]- heptane derivatives and optically active intermediates thereof
KR101084521B1 (ko) 2006-03-28 2011-11-18 워너 칠콧 컴퍼니 엘엘씨 퀴놀론 중간체를 제조하기 위한 커플링 방법
JP5097967B2 (ja) 2006-03-28 2012-12-12 タイゲン バイオテクノロジー カンパニー,リミテッド リンゴ酸塩類、及び(3s,5s)−7−[3−アミノ−5−メチルーピペリジニル]−1−シクロプロピル−1,4−ジヒドロ−8−メトキシ−4−オキソ−3−キノリンカルボン酸の多形体類
CA2688008A1 (en) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position
BR112020022619A2 (pt) * 2018-05-09 2021-02-02 Bayer Animal Health Gmbh novos derivados de quinolina
RU2757741C1 (ru) * 2021-03-01 2021-10-21 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Производное ципрофлоксацина, обладающее антибактериальной активностью в отношении антибиотикоустойчивых штаммов микроорганизмов

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123536A (en) * 1977-12-14 1978-10-31 Warner-Lambert Company Dialkyl ({[3-(alkoxycarbonyl)-1,4-dihydro-4-oxo-8-quinolinyl]amino}methylene)propanedioates
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
US5047538A (en) * 1990-04-12 1991-09-10 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents

Also Published As

Publication number Publication date
ES2097835T3 (es) 1997-04-16
IE922348A1 (en) 1993-01-27
TW201309B (no) 1993-03-01
JP3174405B2 (ja) 2001-06-11
GR3022305T3 (en) 1997-04-30
JPH05262738A (ja) 1993-10-12
PL171910B1 (pl) 1997-06-30
FI103043B1 (fi) 1999-04-15
FI923268A0 (fi) 1992-07-16
HU9202349D0 (en) 1992-10-28
HU219910B (hu) 2001-09-28
DE59207880D1 (de) 1997-02-27
AU658901B2 (en) 1995-05-04
NO922639D0 (no) 1992-07-03
MX9204110A (es) 1993-08-01
IL102520A0 (en) 1993-01-14
CZ282037B6 (cs) 1997-04-16
SK219192A3 (en) 1998-08-05
HUT61741A (en) 1993-03-01
EP0523512B1 (de) 1997-01-15
DK0523512T3 (da) 1997-06-30
DE4123918A1 (de) 1993-01-21
AU1966392A (en) 1993-01-21
SK279221B6 (sk) 1998-08-05
FI103043B (fi) 1999-04-15
IE80557B1 (en) 1998-09-23
EP0523512A1 (de) 1993-01-20
CZ219192A3 (en) 1993-02-17
CA2073993A1 (en) 1993-01-20
RU2077533C1 (ru) 1997-04-20
NO302886B1 (no) 1998-05-04
KR930002320A (ko) 1993-02-22
PL295331A1 (en) 1993-07-12
ZA925351B (en) 1993-04-28
FI923268A (fi) 1993-01-20
ATE147733T1 (de) 1997-02-15
KR100240608B1 (ko) 2000-03-02
IL102520A (en) 1997-07-13

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Legal Events

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Free format text: LAPSED IN JANUARY 2003