FI873303A0 - Karbapenemderivat, foerfarande foer tillverkning av dessa och sammansaettningar innehaollande dessa. dessa. - Google Patents

Karbapenemderivat, foerfarande foer tillverkning av dessa och sammansaettningar innehaollande dessa. dessa.

Info

Publication number
FI873303A0
FI873303A0 FI873303A FI873303A FI873303A0 FI 873303 A0 FI873303 A0 FI 873303A0 FI 873303 A FI873303 A FI 873303A FI 873303 A FI873303 A FI 873303A FI 873303 A0 FI873303 A0 FI 873303A0
Authority
FI
Finland
Prior art keywords
group
dessa
alkyl
chem
hydroxy
Prior art date
Application number
FI873303A
Other languages
English (en)
Other versions
FI84826B (fi
FI873303A (fi
FI84826C (fi
Inventor
Tetsuo Miyadera
Yukio Sugimura
Toshihiko Hashimoto
Teruo Tanaka
Kimio Lino
Shinichi Sugawara
Tomoyuki Shibata
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56129648A external-priority patent/JPS5832879A/ja
Priority claimed from JP57081067A external-priority patent/JPS58198486A/ja
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI873303A publication Critical patent/FI873303A/fi
Publication of FI873303A0 publication Critical patent/FI873303A0/fi
Publication of FI84826B publication Critical patent/FI84826B/fi
Application granted granted Critical
Publication of FI84826C publication Critical patent/FI84826C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Control Of El Displays (AREA)
FI873303A 1981-08-19 1987-07-29 Foerfarande foer framstaellning av 6 -(1-hydroxietyl-2-substituerad-2-karbapenem-3-karboxylsyror anvaendbara som laekemedel. FI84826C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP12964881 1981-08-19
JP56129648A JPS5832879A (ja) 1981-08-19 1981-08-19 カルバペネム−３−カルボン酸誘導体およびその製法
JP8106782 1982-05-14
JP57081067A JPS58198486A (ja) 1982-05-14 1982-05-14 ペネムまたはカルバペネム−３−カルボン酸誘導体およびその製法
FI822864 1982-08-18
FI822864A FI76339C (fi) 1981-08-19 1982-08-18 Foerfarande foer framstaellning av som laekemedel anvaendbara 2-(1-imidoylpyrrolidin-3-yltio)-6-(1-hydroxietyl)-2- karbapenem-3-karboxylsyra och dess derivater.

Publications (4)

Publication Number Publication Date
FI873303A FI873303A (fi) 1987-07-29
FI873303A0 true FI873303A0 (fi) 1987-07-29
FI84826B FI84826B (fi) 1991-10-15
FI84826C FI84826C (fi) 1992-01-27

Family

ID=26422100

Family Applications (2)

Application Number Title Priority Date Filing Date
FI822864A FI76339C (fi) 1981-08-19 1982-08-18 Foerfarande foer framstaellning av som laekemedel anvaendbara 2-(1-imidoylpyrrolidin-3-yltio)-6-(1-hydroxietyl)-2- karbapenem-3-karboxylsyra och dess derivater.
FI873303A FI84826C (fi) 1981-08-19 1987-07-29 Foerfarande foer framstaellning av 6 -(1-hydroxietyl-2-substituerad-2-karbapenem-3-karboxylsyror anvaendbara som laekemedel.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI822864A FI76339C (fi) 1981-08-19 1982-08-18 Foerfarande foer framstaellning av som laekemedel anvaendbara 2-(1-imidoylpyrrolidin-3-yltio)-6-(1-hydroxietyl)-2- karbapenem-3-karboxylsyra och dess derivater.

Country Status (19)

Country Link
US (2) US4552873A (fi)
EP (2) EP0072710B1 (fi)
KR (1) KR890001426B1 (fi)
AT (2) ATE42952T1 (fi)
AU (2) AU563447B2 (fi)
CA (1) CA1214462A (fi)
CH (1) CH657853A5 (fi)
DE (2) DE3269183D1 (fi)
DK (2) DK169820B1 (fi)
ES (1) ES8400444A1 (fi)
FI (2) FI76339C (fi)
FR (1) FR2511678B1 (fi)
GB (2) GB2104075B (fi)
HU (1) HU189171B (fi)
IE (2) IE53736B1 (fi)
IT (1) IT1156491B (fi)
NO (2) NO159656C (fi)
NZ (1) NZ201633A (fi)
PH (1) PH20772A (fi)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997936A (en) * 1977-10-19 1991-03-05 Merck & Co., Inc. 2-carbamimidoyl-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
US5071843A (en) * 1978-07-24 1991-12-10 Merck & Co., Inc. Combination of 2-substituted carbapenems with dipeptidase inhibitors
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
US4710568A (en) * 1982-04-09 1987-12-01 Bristol-Myers Company Carbapenem antibiotics
US4642341A (en) * 1982-04-09 1987-02-10 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
US4665170A (en) * 1982-06-18 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
US4640799A (en) * 1982-06-18 1987-02-03 Bristol-Myers Company Carbapenem antibiotics
US4644061A (en) * 1982-09-28 1987-02-17 Bristol-Myers Company Carbapenem antibiotics
US4732977A (en) * 1982-09-28 1988-03-22 Bristol Myers Company Carbapenem antibiotics
NZ205626A (en) * 1982-09-28 1986-12-05 Bristol Myers Co Carbapenem antibiotics
US4746736A (en) * 1982-09-28 1988-05-24 Bristol-Myers Company Carbapenem antibiotics
DK140584A (da) * 1983-03-08 1984-09-09 Bristol Myers Co Fremgangsmaade til fremstilling af carbapenemderivater
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
US4717728A (en) * 1983-11-21 1988-01-05 Merck & Co., Inc. Cyclic amidinyl and cyclic guanidinyl thio carbapenems
US4992542A (en) * 1984-01-24 1991-02-12 Merck & Co., Inc. 2-substituted-6-carbadethiapen-2-em-3-carboxylic acids
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd １―置換カルバペネム―３―カルボン酸誘導体
US4696923A (en) * 1984-04-23 1987-09-29 Merck & Co., Inc. 6-[1-hydroxyethyl]-2-SR8 -1-methyl-1-carbadethiapen-2-em-3-carboxylic acids
DK270685A (da) * 1984-06-29 1985-12-30 Hoffmann La Roche Carbapenemderivater
US4820817A (en) * 1984-09-10 1989-04-11 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicycl(3.2.0)-hept-2-ene-2-carboxylic acid
US4757066A (en) * 1984-10-15 1988-07-12 Sankyo Company Limited Composition containing a penem or carbapenem antibiotic and the use of the same
CA1281720C (en) * 1984-11-08 1991-03-19 Makoto Sunagawa Carbapenem compounds and production thereof
JPS61275279A (ja) * 1984-12-25 1986-12-05 Sankyo Co Ltd カルバペネム化合物
PH24782A (en) * 1985-10-24 1990-10-30 Sankyo Co Composition containing a penem or carbapenem antibiotic and the use of the same
DE3780344T2 (de) * 1986-03-27 1993-01-28 Sumitomo Pharma Beta-lactam-verbindungen und deren herstellung.
KR880006244A (ko) * 1986-11-24 1988-07-22 후지사와 도모 기찌 로 3-피롤리디닐티오-1-아자바이스클로[3.2.0]햅트2-엔-2-카르복실산 화합물 및 이의 제조방법
EP0272455B1 (en) * 1986-11-24 1993-02-10 Fujisawa Pharmaceutical Co., Ltd. 3-Pyrrolidinylthio-1-azabicyclo [3.2.0] hept-2-ene-2-carboxylic acid compounds
US4866171A (en) * 1987-04-11 1989-09-12 Lederle (Japan), Ltd. (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazolium-6-yl)]thio-6-[R-1-hydroxyethyl]-1-methyl-carbapenum-3-carboxylate
JPS6425779A (en) * 1987-04-11 1989-01-27 Lederle Japan Ltd (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative
GB8804058D0 (en) * 1988-02-22 1988-03-23 Fujisawa Pharmaceutical Co 3-alkenyl-1-azabicyclo(3 2 0)hept-2-ene-2-carboxylic acid compounds
US4925838A (en) * 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
IE66711B1 (en) * 1988-04-01 1996-01-24 Sankyo Co 2-(heterocyclylthio) carbapenem derivatives their preparation and their use as antibiotics
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
GB8811237D0 (en) * 1988-05-12 1988-06-15 Fujisawa Pharmaceutical Co 3-pyrrolidinylthio-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives
US4963544A (en) * 1988-05-23 1990-10-16 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
US5102877A (en) * 1989-04-28 1992-04-07 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
GB8923844D0 (en) * 1989-10-23 1989-12-13 Fujisawa Pharmaceutical Co Carbapenem compounds
NO178498C (no) * 1990-02-23 1996-04-10 Sankyo Co Analogifremgangsmåte ved fremstilling av terapeutisk aktive karbapenemderivater
CA2036960A1 (en) * 1990-02-26 1991-08-27 Thomas A. Rano Novel synthesis of carbapenem intermediates
AU644008B2 (en) * 1990-08-10 1993-12-02 Sumitomo Pharmaceuticals Company, Limited Beta-lactam compounds, and their production and use
US5286721A (en) * 1990-10-15 1994-02-15 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
US5116833A (en) * 1990-10-19 1992-05-26 Bristol-Myers Squibb Company Antibiotic c-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
JPH05236980A (ja) * 1991-12-17 1993-09-17 Sankyo Co Ltd トランス−４−ヒドロキシ−ｌ−プロリンの製造法
GB9210096D0 (en) * 1992-05-11 1992-06-24 Fujisawa Pharmaceutical Co 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives and their preparation
AU5717894A (en) * 1992-12-21 1994-07-19 Chong Kun Dang Corporation 2-(2-substituted pyrrolidin-4-yl)thio-carbapenem derivatives
US5602118A (en) * 1993-03-16 1997-02-11 American Cyanamid Company 2-thiosubstituted carbapenems
WO1996026939A1 (en) * 1995-03-02 1996-09-06 Takeda Chemical Industries, Ltd. Carbapenem compounds, their production and use
KR100599876B1 (ko) * 2004-08-31 2006-07-13 한국화학연구원 2-아릴메틸아제티딘 카바페넴 유도체 및 그의 제조방법
KR100975907B1 (ko) * 2008-03-12 2010-08-13 (주)하이텍팜 입체선택적 3-아세틸티오-1-(아세트이미도일)피롤리딘유도체의 제조방법
KR101028689B1 (ko) * 2008-03-12 2011-04-14 (주)하이텍팜 신규한 결정성 3-머캅토-1-(아세트이미도일)피롤리딘유도체 및 그의 제조방법
US8841444B2 (en) 2008-07-30 2014-09-23 Ranbaxy Laboratories Limited Process for the preparation of carbapenem compounds
WO2011048583A1 (en) 2009-10-23 2011-04-28 Ranbaxy Laboratories Limited Process for the preparation of carbapenem compounds
KR100948403B1 (ko) * 2010-01-11 2010-03-19 (주) 대진유압기계 파이프 피팅 및 이에 이용되는 피팅용링 제조방법
CN101885727A (zh) * 2010-07-02 2010-11-17 深圳市海滨制药有限公司 一种制备帕尼培南的方法
WO2023235456A1 (en) * 2022-06-01 2023-12-07 The Johns Hopkins University Penem antibacterials against mycobacterial pathogens and d,d- and l,d transpeptidases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
US4189493A (en) * 1977-12-28 1980-02-19 Merck & Co., Inc. N-heterocyclic derivatives of thienamycin
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
DE3070269D1 (en) * 1979-08-10 1985-04-18 Beecham Group Plc Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation
JPS56122379A (en) * 1980-03-03 1981-09-25 Sankyo Co Ltd 1-carba-2-penem-3-carboxylic acid derivative
US4309346A (en) * 1980-03-27 1982-01-05 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via trithioorthoacetates
DE3169321D1 (en) * 1980-03-27 1985-04-25 Merck & Co Inc Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
JPS56156281A (en) * 1980-05-06 1981-12-02 Sanraku Inc Production of beta-lactam compound
JPS56161393A (en) * 1980-05-16 1981-12-11 Sanraku Inc Beta-lactam compound
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them

Also Published As

Publication number Publication date
DK170073B1 (da) 1995-05-15
NO167918C (no) 1991-12-27
AU563447B2 (en) 1987-07-09
EP0165384A1 (en) 1985-12-27
NO167918B (no) 1991-09-16
GB8518818D0 (en) 1985-08-29
CH657853A5 (de) 1986-09-30
ES515098A0 (es) 1983-10-16
NO875188L (no) 1983-02-21
IT1156491B (it) 1987-02-04
DE3279683D1 (en) 1989-06-15
AU8720782A (en) 1983-02-24
DE3269183D1 (en) 1986-03-27
IE862673L (en) 1983-02-19
FR2511678B1 (fr) 1986-04-25
US4552873A (en) 1985-11-12
FI84826B (fi) 1991-10-15
FI76339B (fi) 1988-06-30
FI873303A (fi) 1987-07-29
USRE34960E (en) 1995-05-30
PH20772A (en) 1987-04-10
GB2163156A (en) 1986-02-19
KR890001426B1 (ko) 1989-05-03
FI822864L (fi) 1983-02-20
NO822793L (no) 1983-02-21
DK40094A (da) 1994-04-07
GB2104075B (en) 1986-05-29
GB2104075A (en) 1983-03-02
EP0072710A1 (en) 1983-02-23
EP0165384B1 (en) 1989-05-10
HU189171B (en) 1986-06-30
IE821990L (en) 1983-02-19
KR840001174A (ko) 1984-03-28
ATE18048T1 (de) 1986-03-15
FI822864A0 (fi) 1982-08-18
IE53737B1 (en) 1989-02-01
IT8268024A0 (it) 1982-08-19
CA1214462A (en) 1986-11-25
IE53736B1 (en) 1989-02-01
GB2163156B (en) 1986-07-16
FI84826C (fi) 1992-01-27
DK370682A (da) 1983-02-20
NO875188D0 (no) 1987-12-14
NO159656B (no) 1988-10-17
ATE42952T1 (de) 1989-05-15
DK169820B1 (da) 1995-03-06
NO159656C (no) 1989-01-25
ES8400444A1 (es) 1983-10-16
FR2511678A1 (fr) 1983-02-25
AU582480B2 (en) 1989-03-23
FI76339C (fi) 1988-10-10
NZ201633A (en) 1985-11-08
EP0072710B1 (en) 1986-02-19
AU6513286A (en) 1987-02-19

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Owner name: SANKYO COMPANY LIMITED