JPS56156281A - Production of beta-lactam compound - Google Patents

Production of beta-lactam compound

Info

Publication number
JPS56156281A
JPS56156281A JP5860580A JP5860580A JPS56156281A JP S56156281 A JPS56156281 A JP S56156281A JP 5860580 A JP5860580 A JP 5860580A JP 5860580 A JP5860580 A JP 5860580A JP S56156281 A JPS56156281 A JP S56156281A
Authority
JP
Japan
Prior art keywords
formula
lactam
compound
thiol
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5860580A
Other languages
Japanese (ja)
Other versions
JPS6345393B2 (en
Inventor
Takeo Yoshioka
Kenichi Yamamoto
Yasuyuki Kato
Yasutaka Shimauchi
Tomoyuki Ishikura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Inc, Sanraku Ocean Co Ltd filed Critical Sanraku Inc
Priority to JP5860580A priority Critical patent/JPS56156281A/en
Publication of JPS56156281A publication Critical patent/JPS56156281A/en
Publication of JPS6345393B2 publication Critical patent/JPS6345393B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PURPOSE: Specific β-lactam compounds including novel ones is made to react with a thiol to produce β-lactam compounds or their salts which are used as an antibacterial.
CONSTITUTION: A compound of formula I (R1 is H, methyl, hydroxyl; R2 and R3 are H, alkyl, H-protecting group; R4 is H, ester residual group; n is 0, 1) or its salt reacts with a thiol of R5-SH (R5 is H, monovalent organic group) or its reactive derivative to affords a lactam compound of formula II or its salt such as 3-(2- acetamide-ethylthio)-6-isopropyl-7-oxo-1-azabicyclo[3,2,0]hepto-2-ene-2-carboxylic benzyl ester. Some of compounds of formula I are novel and antibiotics obtained by fermentation of a microorganism such as Streptomyces cattleya (NRRL 8057).
COPYRIGHT: (C)1981,JPO&Japio
JP5860580A 1980-05-06 1980-05-06 Production of beta-lactam compound Granted JPS56156281A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5860580A JPS56156281A (en) 1980-05-06 1980-05-06 Production of beta-lactam compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5860580A JPS56156281A (en) 1980-05-06 1980-05-06 Production of beta-lactam compound

Publications (2)

Publication Number Publication Date
JPS56156281A true JPS56156281A (en) 1981-12-02
JPS6345393B2 JPS6345393B2 (en) 1988-09-09

Family

ID=13089141

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5860580A Granted JPS56156281A (en) 1980-05-06 1980-05-06 Production of beta-lactam compound

Country Status (1)

Country Link
JP (1) JPS56156281A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58157788A (en) * 1982-03-16 1983-09-19 Sankyo Co Ltd Preparation of beta-lactam compound
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
USRE34960E (en) * 1981-08-19 1995-05-30 Sankyo Company, Limited Carbapenem compounds, and compositions containing them
JPS58157788A (en) * 1982-03-16 1983-09-19 Sankyo Co Ltd Preparation of beta-lactam compound
JPH039115B2 (en) * 1982-03-16 1991-02-07 Sankyo Co

Also Published As

Publication number Publication date
JPS6345393B2 (en) 1988-09-09

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