JPS5562088A - Novel beta-lactam derivative and its intermediate - Google Patents

Novel beta-lactam derivative and its intermediate

Info

Publication number
JPS5562088A
JPS5562088A JP13377378A JP13377378A JPS5562088A JP S5562088 A JPS5562088 A JP S5562088A JP 13377378 A JP13377378 A JP 13377378A JP 13377378 A JP13377378 A JP 13377378A JP S5562088 A JPS5562088 A JP S5562088A
Authority
JP
Japan
Prior art keywords
compound
antibacterial
agent
effective
lactam derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13377378A
Other languages
Japanese (ja)
Other versions
JPS6320830B2 (en
Inventor
Takeo Yoshioka
Kenichi Yamamoto
Kaoru Yamada
Yasuyuki Kato
Yasutaka Shimauchi
Tomoyuki Ishikura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Inc, Sanraku Ocean Co Ltd filed Critical Sanraku Inc
Priority to JP13377378A priority Critical patent/JPS5562088A/en
Priority to DE7979104192T priority patent/DE2965394D1/en
Priority to EP79104192A priority patent/EP0011173B1/en
Priority to CA000338878A priority patent/CA1142867A/en
Priority to US06/147,146 priority patent/US4337199A/en
Publication of JPS5562088A publication Critical patent/JPS5562088A/en
Priority to CA383,283A priority patent/CA1134298A/en
Publication of JPS6320830B2 publication Critical patent/JPS6320830B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A compound of formula I (R1 is H or methyl; R2 is substituted or nonsubstituted hydrocarbon group).
EXAMPLE: 2-(2-Acetamidoethylsulfynyl)6-ethyl-1-carba-2-penem-3-carboxylic acid benzyl ester.
USE: Effective component of an antibacterial agent or an antibacterial effect promoting agent. Synthetic intermediate of a highly effective antibacterial agent. A part of the objective compounds are effective to promote the antibacterial activity of β- lactam antibiotic substance to β-lactamase-producing resistant bacteria.
PROCESS: The compound I is prepared by reacting a compound II (R'2 is H or R2; when R1 is H, R2' is R2) orits salt with amild oxidizing agent which is substantially unreactive with the 1-carbo-2-pehem-3-caroxylic acid skeleton (e.g. m-chloroperbenzoic acid), in a solvent such as methylene chloride, at -30W+20°C.
COPYRIGHT: (C)1980,JPO&Japio
JP13377378A 1978-11-01 1978-11-01 Novel beta-lactam derivative and its intermediate Granted JPS5562088A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP13377378A JPS5562088A (en) 1978-11-01 1978-11-01 Novel beta-lactam derivative and its intermediate
DE7979104192T DE2965394D1 (en) 1978-11-01 1979-10-29 Process for producing antibiotic beta-lactam compounds
EP79104192A EP0011173B1 (en) 1978-11-01 1979-10-29 Process for producing antibiotic beta-lactam compounds
CA000338878A CA1142867A (en) 1978-11-01 1979-10-31 ANTIBIOTIC .beta.-LACTAM COMPOUNDS, PRODUCTION THEREOF, AND ITS USE AS ANTIMICROBIAL AGENT
US06/147,146 US4337199A (en) 1978-11-01 1980-05-06 Antibiotic β-lactam compounds, production thereof, and their use as antimicrobial agent
CA383,283A CA1134298A (en) 1978-11-01 1981-08-05 ANTIBIOTIC .beta.-LACTAM COMPOUNDS, PRODUCTION THEREOF, AND ITS USE AS ANTIMICROBIAL AGENTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13377378A JPS5562088A (en) 1978-11-01 1978-11-01 Novel beta-lactam derivative and its intermediate

Publications (2)

Publication Number Publication Date
JPS5562088A true JPS5562088A (en) 1980-05-10
JPS6320830B2 JPS6320830B2 (en) 1988-04-30

Family

ID=15112629

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13377378A Granted JPS5562088A (en) 1978-11-01 1978-11-01 Novel beta-lactam derivative and its intermediate

Country Status (1)

Country Link
JP (1) JPS5562088A (en)

Also Published As

Publication number Publication date
JPS6320830B2 (en) 1988-04-30

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