JPS5640687A - Preparation of penicillanic acid derivative or its salt - Google Patents

Preparation of penicillanic acid derivative or its salt

Info

Publication number
JPS5640687A
JPS5640687A JP11610879A JP11610879A JPS5640687A JP S5640687 A JPS5640687 A JP S5640687A JP 11610879 A JP11610879 A JP 11610879A JP 11610879 A JP11610879 A JP 11610879A JP S5640687 A JPS5640687 A JP S5640687A
Authority
JP
Japan
Prior art keywords
formula
acid
salt
penicillanic acid
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11610879A
Other languages
Japanese (ja)
Inventor
Nobuhiro Oi
Bunya Aoki
Teizo Shinozaki
Kanji Moro
Isao Matsunaga
Takao Nofuji
Toshiyuki Nehashi
Yusuke Harada
Hisao Endo
Takao Kimura
Hiroshi Okazaki
Haruki Ogawa
Minoru Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP11610879A priority Critical patent/JPS5640687A/en
Publication of JPS5640687A publication Critical patent/JPS5640687A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:A penicillanic acid derivative of formula I (R1 is H or lower alkyl; R2 is H or OH; R3 are 2W3 OH or lower alkanoyloxy groups, at least two of which are adjacent; when R1 is lower alkyl and R3 is OH, the substitution position of R3 is 3W5 position, and otherwise, it is 2W6 position.) or its salt, and a substituted ureidophenylacetic acid of formula II.
EXAMPLE: 6-[ D(-)-α-[ 3-( 2,3-dihydroxybenzoyl )-1-ureido ]-α-phenylacetamido ] penicillanic acid.
USE: An antibacterial agent and its intermediate, effective remarkably to the bacteria belonging to Pseudomonas genus.
PROCESS: The compound of formula I can be prepared, e.g. by reacting an α-aminophenyl-acetic acid with a benzoyl isocyanate and further reacting the resulting compound of formula II with 6-aminopenicillanic acid or its reactive derivative.
COPYRIGHT: (C)1981,JPO&Japio
JP11610879A 1979-09-12 1979-09-12 Preparation of penicillanic acid derivative or its salt Pending JPS5640687A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11610879A JPS5640687A (en) 1979-09-12 1979-09-12 Preparation of penicillanic acid derivative or its salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11610879A JPS5640687A (en) 1979-09-12 1979-09-12 Preparation of penicillanic acid derivative or its salt

Publications (1)

Publication Number Publication Date
JPS5640687A true JPS5640687A (en) 1981-04-16

Family

ID=14678883

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11610879A Pending JPS5640687A (en) 1979-09-12 1979-09-12 Preparation of penicillanic acid derivative or its salt

Country Status (1)

Country Link
JP (1) JPS5640687A (en)

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