JPS5659782A - Production of novel cephalosporin derivative - Google Patents

Production of novel cephalosporin derivative

Info

Publication number
JPS5659782A
JPS5659782A JP13489279A JP13489279A JPS5659782A JP S5659782 A JPS5659782 A JP S5659782A JP 13489279 A JP13489279 A JP 13489279A JP 13489279 A JP13489279 A JP 13489279A JP S5659782 A JPS5659782 A JP S5659782A
Authority
JP
Japan
Prior art keywords
compound
formula
production
cephalosporin derivative
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP13489279A
Other languages
Japanese (ja)
Inventor
Nobuhiro Oi
Bunya Aoki
Teizo Shinozaki
Kanji Moro
Isao Matsunaga
Takao Nofuji
Toshiyuki Nehashi
Yusuke Harada
Hisao Endo
Takao Kimura
Hiroshi Okazaki
Haruki Ogawa
Minoru Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP13489279A priority Critical patent/JPS5659782A/en
Publication of JPS5659782A publication Critical patent/JPS5659782A/en
Pending legal-status Critical Current

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Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of formula I (R1 is H, lower alkyl; R2 is 2 or 3 hydroxyl at least two of which are adjacent and in 2W6 positions, when R1 is H, in 3W5 positions, when R1 is lower alkyl; R3 is H, hydroxyl; R4 is H, lower alkoxy; R5 is H, acetoxy) or their salts.
EXAMPLE: 7-{ D( - )-α-[ 3-( 3,4-Dhydroxybenzoyl )-3-methyl-1-ureido ]-α-phenylacetamide}-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid.
USE: Antibacterial effective on gram-positive and -negative bacteria.
PREPARATION: A compound of formula II or its reactive derivative is made to react with a compound of X-(CO)m-Y (X is halogen; Y is halogen) and a compound of formula III or its reactive derivative to give the compound of formula I or its salt.
COPYRIGHT: (C)1981,JPO&Japio
JP13489279A 1979-10-19 1979-10-19 Production of novel cephalosporin derivative Pending JPS5659782A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13489279A JPS5659782A (en) 1979-10-19 1979-10-19 Production of novel cephalosporin derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13489279A JPS5659782A (en) 1979-10-19 1979-10-19 Production of novel cephalosporin derivative

Publications (1)

Publication Number Publication Date
JPS5659782A true JPS5659782A (en) 1981-05-23

Family

ID=15138947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13489279A Pending JPS5659782A (en) 1979-10-19 1979-10-19 Production of novel cephalosporin derivative

Country Status (1)

Country Link
JP (1) JPS5659782A (en)

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