JPS5659782A - Production of novel cephalosporin derivative - Google Patents
Production of novel cephalosporin derivativeInfo
- Publication number
- JPS5659782A JPS5659782A JP13489279A JP13489279A JPS5659782A JP S5659782 A JPS5659782 A JP S5659782A JP 13489279 A JP13489279 A JP 13489279A JP 13489279 A JP13489279 A JP 13489279A JP S5659782 A JPS5659782 A JP S5659782A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- production
- cephalosporin derivative
- hydroxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I (R1 is H, lower alkyl; R2 is 2 or 3 hydroxyl at least two of which are adjacent and in 2W6 positions, when R1 is H, in 3W5 positions, when R1 is lower alkyl; R3 is H, hydroxyl; R4 is H, lower alkoxy; R5 is H, acetoxy) or their salts.
EXAMPLE: 7-{ D( - )-α-[ 3-( 3,4-Dhydroxybenzoyl )-3-methyl-1-ureido ]-α-phenylacetamide}-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid.
USE: Antibacterial effective on gram-positive and -negative bacteria.
PREPARATION: A compound of formula II or its reactive derivative is made to react with a compound of X-(CO)m-Y (X is halogen; Y is halogen) and a compound of formula III or its reactive derivative to give the compound of formula I or its salt.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13489279A JPS5659782A (en) | 1979-10-19 | 1979-10-19 | Production of novel cephalosporin derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13489279A JPS5659782A (en) | 1979-10-19 | 1979-10-19 | Production of novel cephalosporin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5659782A true JPS5659782A (en) | 1981-05-23 |
Family
ID=15138947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13489279A Pending JPS5659782A (en) | 1979-10-19 | 1979-10-19 | Production of novel cephalosporin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5659782A (en) |
-
1979
- 1979-10-19 JP JP13489279A patent/JPS5659782A/en active Pending
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