JPS55143995A - Cephalosporin derivative and its preparation - Google Patents
Cephalosporin derivative and its preparationInfo
- Publication number
- JPS55143995A JPS55143995A JP5084179A JP5084179A JPS55143995A JP S55143995 A JPS55143995 A JP S55143995A JP 5084179 A JP5084179 A JP 5084179A JP 5084179 A JP5084179 A JP 5084179A JP S55143995 A JPS55143995 A JP S55143995A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- gram
- preparation
- cephalosporin derivative
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A cephalosporin derivative of formula I [R1 is H, lower alkanoyl, aralkyl, etc.; R2 is H, lower alkoxy, halogen, etc.; R3 is H or lower alkyl; R4 is H or OH; R5 is H or lower alkoxy; R6 is H, acetoxy, etc.; n is 1W3; m is 1Wn; ρm is a number which designates the position of substitution groups, and is 2W6 when R1 is not H or R3 is H].
EXAMPLE: 7-[D(-)-α[3-(3, 4-Dihydroxybenzoyl)-3-methyl-1-ureido]-α-phenylacetamido]-3-acetoxymethyl-3-cephem-4-carboxylic acid.
USE: Antibacterial agent effective to Gram-positive and Gram-negative bacteria.
PROCESS: A 7-aminocephalosporin of formula II (Y is H or protecting group) or its reactive derivative is made to react with a substituted ureidophenylacetic acid of formula III or its reactive derivative.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (48)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5084179A JPS55143995A (en) | 1979-04-26 | 1979-04-26 | Cephalosporin derivative and its preparation |
DK225179A DK225179A (en) | 1978-06-22 | 1979-05-30 | PROCEDURE FOR PREPARING CEPHALOSPORINE DERIVATIVES |
AU47695/79A AU524816B2 (en) | 1978-06-22 | 1979-06-01 | Cephalosporin derivatives |
GB7919441A GB2025944B (en) | 1978-06-22 | 1979-06-04 | Cephalosporins |
IL57480A IL57480A (en) | 1978-06-22 | 1979-06-05 | Benzoylureido cephalosporin derivatives,their preparation and antibacterial preparations containing them |
US06/047,781 US4298605A (en) | 1978-06-22 | 1979-06-11 | Cephalosporin derivatives |
CA329,615A CA1131617A (en) | 1978-06-22 | 1979-06-12 | Cephalosporin derivatives |
IT68273/79A IT1192777B (en) | 1978-06-22 | 1979-06-14 | Cephalosporin derivatives |
NO792036A NO792036L (en) | 1978-06-22 | 1979-06-19 | PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS |
CS794208A CS212222B2 (en) | 1978-06-22 | 1979-06-19 | Method of preparation of the 7-(substituted benzoylureido)-phenyl acetamido derivatives of the cephalosporine |
PT69794A PT69794A (en) | 1978-06-22 | 1979-06-21 | Sephalosporin derivatives |
SE7905520A SE7905520L (en) | 1978-06-22 | 1979-06-21 | cephalosporin derivatives |
FI791991A FI791991A (en) | 1978-06-22 | 1979-06-21 | KEFALOSPORINDERIVAT |
NL7904846A NL7904846A (en) | 1978-06-22 | 1979-06-21 | CEPHALOSPORIN DERIVATIVE, ITS PREPARATION AND USE IN AN ANTIBACTERIAL PREPARATION. |
DD79213817A DD144412A5 (en) | 1978-06-22 | 1979-06-21 | PROCESS FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES |
HU79CU164A HU178461B (en) | 1978-06-22 | 1979-06-21 | Process for producing 7-square bracket-bracket-benzoyl-ureido-bracket closed-phenyl-acetamido-square bracket closed-3-methyl-3-c3pheme-4-carboxylic acids |
BE2/57893A BE877139A (en) | 1978-06-22 | 1979-06-21 | CEPHALOSPORIN DERIVATIVES |
CH588179A CH640859A5 (en) | 1978-06-22 | 1979-06-22 | CEPHALOSPORINE DERIVATIVES. |
DE2925302A DE2925302C2 (en) | 1978-06-22 | 1979-06-22 | Acylureidocephalosporin derivatives and their use |
YU01477/79A YU147779A (en) | 1978-06-22 | 1979-06-22 | Process for preparing new cephalosporin derivatives |
ES481837A ES481837A1 (en) | 1978-06-22 | 1979-06-22 | Cephalosporin derivatives |
FR7916089A FR2429220A1 (en) | 1978-06-22 | 1979-06-22 | CEPHALOSPORIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION |
AT0440879A AT365196B (en) | 1978-06-22 | 1979-06-22 | METHOD FOR PRODUCING NEW CEPHALOSPORINE COMPOUNDS |
AR277005A AR231449A1 (en) | 1978-06-22 | 1979-07-22 | PROCEDURE FOR THE PREPARATION OF A BENZOIL-UREIDO-ACETAMIDO-CEFEM-CARBOXILICO ACID DERIVATIVE |
IE1182/79A IE48581B1 (en) | 1978-06-22 | 1979-08-08 | Benzolylureido-phenyl acetamido cephalosporins |
ES489646A ES8104303A1 (en) | 1978-06-22 | 1980-03-17 | Cephalosporin derivatives |
ES489645A ES8103099A1 (en) | 1978-06-22 | 1980-03-17 | Cephalosporin derivatives |
ES489648A ES489648A0 (en) | 1978-06-22 | 1980-03-17 | A PROCEDURE FOR THE PREPARATION OF A CEFA-LOSPORINA DERIVATIVE |
ES489647A ES8104305A1 (en) | 1978-06-22 | 1980-03-17 | Cephalosporin derivatives |
US06/136,063 US4328224A (en) | 1978-06-22 | 1980-03-28 | Cephalosporin derivatives |
US06/136,062 US4301161A (en) | 1978-06-22 | 1980-03-28 | Cephalosporin derivatives |
US06/136,061 US4341776A (en) | 1978-06-22 | 1980-03-28 | Cephalosporin derivatives |
CS802741A CS212225B2 (en) | 1978-06-22 | 1980-04-18 | Method of preparation of the 7-(substituted benzoylureido)-phenyl-acetamido derivatives of the cephalosporine |
CS802739A CS212223B2 (en) | 1978-09-11 | 1980-04-18 | Method of preparation of 7-( substituted benzolureido) phenyl-acetamido derivatives of the cephalosporine |
CS802742A CS212226B2 (en) | 1978-09-11 | 1980-04-18 | Method of preparation of 7-(substituted benzoylureido)- phenyl-acetoamido derivatives of the cephalosporine |
CS802740A CS212224B2 (en) | 1978-09-11 | 1980-04-18 | Method of preparation of 7-(substituted benzoylureido) phenylacetamido derivatives of the cephalosporine |
SU803211175A SU980626A3 (en) | 1978-09-11 | 1980-12-04 | Process for producing derivatives of cephalosporin or their alkali salts |
AT19281A AT369007B (en) | 1978-09-11 | 1981-01-19 | METHOD FOR PRODUCING NEW CEPHALOSPORINE DERIVATIVES |
AT19181A AT369006B (en) | 1978-09-11 | 1981-01-19 | METHOD FOR PRODUCING NEW CEPHALOSPORINE DERIVATIVES |
AT115281A AT372685B (en) | 1978-09-11 | 1981-03-12 | METHOD FOR PRODUCING NEW CEPHALOSPORINE DERIVATIVES |
AT0115181A AT371821B (en) | 1978-06-22 | 1981-03-12 | METHOD FOR PRODUCING NEW CEPHALOSPORINE DERIVATIVES |
AR284639A AR231294A1 (en) | 1978-06-22 | 1981-03-17 | PROCEDURE FOR THE PREPARATION OF A BENZOIL-UREIDO-ACETAMIDO-CEFEM-CARBOXILICO ACID DERIVATIVE |
AR28464281A AR228592A1 (en) | 1978-09-11 | 1981-03-17 | PROCEDURE FOR THE PREPARATION OF A DERIVATIVE OF AN ACID-BENZOILUREIDO-ACETAMIDO-CEFEM-CARBOXILICO |
AR28464081A AR231295A1 (en) | 1978-09-11 | 1981-03-17 | PROCEDURE FOR THE PREPARATION OF A BENZOILUREIDO-ACETAMIDO-CEFEM-CARBOXILICO ACID DERIVATIVE |
YU00546/83A YU54683A (en) | 1978-06-22 | 1983-03-07 | Process for obtining new cephalosporin derivatives |
YU00543/83A YU54383A (en) | 1978-06-22 | 1983-03-07 | Process for obtaining new cephalosporin derivatives |
YU54483A YU54483A (en) | 1978-09-11 | 1983-03-07 | Process for obtaining new cephalosporin derivatives |
YU00545/83A YU54583A (en) | 1978-06-22 | 1983-03-07 | Process for obtaining new cephalosporin derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5084179A JPS55143995A (en) | 1979-04-26 | 1979-04-26 | Cephalosporin derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55143995A true JPS55143995A (en) | 1980-11-10 |
Family
ID=12869959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5084179A Pending JPS55143995A (en) | 1978-06-22 | 1979-04-26 | Cephalosporin derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55143995A (en) |
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1979
- 1979-04-26 JP JP5084179A patent/JPS55143995A/en active Pending
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