JPS57106682A - Novel penicillins and their preparation - Google Patents

Novel penicillins and their preparation

Info

Publication number
JPS57106682A
JPS57106682A JP18173280A JP18173280A JPS57106682A JP S57106682 A JPS57106682 A JP S57106682A JP 18173280 A JP18173280 A JP 18173280A JP 18173280 A JP18173280 A JP 18173280A JP S57106682 A JPS57106682 A JP S57106682A
Authority
JP
Japan
Prior art keywords
compound
gram
bacteria
formula iii
pathogenic bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18173280A
Other languages
Japanese (ja)
Other versions
JPS6045879B2 (en
Inventor
Shigeo Shimizu
Hiroyuki Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIHON IYAKUHIN KAIHATSU KENKYU
NIHON IYAKUHIN KAIHATSU KENKYUSHO KK
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Original Assignee
NIHON IYAKUHIN KAIHATSU KENKYU
NIHON IYAKUHIN KAIHATSU KENKYUSHO KK
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIHON IYAKUHIN KAIHATSU KENKYU, NIHON IYAKUHIN KAIHATSU KENKYUSHO KK, NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK, SANKEI YAKUHIN KK filed Critical NIHON IYAKUHIN KAIHATSU KENKYU
Priority to JP18173280A priority Critical patent/JPS6045879B2/en
Publication of JPS57106682A publication Critical patent/JPS57106682A/en
Publication of JPS6045879B2 publication Critical patent/JPS6045879B2/en
Expired legal-status Critical Current

Links

Abstract

NEW MATERIAL:A penicillin compound of formulaI[R is H or (acylated) OH; -COOR' is (esterified) carboxyl; R1 and R2 are H or lower alkyl].
EXAMPLE: 6-[D-(-)-α-{[2-Oxo-3-(1,3-dithiolane-2-imino)-imidazolidin-1-yl]-carboxamido}-α-phenylacetamido]-penicillanic acid.
USE: It has excellent antibacterial activity against a wide variety of pathogenic bacteria such as Gram-negative bacteria, Gram-positive bacteria, etc. including Pseudomonas aeruginosa, and is useful for the prevention and remedy of diseases caused by the pathogenic bacteria.
PROCESS: The compound of formulaIis prepared by reacting the compound of formula II with the compound of formula III or its reactive derivative in a solvent such as water, at a low temperature, i.e. -50W+30°C. The compound of formula III used as a raw material is novel compound.
COPYRIGHT: (C)1982,JPO&Japio
JP18173280A 1980-12-22 1980-12-22 New penicillins and their production methods Expired JPS6045879B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18173280A JPS6045879B2 (en) 1980-12-22 1980-12-22 New penicillins and their production methods

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18173280A JPS6045879B2 (en) 1980-12-22 1980-12-22 New penicillins and their production methods

Publications (2)

Publication Number Publication Date
JPS57106682A true JPS57106682A (en) 1982-07-02
JPS6045879B2 JPS6045879B2 (en) 1985-10-12

Family

ID=16105910

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18173280A Expired JPS6045879B2 (en) 1980-12-22 1980-12-22 New penicillins and their production methods

Country Status (1)

Country Link
JP (1) JPS6045879B2 (en)

Also Published As

Publication number Publication date
JPS6045879B2 (en) 1985-10-12

Similar Documents

Publication Publication Date Title
JPS565487A (en) Cephalosporin compound, its preparation, and antimicrobial comprising it
JPS5547688A (en) Novel cephem compound and its preparation
JPS5573686A (en) Novel penicillin
JPS5746988A (en) Novel penicillin derivative and its preparation
JPS5643288A (en) Cephalosporin derivative and its preparation
JPS57106682A (en) Novel penicillins and their preparation
JPS5799592A (en) Novel cephalosporins
JPS5732290A (en) Novel penicillin derivative and its preparation
JPS5524135A (en) Penicillin derivative and its preparation
JPS54135767A (en) Penicillanic acid derivative
JPS5732289A (en) Alpha-substituted ureidobenzylpenicillin
JPS57165390A (en) Novel penicillin and cephalosporin derivative
JPS5655388A (en) Benzo ij quinolidine-2-carboxylic acid derivative, and its preparation
JPS5531044A (en) Penicillanic acid derivative and its preparation
JPS5718687A (en) Penicillin derivative and its salt
JPS5673087A (en) Cephalosporin derivative, its preparation and antimicrobial agent consisting of the same
JPS5640687A (en) Preparation of penicillanic acid derivative or its salt
JPS5572196A (en) Penicillanic acid derivative
JPS5665893A (en) Novel penicillin, and antibiotic agent containing said compound as effective component
JPS5549384A (en) Novel antibacterial compound
JPS56115788A (en) Azetidinone derivative and its preparation
JPS55136292A (en) Cephalosporin derivative, its preparation, and antibacterial comprising it
JPS5764698A (en) Cephem derivative, its preparation, and antibacterial agent composed of said derivative
JPS57165389A (en) Novel penicillin and cephalosporin compound
JPS57109792A (en) Penicillin derivative and salt thereof