JPS57165390A - Novel penicillin and cephalosporin derivative - Google Patents
Novel penicillin and cephalosporin derivativeInfo
- Publication number
- JPS57165390A JPS57165390A JP4843881A JP4843881A JPS57165390A JP S57165390 A JPS57165390 A JP S57165390A JP 4843881 A JP4843881 A JP 4843881A JP 4843881 A JP4843881 A JP 4843881A JP S57165390 A JPS57165390 A JP S57165390A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- salt
- acyloxy
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formulaI[R1 is H or methoxy; R2 is H or OH; R3 and R4 are OH or acyloxy; Y is O, S or >N-R5 (R5 is H or lower alkyl); X is group of formula II or formula III (R6 is acyloxy or N-containing heterocyclic-thio which may have substituent group)], its non-toxic salt and its carboxylic acid ester.
EXAMPLE: 6β-[ D-2-( 6,7-Diacetoxy-2-oxo-2H-1-benzopyran-3-carboxamido )-2- phenylacetamido]-penicillanic acid.
USE: Antibacterial agent having extremely strong antibacterial activity especially against Pseudomonas aeruginosa and Klebsiella pneumoniae.
PROCESS: The compound of formulaIis prepared by reacting the compound of formula IV, its salt or its hydrate with the compound of formula V or its reactive derivative (e.g. acid halide, symmetric acid anhydride, etc.), and if necessary, converting the product to the salt or ester.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4843881A JPS57165390A (en) | 1981-04-02 | 1981-04-02 | Novel penicillin and cephalosporin derivative |
US06/363,778 US4468394A (en) | 1981-04-02 | 1982-03-31 | Cephalosporin compounds |
EP82102830A EP0062328A3 (en) | 1981-04-02 | 1982-04-02 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4843881A JPS57165390A (en) | 1981-04-02 | 1981-04-02 | Novel penicillin and cephalosporin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57165390A true JPS57165390A (en) | 1982-10-12 |
Family
ID=12803350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4843881A Pending JPS57165390A (en) | 1981-04-02 | 1981-04-02 | Novel penicillin and cephalosporin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57165390A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5244892A (en) * | 1990-10-16 | 1993-09-14 | Kyorin Pharmaceutical Co., Ltd. | Cephem compounds, and antibacterial agents |
-
1981
- 1981-04-02 JP JP4843881A patent/JPS57165390A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5244892A (en) * | 1990-10-16 | 1993-09-14 | Kyorin Pharmaceutical Co., Ltd. | Cephem compounds, and antibacterial agents |
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