JPS5511541A - Novel antibiotics and their preparation - Google Patents

Novel antibiotics and their preparation

Info

Publication number
JPS5511541A
JPS5511541A JP8453778A JP8453778A JPS5511541A JP S5511541 A JPS5511541 A JP S5511541A JP 8453778 A JP8453778 A JP 8453778A JP 8453778 A JP8453778 A JP 8453778A JP S5511541 A JPS5511541 A JP S5511541A
Authority
JP
Japan
Prior art keywords
formula
preparation
molecular weight
ion exchange
exchange resin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8453778A
Other languages
Japanese (ja)
Other versions
JPS6331476B2 (en
Inventor
Takeo Ideushi
Akio Iwasaki
Kazuhiro Kamiya
Toshimi Mizoguchi
Masato Nakayama
Hisakatsu Itou
Toshito Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to JP8453778A priority Critical patent/JPS5511541A/en
Priority to US06/056,313 priority patent/US4312858A/en
Priority to NL7905464A priority patent/NL7905464A/en
Priority to FR7918102A priority patent/FR2430951B1/en
Priority to ES482443A priority patent/ES482443A1/en
Priority to GB7924425A priority patent/GB2028806B/en
Priority to DE2928373A priority patent/DE2928373C2/en
Priority to IT24358/79A priority patent/IT1122181B/en
Priority to FR8000974A priority patent/FR2457893A1/en
Publication of JPS5511541A publication Critical patent/JPS5511541A/en
Priority to US06/162,613 priority patent/US4329426A/en
Publication of JPS6331476B2 publication Critical patent/JPS6331476B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:An antibiotic KA-7038 IV of formula I; it is a white powder, melts at 78W82°C, has specific rotatory power of [α]D25=+115° (C=0.1 H2O), formula of C14H30O5N4, a molecular weight of 334, and another antibiotic of formula II, KA-7038V, which is a white powder, has a specific rotatory power of [α]D25 =+98°C (C=0.5 H2O), formula of C14H30O4N4, and molecular weight of 318.
USE: Antibiotics, which are effective against both gram-positive and -negative bacteria.
PREPARATION: Streptomyces KC-7038 (FERM-4388) or its mutant is aerobically cultured at 20W35°C for 2W10 days. The filtrate of the culture mixture is treated with ion exchange resin and others to give KA-7038 substances containing five components from I to V. Then they are adsorbed on ion exchange resin and eluted with aqueous ammonia to separate into each ingredient, which is further purified respectively.
COPYRIGHT: (C)1980,JPO&Japio
JP8453778A 1978-07-13 1978-07-13 Novel antibiotics and their preparation Granted JPS5511541A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP8453778A JPS5511541A (en) 1978-07-13 1978-07-13 Novel antibiotics and their preparation
US06/056,313 US4312858A (en) 1978-07-13 1979-07-10 Antibiotic KA-7038 and compositions containing same
GB7924425A GB2028806B (en) 1978-07-13 1979-07-12 Streptomycin antibiotics
FR7918102A FR2430951B1 (en) 1978-07-13 1979-07-12 ANTIBIOTICS, THEIR PREPARATION AND PREPARATION CULTURE
ES482443A ES482443A1 (en) 1978-07-13 1979-07-12 Antibiotic KA-7038 and compositions containing same
NL7905464A NL7905464A (en) 1978-07-13 1979-07-12 ANTIBIOTICS, METHOD FOR THE PREPARATION THEREOF, AND A BIOLOGICALLY PURE CULTURE FOR USE IN THIS METHOD.
DE2928373A DE2928373C2 (en) 1978-07-13 1979-07-13 Antibiotics KA-7038I to KA-7038VII, their salts, processes for their preparation and antibiotic agents containing these compounds
IT24358/79A IT1122181B (en) 1978-07-13 1979-07-13 ANTIBIOTICS, PROCEDURE FOR THEIR PREPARATION, AND BIOLOGICALLY PURE CULTURE FOR USE IN SUCH PROCEDURE
FR8000974A FR2457893A1 (en) 1978-07-13 1980-01-17 CULTURE OF THE STREPTOMYCE GENUS, USABLE IN PARTICULAR FOR THE PREPARATION OF ANTIBIOTICS
US06/162,613 US4329426A (en) 1978-07-13 1980-06-24 Process for preparation of antibiotics and biologically pure culture for use therein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8453778A JPS5511541A (en) 1978-07-13 1978-07-13 Novel antibiotics and their preparation

Publications (2)

Publication Number Publication Date
JPS5511541A true JPS5511541A (en) 1980-01-26
JPS6331476B2 JPS6331476B2 (en) 1988-06-23

Family

ID=13833384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8453778A Granted JPS5511541A (en) 1978-07-13 1978-07-13 Novel antibiotics and their preparation

Country Status (1)

Country Link
JP (1) JPS5511541A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102175422B1 (en) * 2018-11-29 2020-11-06 주식회사 포스코 Filtering panel and solar cell module having thereof

Also Published As

Publication number Publication date
JPS6331476B2 (en) 1988-06-23

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