JPS56115795A - Noval antibiotic substance mucopeptin b, and its preparation - Google Patents

Noval antibiotic substance mucopeptin b, and its preparation

Info

Publication number
JPS56115795A
JPS56115795A JP1964780A JP1964780A JPS56115795A JP S56115795 A JPS56115795 A JP S56115795A JP 1964780 A JP1964780 A JP 1964780A JP 1964780 A JP1964780 A JP 1964780A JP S56115795 A JPS56115795 A JP S56115795A
Authority
JP
Japan
Prior art keywords
mucopeptin
methanol
antibiotic substance
reaction
bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1964780A
Other languages
Japanese (ja)
Other versions
JPS577160B2 (en
Inventor
Kiyoshi Isono
Taketo Nakamura
Hiroo Kusakabe
Tomonobu Kusano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP1964780A priority Critical patent/JPS56115795A/en
Publication of JPS56115795A publication Critical patent/JPS56115795A/en
Publication of JPS577160B2 publication Critical patent/JPS577160B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

NEW MATERIAL:Antibiotic substance mucopeptin B having the following characteristics. Elemental analysis, C 55.12%, H 6.24%, N 9.47%; S 2.74%; molecular weight, 1022; melting point, 196W200°C (decomposition); specific rotatory power, [α]D25=-3.7° (C=0.92,50% methanol); UV absorption spectrum, shown in Fig.1; solubility, soluble in methanol, hydrated methanol, etc., hardly soluble in acetone, ethyl acetate, etc.; color reaction, positive to ninhydrin reaction, etc., negative to iron chloride reaction, etc.
USE: Drug having inhibiting activity to Gram-negative bacteria and acid-fast bacteria.
PROCESS: The objective antibiotic substance, mucopeptin B, is prepared by culturing bacteria belonging to Streptomyces genus and capable of producing antibiotic substance mucopeptin B [e.g. Streptomyces sp. K-64 (FERM-P No.5387)] under aeration and agitation, treating the filtrate of the cultivation product with active charcoal or an ion exchange resin, eluting the absorbed effective component with hydrated methanol from the absorbent, and concentrating and purifying the eluted solution.
COPYRIGHT: (C)1981,JPO&Japio
JP1964780A 1980-02-19 1980-02-19 Noval antibiotic substance mucopeptin b, and its preparation Granted JPS56115795A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1964780A JPS56115795A (en) 1980-02-19 1980-02-19 Noval antibiotic substance mucopeptin b, and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1964780A JPS56115795A (en) 1980-02-19 1980-02-19 Noval antibiotic substance mucopeptin b, and its preparation

Publications (2)

Publication Number Publication Date
JPS56115795A true JPS56115795A (en) 1981-09-11
JPS577160B2 JPS577160B2 (en) 1982-02-09

Family

ID=12005023

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1964780A Granted JPS56115795A (en) 1980-02-19 1980-02-19 Noval antibiotic substance mucopeptin b, and its preparation

Country Status (1)

Country Link
JP (1) JPS56115795A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39483E1 (en) 1992-10-30 2007-02-06 Kabushiki Kaisha Kenwood Optical disc player having program title display

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39483E1 (en) 1992-10-30 2007-02-06 Kabushiki Kaisha Kenwood Optical disc player having program title display

Also Published As

Publication number Publication date
JPS577160B2 (en) 1982-02-09

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