JPS55114290A - Substance with antitumorigenic activity, its production and medical preparation - Google Patents

Substance with antitumorigenic activity, its production and medical preparation

Info

Publication number
JPS55114290A
JPS55114290A JP2144179A JP2144179A JPS55114290A JP S55114290 A JPS55114290 A JP S55114290A JP 2144179 A JP2144179 A JP 2144179A JP 2144179 A JP2144179 A JP 2144179A JP S55114290 A JPS55114290 A JP S55114290A
Authority
JP
Japan
Prior art keywords
substance
propionibacterium
antitumorigenic activity
production
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2144179A
Other languages
Japanese (ja)
Other versions
JPS6230198B2 (en
Inventor
Yoshio Furuya
Tadashi Sudo
Koichi Konda
Tamotsu Fukuda
Osamu Yano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP2144179A priority Critical patent/JPS55114290A/en
Publication of JPS55114290A publication Critical patent/JPS55114290A/en
Publication of JPS6230198B2 publication Critical patent/JPS6230198B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PURPOSE: Cells of a microorganism belonging to Propionibacterium are broken and the resulting cell extract is treated with a coagulant to collect a substance with high antitumorigenic activity and low toxicity.
CONSTITUTION: A microorganism belonging to Propionibacterium, e.g., Propionibacterium avidum ATCC25577, is cultured by a usual anaerobic method. The resulting cells of the bacterium are broken and filtered or centrifuged to give the cell-free extract. A coagulant, e.g., a polyvalent metal salt, water-soluble basic antibiotic substance or its salt, is added to the extract to collect the substance with antitumorigenic activity as a precipitate.
COPYRIGHT: (C)1980,JPO&Japio
JP2144179A 1979-02-27 1979-02-27 Substance with antitumorigenic activity, its production and medical preparation Granted JPS55114290A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2144179A JPS55114290A (en) 1979-02-27 1979-02-27 Substance with antitumorigenic activity, its production and medical preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2144179A JPS55114290A (en) 1979-02-27 1979-02-27 Substance with antitumorigenic activity, its production and medical preparation

Publications (2)

Publication Number Publication Date
JPS55114290A true JPS55114290A (en) 1980-09-03
JPS6230198B2 JPS6230198B2 (en) 1987-07-01

Family

ID=12055044

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2144179A Granted JPS55114290A (en) 1979-02-27 1979-02-27 Substance with antitumorigenic activity, its production and medical preparation

Country Status (1)

Country Link
JP (1) JPS55114290A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165319A (en) * 1980-03-25 1982-10-12 Madaus & Co Dr Manufacture of cell-wall or whole cell medicine in tumor radiative or chemical treatment
JPS57163835U (en) * 1981-04-07 1982-10-15

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165319A (en) * 1980-03-25 1982-10-12 Madaus & Co Dr Manufacture of cell-wall or whole cell medicine in tumor radiative or chemical treatment
JPH0355448B2 (en) * 1980-03-25 1991-08-23
JPS57163835U (en) * 1981-04-07 1982-10-15

Also Published As

Publication number Publication date
JPS6230198B2 (en) 1987-07-01

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