JPS55114290A - Substance with antitumorigenic activity, its production and medical preparation - Google Patents
Substance with antitumorigenic activity, its production and medical preparationInfo
- Publication number
- JPS55114290A JPS55114290A JP2144179A JP2144179A JPS55114290A JP S55114290 A JPS55114290 A JP S55114290A JP 2144179 A JP2144179 A JP 2144179A JP 2144179 A JP2144179 A JP 2144179A JP S55114290 A JPS55114290 A JP S55114290A
- Authority
- JP
- Japan
- Prior art keywords
- substance
- propionibacterium
- antitumorigenic activity
- production
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
PURPOSE: Cells of a microorganism belonging to Propionibacterium are broken and the resulting cell extract is treated with a coagulant to collect a substance with high antitumorigenic activity and low toxicity.
CONSTITUTION: A microorganism belonging to Propionibacterium, e.g., Propionibacterium avidum ATCC25577, is cultured by a usual anaerobic method. The resulting cells of the bacterium are broken and filtered or centrifuged to give the cell-free extract. A coagulant, e.g., a polyvalent metal salt, water-soluble basic antibiotic substance or its salt, is added to the extract to collect the substance with antitumorigenic activity as a precipitate.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2144179A JPS55114290A (en) | 1979-02-27 | 1979-02-27 | Substance with antitumorigenic activity, its production and medical preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2144179A JPS55114290A (en) | 1979-02-27 | 1979-02-27 | Substance with antitumorigenic activity, its production and medical preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55114290A true JPS55114290A (en) | 1980-09-03 |
JPS6230198B2 JPS6230198B2 (en) | 1987-07-01 |
Family
ID=12055044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2144179A Granted JPS55114290A (en) | 1979-02-27 | 1979-02-27 | Substance with antitumorigenic activity, its production and medical preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55114290A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57165319A (en) * | 1980-03-25 | 1982-10-12 | Madaus & Co Dr | Manufacture of cell-wall or whole cell medicine in tumor radiative or chemical treatment |
JPS57163835U (en) * | 1981-04-07 | 1982-10-15 |
-
1979
- 1979-02-27 JP JP2144179A patent/JPS55114290A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57165319A (en) * | 1980-03-25 | 1982-10-12 | Madaus & Co Dr | Manufacture of cell-wall or whole cell medicine in tumor radiative or chemical treatment |
JPH0355448B2 (en) * | 1980-03-25 | 1991-08-23 | ||
JPS57163835U (en) * | 1981-04-07 | 1982-10-15 |
Also Published As
Publication number | Publication date |
---|---|
JPS6230198B2 (en) | 1987-07-01 |
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