JPS5659777A - Novel antibiotic, xk-213 and its preparation - Google Patents

Novel antibiotic, xk-213 and its preparation

Info

Publication number
JPS5659777A
JPS5659777A JP13588479A JP13588479A JPS5659777A JP S5659777 A JPS5659777 A JP S5659777A JP 13588479 A JP13588479 A JP 13588479A JP 13588479 A JP13588479 A JP 13588479A JP S5659777 A JPS5659777 A JP S5659777A
Authority
JP
Japan
Prior art keywords
antibiotic
streptomyces
methanol
preparation
echinosporus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13588479A
Other languages
Japanese (ja)
Other versions
JPS6241516B2 (en
Inventor
Makoto Okaji
Isao Kawamoto
Tomoyasu Sato
Tetsuo Oka
Kimikatsu Shirahata
Takao Iida
Noriaki Hirayama
Makoto Morimoto
Ryoji Imai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP13588479A priority Critical patent/JPS5659777A/en
Publication of JPS5659777A publication Critical patent/JPS5659777A/en
Publication of JPS6241516B2 publication Critical patent/JPS6241516B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

NEW MATERIAL:An antibiotic, XK-213, of the formula; appearance: white powder or white crystals; melting point: about 260 deg.C (decomposition); elementary analysis: (found in %), C 53.8, H 4.0, N 6.3; molecular equation: C10H9NO5; specific rotatory power: [alpha]D<25>=-400 deg. (C=0.1 in methanol); solubility: soluble in water, methanol, DMHA, insoluble in ethyl acetate, ethyl ether, n-hexane; coloring reaction: false-positive to ninhydrin reaction USE:Antibacterial and antitumorigenic: it is also used as a raw material that is converted into a derivative with high activity. PREPARATION:A microorganism that belongs to Streptomyces and produces the antibiotic XK-213, e.g., Streptomyces echinosporus MK-213 mold. (FERM-5229), is aerobically cultured in a liquid medium and the objective substance is adsorbed on an activated carbon by passing the filtrate of the culture mixture and eluted with 80% aqueous acetone to collect the antibiotic, XK-213.
JP13588479A 1979-10-23 1979-10-23 Novel antibiotic, xk-213 and its preparation Granted JPS5659777A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13588479A JPS5659777A (en) 1979-10-23 1979-10-23 Novel antibiotic, xk-213 and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13588479A JPS5659777A (en) 1979-10-23 1979-10-23 Novel antibiotic, xk-213 and its preparation

Publications (2)

Publication Number Publication Date
JPS5659777A true JPS5659777A (en) 1981-05-23
JPS6241516B2 JPS6241516B2 (en) 1987-09-03

Family

ID=15162028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13588479A Granted JPS5659777A (en) 1979-10-23 1979-10-23 Novel antibiotic, xk-213 and its preparation

Country Status (1)

Country Link
JP (1) JPS5659777A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054250A1 (en) * 2003-12-01 2005-06-16 Ocean University Of China Tricyclacetalactonin, Preparation and Use there of

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054250A1 (en) * 2003-12-01 2005-06-16 Ocean University Of China Tricyclacetalactonin, Preparation and Use there of

Also Published As

Publication number Publication date
JPS6241516B2 (en) 1987-09-03

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