JPS568688A - Antitumor substance 1166a and its preparation - Google Patents

Antitumor substance 1166a and its preparation

Info

Publication number
JPS568688A
JPS568688A JP8440879A JP8440879A JPS568688A JP S568688 A JPS568688 A JP S568688A JP 8440879 A JP8440879 A JP 8440879A JP 8440879 A JP8440879 A JP 8440879A JP S568688 A JPS568688 A JP S568688A
Authority
JP
Japan
Prior art keywords
reaction
methanol
soluble
substance
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8440879A
Other languages
Japanese (ja)
Other versions
JPS6144472B2 (en
Inventor
Hiroshi Yonehara
Nozomi Otake
Kazukiyo Onodera
Tomoyoshi Segawa
Keien Kiyo
Masanori Sugita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHIYUUGOKU SHINYAKU KOGYO KOFU
CHUGOKU SHINYAKU KOGYO KOFUNYUUGENKOUSHI
TOUBISHI YAKUHIN KOGYO KK
Tobishi Pharmaceutical Co Ltd
Nisshin Seifun Group Inc
Original Assignee
CHIYUUGOKU SHINYAKU KOGYO KOFU
CHUGOKU SHINYAKU KOGYO KOFUNYUUGENKOUSHI
TOUBISHI YAKUHIN KOGYO KK
Tobishi Pharmaceutical Co Ltd
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHIYUUGOKU SHINYAKU KOGYO KOFU, CHUGOKU SHINYAKU KOGYO KOFUNYUUGENKOUSHI, TOUBISHI YAKUHIN KOGYO KK, Tobishi Pharmaceutical Co Ltd, Nisshin Seifun Group Inc filed Critical CHIYUUGOKU SHINYAKU KOGYO KOFU
Priority to JP8440879A priority Critical patent/JPS568688A/en
Publication of JPS568688A publication Critical patent/JPS568688A/en
Publication of JPS6144472B2 publication Critical patent/JPS6144472B2/ja
Granted legal-status Critical Current

Links

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  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

NEW MATERIAL:Antitumor substance 1166A having the following properties: crystallizable from methanol solution as colorless acicular crystals; molecular weight 1107; elemental analysis, C62.51%, H8.93%, O27.96%; melting point, 156W159°C; specific rotatory power, [α]D20=-33.4° (1% methanol); specific UV absorption peak (in methanol), 254nm; specific IR absorption peaks (KBr tablet), 3400, 2950, 1695 and 1640cm-1 as shown in the Figure A; nuclear magnetic resonance absorption spectra for 1H and 13C are shown in the Figures B and C, respectively; soluble in methanol, acetone, etc.; partly soluble in ethyl acetate and butanol; slightly soluble in water, ethyl ether, etc.; positive to Ehrlich's reaction, Dragendorff's reaction, and anisaldehyde reaction; negative to ninhydrin reaction, Emery-Engel reaction, and ferric chloride reaction.
USE: Antitumor agent and antimicrobial agent.
PROCESS: Bacteria belonging to Streptomyces genus and capable of producing 1166A substance are cultured in a medium containing water-soluble nutrients under aerobic conditions, and the objective 1166A substance is separated from the cultured products.
COPYRIGHT: (C)1981,JPO&Japio
JP8440879A 1979-07-05 1979-07-05 Antitumor substance 1166a and its preparation Granted JPS568688A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8440879A JPS568688A (en) 1979-07-05 1979-07-05 Antitumor substance 1166a and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8440879A JPS568688A (en) 1979-07-05 1979-07-05 Antitumor substance 1166a and its preparation

Publications (2)

Publication Number Publication Date
JPS568688A true JPS568688A (en) 1981-01-29
JPS6144472B2 JPS6144472B2 (en) 1986-10-02

Family

ID=13829757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8440879A Granted JPS568688A (en) 1979-07-05 1979-07-05 Antitumor substance 1166a and its preparation

Country Status (1)

Country Link
JP (1) JPS568688A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63230233A (en) * 1987-03-18 1988-09-26 Agency Of Ind Science & Technol Preparation of precision punching die
US10596604B2 (en) 2016-09-27 2020-03-24 Texas Instruments Incorporated Methods and apparatus using multistage ultrasonic lens cleaning for improved water removal
US10663418B2 (en) 2017-02-03 2020-05-26 Texas Instruments Incorporated Transducer temperature sensing
US10682675B2 (en) 2016-11-01 2020-06-16 Texas Instruments Incorporated Ultrasonic lens cleaning system with impedance monitoring to detect faults or degradation
US10695805B2 (en) 2017-02-03 2020-06-30 Texas Instruments Incorporated Control system for a sensor assembly
US10780467B2 (en) 2017-04-20 2020-09-22 Texas Instruments Incorporated Methods and apparatus for surface wetting control
US10908414B2 (en) 2017-05-10 2021-02-02 Texas Instruments Incorporated Lens cleaning via electrowetting
US11042026B2 (en) 2017-02-24 2021-06-22 Texas Instruments Incorporated Transducer-induced heating and cleaning
US11237387B2 (en) 2016-12-05 2022-02-01 Texas Instruments Incorporated Ultrasonic lens cleaning system with foreign material detection

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63230233A (en) * 1987-03-18 1988-09-26 Agency Of Ind Science & Technol Preparation of precision punching die
JPH0354017B2 (en) * 1987-03-18 1991-08-16
US10596604B2 (en) 2016-09-27 2020-03-24 Texas Instruments Incorporated Methods and apparatus using multistage ultrasonic lens cleaning for improved water removal
US10682675B2 (en) 2016-11-01 2020-06-16 Texas Instruments Incorporated Ultrasonic lens cleaning system with impedance monitoring to detect faults or degradation
US11237387B2 (en) 2016-12-05 2022-02-01 Texas Instruments Incorporated Ultrasonic lens cleaning system with foreign material detection
US10663418B2 (en) 2017-02-03 2020-05-26 Texas Instruments Incorporated Transducer temperature sensing
US10695805B2 (en) 2017-02-03 2020-06-30 Texas Instruments Incorporated Control system for a sensor assembly
US11042026B2 (en) 2017-02-24 2021-06-22 Texas Instruments Incorporated Transducer-induced heating and cleaning
US10780467B2 (en) 2017-04-20 2020-09-22 Texas Instruments Incorporated Methods and apparatus for surface wetting control
US10908414B2 (en) 2017-05-10 2021-02-02 Texas Instruments Incorporated Lens cleaning via electrowetting
US11693235B2 (en) 2017-05-10 2023-07-04 Texas Instruments Incorporated Lens cleaning via electrowetting

Also Published As

Publication number Publication date
JPS6144472B2 (en) 1986-10-02

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