JPS5665897A - Antibiotic substance am-6201 and its preparation - Google Patents

Antibiotic substance am-6201 and its preparation

Info

Publication number
JPS5665897A
JPS5665897A JP14119579A JP14119579A JPS5665897A JP S5665897 A JPS5665897 A JP S5665897A JP 14119579 A JP14119579 A JP 14119579A JP 14119579 A JP14119579 A JP 14119579A JP S5665897 A JPS5665897 A JP S5665897A
Authority
JP
Japan
Prior art keywords
antibiotic substance
ethyl acetate
streptomyces
cultured
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14119579A
Other languages
Japanese (ja)
Inventor
Satoshi Omura
Atsushi Hirano
Yuzuru Iwai
Seisen Cho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Priority to JP14119579A priority Critical patent/JPS5665897A/en
Publication of JPS5665897A publication Critical patent/JPS5665897A/en
Pending legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:The antibiotic substance AM-6201 having the following physical and chemical properties: (1) molecular formula, C14H15NO6; (2) melting point, 216W220°C; and (3) specific rotation, [α]D26=+290.4° (c=1, chloroform).
USE: Antineoplasmic agent.
PROCESS: For example, a bacterial strain belonging to Streptomyces genus, e.g. Streptomyces sp. AM6201 (FERM-P No.5217), is cultured in a nutrient medium under aeration and agitation, pref. at pH6W7 and 25W30°C for 40W80hr. The cultured product is extracted with ethyl acetate, etc., and concentrated under rduced pressure. The produced precipitate is centrifuged, washed successively with n- hexane and ethanol, and recrystallized with ethyl acetate to obtain the objective antibiotic substance AM-6201 as a pale yellow acicular crystal.
COPYRIGHT: (C)1981,JPO&Japio
JP14119579A 1979-11-02 1979-11-02 Antibiotic substance am-6201 and its preparation Pending JPS5665897A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14119579A JPS5665897A (en) 1979-11-02 1979-11-02 Antibiotic substance am-6201 and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14119579A JPS5665897A (en) 1979-11-02 1979-11-02 Antibiotic substance am-6201 and its preparation

Publications (1)

Publication Number Publication Date
JPS5665897A true JPS5665897A (en) 1981-06-03

Family

ID=15286360

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14119579A Pending JPS5665897A (en) 1979-11-02 1979-11-02 Antibiotic substance am-6201 and its preparation

Country Status (1)

Country Link
JP (1) JPS5665897A (en)

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