JPS5665897A - Antibiotic substance am-6201 and its preparation - Google Patents
Antibiotic substance am-6201 and its preparationInfo
- Publication number
- JPS5665897A JPS5665897A JP14119579A JP14119579A JPS5665897A JP S5665897 A JPS5665897 A JP S5665897A JP 14119579 A JP14119579 A JP 14119579A JP 14119579 A JP14119579 A JP 14119579A JP S5665897 A JPS5665897 A JP S5665897A
- Authority
- JP
- Japan
- Prior art keywords
- antibiotic substance
- ethyl acetate
- streptomyces
- cultured
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:The antibiotic substance AM-6201 having the following physical and chemical properties: (1) molecular formula, C14H15NO6; (2) melting point, 216W220°C; and (3) specific rotation, [α]D26=+290.4° (c=1, chloroform).
USE: Antineoplasmic agent.
PROCESS: For example, a bacterial strain belonging to Streptomyces genus, e.g. Streptomyces sp. AM6201 (FERM-P No.5217), is cultured in a nutrient medium under aeration and agitation, pref. at pH6W7 and 25W30°C for 40W80hr. The cultured product is extracted with ethyl acetate, etc., and concentrated under rduced pressure. The produced precipitate is centrifuged, washed successively with n- hexane and ethanol, and recrystallized with ethyl acetate to obtain the objective antibiotic substance AM-6201 as a pale yellow acicular crystal.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14119579A JPS5665897A (en) | 1979-11-02 | 1979-11-02 | Antibiotic substance am-6201 and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14119579A JPS5665897A (en) | 1979-11-02 | 1979-11-02 | Antibiotic substance am-6201 and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5665897A true JPS5665897A (en) | 1981-06-03 |
Family
ID=15286360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14119579A Pending JPS5665897A (en) | 1979-11-02 | 1979-11-02 | Antibiotic substance am-6201 and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5665897A (en) |
-
1979
- 1979-11-02 JP JP14119579A patent/JPS5665897A/en active Pending
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