JPS5753498A - Tetrocarcins and their preparation - Google Patents

Tetrocarcins and their preparation

Info

Publication number
JPS5753498A
JPS5753498A JP12860580A JP12860580A JPS5753498A JP S5753498 A JPS5753498 A JP S5753498A JP 12860580 A JP12860580 A JP 12860580A JP 12860580 A JP12860580 A JP 12860580A JP S5753498 A JPS5753498 A JP S5753498A
Authority
JP
Japan
Prior art keywords
acetone
micromonospora
tetrocarcins
preparation
tetrocarcin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12860580A
Other languages
Japanese (ja)
Other versions
JPS6324000B2 (en
Inventor
Fusao Tomita
Tatsuya Tamaoki
Kimikatsu Shirahata
Masaji Kasai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP12860580A priority Critical patent/JPS5753498A/en
Priority to US06/252,062 priority patent/US4346075A/en
Publication of JPS5753498A publication Critical patent/JPS5753498A/en
Publication of JPS6324000B2 publication Critical patent/JPS6324000B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

NEW MATERIAL:Tetrocarcin F, G, and H of formula I (when R1 is -CHO, R2 is H, and when R1 is -CH2OH or -COOH, R2 is disaccharide residue) and their salts. The compounds have the following physicochemical properties; melting point (°C), F 201W204, G 194W198, H 211W216; specific rotation, F [α]D27=-49.4° (C=0.61, acetone), G [α]D25=-68.7° (C=1.0, acetone), H [α]D25=-69.2° (C= 0.72, acetone), elemental analysis (%), F, C=61.5, H=7.4, N=2.6 (corresponding to C55H76N2O19), G, C=61.0, H=7.6, H=2.1 (corresponding to C67H98N2O24, H, C=60.2, H=7.4, N=2.1 (corresponding to C67H96N2O25).
USE: Antifungal agent and antitumor agent.
PROCESS: Bacterial strain belonging to Micromonospora genus, e.g. Micromonospora chalcea KY11091 (FERM-P No.4458) is cultured at 28W38°C and pH 6W8 pref. in an agitated deep-tank fermentor.
COPYRIGHT: (C)1982,JPO&Japio
JP12860580A 1980-06-14 1980-09-18 Tetrocarcins and their preparation Granted JPS5753498A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP12860580A JPS5753498A (en) 1980-09-18 1980-09-18 Tetrocarcins and their preparation
US06/252,062 US4346075A (en) 1980-06-14 1981-04-08 Antibiotic DC-11 and process for production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12860580A JPS5753498A (en) 1980-09-18 1980-09-18 Tetrocarcins and their preparation

Publications (2)

Publication Number Publication Date
JPS5753498A true JPS5753498A (en) 1982-03-30
JPS6324000B2 JPS6324000B2 (en) 1988-05-18

Family

ID=14988903

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12860580A Granted JPS5753498A (en) 1980-06-14 1980-09-18 Tetrocarcins and their preparation

Country Status (1)

Country Link
JP (1) JPS5753498A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60102445A (en) * 1983-11-08 1985-06-06 株式会社長谷工コーポレーション Src structure of building
JPS60102444A (en) * 1983-11-08 1985-06-06 株式会社長谷工コ−ポレ−ション Precast skeletal of building
WO2000012494A1 (en) * 1998-08-31 2000-03-09 Kyowa Hakko Kogyo Co., Ltd. Apoptosis inducing agents

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01146899U (en) * 1988-04-01 1989-10-11

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60102445A (en) * 1983-11-08 1985-06-06 株式会社長谷工コーポレーション Src structure of building
JPS60102444A (en) * 1983-11-08 1985-06-06 株式会社長谷工コ−ポレ−ション Precast skeletal of building
JPH0326258B2 (en) * 1983-11-08 1991-04-10 Hasegawa Komuten Kk
JPH0360984B2 (en) * 1983-11-08 1991-09-18 Hasegawa Komuten Kk
WO2000012494A1 (en) * 1998-08-31 2000-03-09 Kyowa Hakko Kogyo Co., Ltd. Apoptosis inducing agents
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

Also Published As

Publication number Publication date
JPS6324000B2 (en) 1988-05-18

Similar Documents

Publication Publication Date Title
JPS55162791A (en) Antibiotic c-15003pnd and its preparation
JPS5615299A (en) Rhodomycin group antibiotic and its preparation
JPS5753498A (en) Tetrocarcins and their preparation
JPS5661398A (en) Substance dc-45 and its preparation
ES8302733A1 (en) Novel anthracycline derivative, process for production thereof, and pharmaceutical composition comprising said compound.
JPS57165399A (en) Novel anthracycline antibiotic substance and its preparation
JPS56125397A (en) Oligosaccharide derivative, its preparation and preventing agent against decayed tooth containing the same as active constituent
JPS57102897A (en) Antibiotic am-5344-a2 and its preparation
JPS5629598A (en) Novel amino sugar antibiotic g-367-2 and its preparation
JPS57171997A (en) Tetrocarcin and its preparation
JPS57171959A (en) Polyprenylsulfone derivative and its preparation
JPS5643295A (en) Istamycin ao and/or istamycin bo, and their preparation
JPS57200380A (en) Novel enzyme inhibitor mg 299-a substance and/or mg 299-b substance and their preparations
JPS55149297A (en) Antibiotic herbicidin c, e, f, and g and its preparation
JPS57114547A (en) Anthracycline antibiotic substance and its preparation
JPS5754196A (en) New antibiotic substance 76-11 and its preparation
JPS5559200A (en) New antibiotic substance sf-1999 and its preparation
JPS5592396A (en) Fr-3086 substance and its preparation
JPS55160788A (en) Novel antibiotic substance af-8, and its preparation
JPS5639098A (en) Novel oligosaccharide and its preparation
JPS5782397A (en) Novel antibiotic 5057b substance and its preparation
JPS5462392A (en) Preparation of antibiotic substance, sisomicin
JPS5782376A (en) Novel antibiotic substance saphenamycin and its preparation
JPS55122795A (en) Novel antibiotic substance xk-211 and its preparation
JPS5665897A (en) Antibiotic substance am-6201 and its preparation