JPS5753498A - Tetrocarcins and their preparation - Google Patents
Tetrocarcins and their preparationInfo
- Publication number
- JPS5753498A JPS5753498A JP12860580A JP12860580A JPS5753498A JP S5753498 A JPS5753498 A JP S5753498A JP 12860580 A JP12860580 A JP 12860580A JP 12860580 A JP12860580 A JP 12860580A JP S5753498 A JPS5753498 A JP S5753498A
- Authority
- JP
- Japan
- Prior art keywords
- acetone
- micromonospora
- tetrocarcins
- preparation
- tetrocarcin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
NEW MATERIAL:Tetrocarcin F, G, and H of formula I (when R1 is -CHO, R2 is H, and when R1 is -CH2OH or -COOH, R2 is disaccharide residue) and their salts. The compounds have the following physicochemical properties; melting point (°C), F 201W204, G 194W198, H 211W216; specific rotation, F [α]D27=-49.4° (C=0.61, acetone), G [α]D25=-68.7° (C=1.0, acetone), H [α]D25=-69.2° (C= 0.72, acetone), elemental analysis (%), F, C=61.5, H=7.4, N=2.6 (corresponding to C55H76N2O19), G, C=61.0, H=7.6, H=2.1 (corresponding to C67H98N2O24, H, C=60.2, H=7.4, N=2.1 (corresponding to C67H96N2O25).
USE: Antifungal agent and antitumor agent.
PROCESS: Bacterial strain belonging to Micromonospora genus, e.g. Micromonospora chalcea KY11091 (FERM-P No.4458) is cultured at 28W38°C and pH 6W8 pref. in an agitated deep-tank fermentor.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12860580A JPS5753498A (en) | 1980-09-18 | 1980-09-18 | Tetrocarcins and their preparation |
US06/252,062 US4346075A (en) | 1980-06-14 | 1981-04-08 | Antibiotic DC-11 and process for production thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12860580A JPS5753498A (en) | 1980-09-18 | 1980-09-18 | Tetrocarcins and their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5753498A true JPS5753498A (en) | 1982-03-30 |
JPS6324000B2 JPS6324000B2 (en) | 1988-05-18 |
Family
ID=14988903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12860580A Granted JPS5753498A (en) | 1980-06-14 | 1980-09-18 | Tetrocarcins and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5753498A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60102445A (en) * | 1983-11-08 | 1985-06-06 | 株式会社長谷工コーポレーション | Src structure of building |
JPS60102444A (en) * | 1983-11-08 | 1985-06-06 | 株式会社長谷工コ−ポレ−ション | Precast skeletal of building |
WO2000012494A1 (en) * | 1998-08-31 | 2000-03-09 | Kyowa Hakko Kogyo Co., Ltd. | Apoptosis inducing agents |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01146899U (en) * | 1988-04-01 | 1989-10-11 |
-
1980
- 1980-09-18 JP JP12860580A patent/JPS5753498A/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60102445A (en) * | 1983-11-08 | 1985-06-06 | 株式会社長谷工コーポレーション | Src structure of building |
JPS60102444A (en) * | 1983-11-08 | 1985-06-06 | 株式会社長谷工コ−ポレ−ション | Precast skeletal of building |
JPH0326258B2 (en) * | 1983-11-08 | 1991-04-10 | Hasegawa Komuten Kk | |
JPH0360984B2 (en) * | 1983-11-08 | 1991-09-18 | Hasegawa Komuten Kk | |
WO2000012494A1 (en) * | 1998-08-31 | 2000-03-09 | Kyowa Hakko Kogyo Co., Ltd. | Apoptosis inducing agents |
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
Also Published As
Publication number | Publication date |
---|---|
JPS6324000B2 (en) | 1988-05-18 |
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