JPS5754196A - New antibiotic substance 76-11 and its preparation - Google Patents
New antibiotic substance 76-11 and its preparationInfo
- Publication number
- JPS5754196A JPS5754196A JP55130374A JP13037480A JPS5754196A JP S5754196 A JPS5754196 A JP S5754196A JP 55130374 A JP55130374 A JP 55130374A JP 13037480 A JP13037480 A JP 13037480A JP S5754196 A JPS5754196 A JP S5754196A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- germs
- soluble
- fast
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:An antibiotic substance 76-11 having the following physico- chemical and biological properties: Elementary analysis %: C, 62.61; H, 8.27; N, 0 as the free acid. C, 60.57; H, 8.04; N, 0 as the Na salt. Molecular weight: 843 by the titration method and 873 by the FD mass spectrum method. Melting point: 108W112°C as the free acid and 210W212°C (decomposition) as the N salt. [α]D25=+36.6° (C=0.382, CHCl3). Readily soluble in benzene, acetone, etc., soluble in methanol, DMF, etc. and slightly soluble in water and hexane. Capable of aecoloring KMnO4 solution, but negative to the periodic acid-benzidine reaction and exhibiting the growth inhibitory action against Gram-positive cocci, bacilli and acid-fast germs at a concentration of 0.4mg/ml.
USE: An antimicrobial agent against Gram-positive bacteria, acid-fast germs, etc. including germs resistant to multiple drugs.
PROCESS: A strain of the genus Nocardia, e.g. Nocardia sp. 76-11 (FERM-P No. 5678), is cultivated.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55130374A JPS5754196A (en) | 1980-09-19 | 1980-09-19 | New antibiotic substance 76-11 and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55130374A JPS5754196A (en) | 1980-09-19 | 1980-09-19 | New antibiotic substance 76-11 and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5754196A true JPS5754196A (en) | 1982-03-31 |
JPS5733948B2 JPS5733948B2 (en) | 1982-07-20 |
Family
ID=15032824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55130374A Granted JPS5754196A (en) | 1980-09-19 | 1980-09-19 | New antibiotic substance 76-11 and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5754196A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170306A (en) * | 1982-03-30 | 1983-10-06 | 三菱電機株式会社 | Enclosed switchboard device |
JPS60251994A (en) * | 1984-05-29 | 1985-12-12 | Fuji Electric Corp Res & Dev Ltd | Method for controlling concentration of dissolved oxygen |
-
1980
- 1980-09-19 JP JP55130374A patent/JPS5754196A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58170306A (en) * | 1982-03-30 | 1983-10-06 | 三菱電機株式会社 | Enclosed switchboard device |
JPS60251994A (en) * | 1984-05-29 | 1985-12-12 | Fuji Electric Corp Res & Dev Ltd | Method for controlling concentration of dissolved oxygen |
JPH035239B2 (en) * | 1984-05-29 | 1991-01-25 | Fuji Denki Sogo Kenkyusho Kk |
Also Published As
Publication number | Publication date |
---|---|
JPS5733948B2 (en) | 1982-07-20 |
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