JPS5754196A - New antibiotic substance 76-11 and its preparation - Google Patents

New antibiotic substance 76-11 and its preparation

Info

Publication number
JPS5754196A
JPS5754196A JP55130374A JP13037480A JPS5754196A JP S5754196 A JPS5754196 A JP S5754196A JP 55130374 A JP55130374 A JP 55130374A JP 13037480 A JP13037480 A JP 13037480A JP S5754196 A JPS5754196 A JP S5754196A
Authority
JP
Japan
Prior art keywords
acid
germs
soluble
fast
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55130374A
Other languages
Japanese (ja)
Other versions
JPS5733948B2 (en
Inventor
Kiyoshi Isono
Taketo Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP55130374A priority Critical patent/JPS5754196A/en
Publication of JPS5754196A publication Critical patent/JPS5754196A/en
Publication of JPS5733948B2 publication Critical patent/JPS5733948B2/ja
Granted legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:An antibiotic substance 76-11 having the following physico- chemical and biological properties: Elementary analysis %: C, 62.61; H, 8.27; N, 0 as the free acid. C, 60.57; H, 8.04; N, 0 as the Na salt. Molecular weight: 843 by the titration method and 873 by the FD mass spectrum method. Melting point: 108W112°C as the free acid and 210W212°C (decomposition) as the N salt. [α]D25=+36.6° (C=0.382, CHCl3). Readily soluble in benzene, acetone, etc., soluble in methanol, DMF, etc. and slightly soluble in water and hexane. Capable of aecoloring KMnO4 solution, but negative to the periodic acid-benzidine reaction and exhibiting the growth inhibitory action against Gram-positive cocci, bacilli and acid-fast germs at a concentration of 0.4mg/ml.
USE: An antimicrobial agent against Gram-positive bacteria, acid-fast germs, etc. including germs resistant to multiple drugs.
PROCESS: A strain of the genus Nocardia, e.g. Nocardia sp. 76-11 (FERM-P No. 5678), is cultivated.
COPYRIGHT: (C)1982,JPO&Japio
JP55130374A 1980-09-19 1980-09-19 New antibiotic substance 76-11 and its preparation Granted JPS5754196A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55130374A JPS5754196A (en) 1980-09-19 1980-09-19 New antibiotic substance 76-11 and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55130374A JPS5754196A (en) 1980-09-19 1980-09-19 New antibiotic substance 76-11 and its preparation

Publications (2)

Publication Number Publication Date
JPS5754196A true JPS5754196A (en) 1982-03-31
JPS5733948B2 JPS5733948B2 (en) 1982-07-20

Family

ID=15032824

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55130374A Granted JPS5754196A (en) 1980-09-19 1980-09-19 New antibiotic substance 76-11 and its preparation

Country Status (1)

Country Link
JP (1) JPS5754196A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58170306A (en) * 1982-03-30 1983-10-06 三菱電機株式会社 Enclosed switchboard device
JPS60251994A (en) * 1984-05-29 1985-12-12 Fuji Electric Corp Res & Dev Ltd Method for controlling concentration of dissolved oxygen

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58170306A (en) * 1982-03-30 1983-10-06 三菱電機株式会社 Enclosed switchboard device
JPS60251994A (en) * 1984-05-29 1985-12-12 Fuji Electric Corp Res & Dev Ltd Method for controlling concentration of dissolved oxygen
JPH035239B2 (en) * 1984-05-29 1991-01-25 Fuji Denki Sogo Kenkyusho Kk

Also Published As

Publication number Publication date
JPS5733948B2 (en) 1982-07-20

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