JPS56139499A - Novel antibiotic substance, mucopeptin a and c, and their preparation - Google Patents
Novel antibiotic substance, mucopeptin a and c, and their preparationInfo
- Publication number
- JPS56139499A JPS56139499A JP4258480A JP4258480A JPS56139499A JP S56139499 A JPS56139499 A JP S56139499A JP 4258480 A JP4258480 A JP 4258480A JP 4258480 A JP4258480 A JP 4258480A JP S56139499 A JPS56139499 A JP S56139499A
- Authority
- JP
- Japan
- Prior art keywords
- substances
- mucopeptin
- decomposition
- methanol
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:Antibiotic substances, mucopeptin A and C, having the following physico-chemical and biological properties: Elemental analysis, (A) C 51.97%, H 6.19%, N 10.04%, S 2.34%, (C) C 51.27%, H 5.88%, N 11.86%, S 3.37%; molecular weight (titration method), (A) 1,120, (C) 800; melting point (A) 172W 180°C (decomposition ), (C) 178W182°C (decomposition); specific rotation, (A) [α]D20=-25.4°, (C)[α]D20=-39.7° (C=1.00, 50% methanol in both cases); solubility, both substances are soluble in water, methanol, etc., and hardly soluble in acetone, benzene, etc.; antibacterial spectrum, both substances have growth inhibtion activity to Gram-negative bacteria and acid-fast bacteria.
USE: Antibacterial agent against Gram-negative bacteria and acid-fast bacteria.
PROCESS: Streptomyces sp. K-64 strain (FREM-P No.5387) is cultured at 25W 35°C pref. under nearly neutral conditions, and the produced micopeptin A, C complex is separated into each constituent by chromatography, etc.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4258480A JPS56139499A (en) | 1980-04-01 | 1980-04-01 | Novel antibiotic substance, mucopeptin a and c, and their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4258480A JPS56139499A (en) | 1980-04-01 | 1980-04-01 | Novel antibiotic substance, mucopeptin a and c, and their preparation |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP57038893A Division JPS583676B2 (en) | 1982-03-12 | 1982-03-12 | Novel antibiotic mucopeptin C and its production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56139499A true JPS56139499A (en) | 1981-10-30 |
JPS5740160B2 JPS5740160B2 (en) | 1982-08-25 |
Family
ID=12640110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4258480A Granted JPS56139499A (en) | 1980-04-01 | 1980-04-01 | Novel antibiotic substance, mucopeptin a and c, and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56139499A (en) |
-
1980
- 1980-04-01 JP JP4258480A patent/JPS56139499A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5740160B2 (en) | 1982-08-25 |
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