JPS55102597A - Novel antibiotic substance, bactropone, and its preparation - Google Patents

Novel antibiotic substance, bactropone, and its preparation

Info

Publication number
JPS55102597A
JPS55102597A JP914279A JP914279A JPS55102597A JP S55102597 A JPS55102597 A JP S55102597A JP 914279 A JP914279 A JP 914279A JP 914279 A JP914279 A JP 914279A JP S55102597 A JPS55102597 A JP S55102597A
Authority
JP
Japan
Prior art keywords
antibiotic substance
soluble
bactropone
ethyl acetate
negative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP914279A
Other languages
Japanese (ja)
Other versions
JPS5832592B2 (en
Inventor
Hamao Umezawa
Tomio Takeuchi
Masa Hamada
Shinichi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP54009142A priority Critical patent/JPS5832592B2/en
Publication of JPS55102597A publication Critical patent/JPS55102597A/en
Publication of JPS5832592B2 publication Critical patent/JPS5832592B2/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:Antibiotic substance, bactropone. Appearance, colorless crystals (having no optical activity); decomposition point, 248W250°C; molecular formula, C7H5NO3; solubility, easily soluble in methanol, ethanol, acetone, dioxane, alkaline water, etc., soluble in ethyl acetate and butyl acetate, slightly soluble in water; color reactions, positive to Fast-blue-B, pentacyanoaquoferrate, ferric chloride reactions, etc., negative to ninhydrin reaction, Red.tetrazolium reaction, etc.
USE: A chemotherapeutic agent useful for the remedy of various infectious diseases. Low toxicity and high activity to inhibit the growth of various bacteria, esp. gram- negative bacteria.
PROCESS: The title antibiotic substance is prepared by (1) culturing chromobacterium BMF34-EG2 strain (FERM-P No.4769) aerobically in a liquid medium, and (2) extracting with a solvent such as ethyl acetate at ≤ph 5, or adsorbing with activated charcoal, or precipitating with a precipitant.
COPYRIGHT: (C)1980,JPO&Japio
JP54009142A 1979-01-31 1979-01-31 New antibiotic bactropon and its manufacturing method Expired JPS5832592B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP54009142A JPS5832592B2 (en) 1979-01-31 1979-01-31 New antibiotic bactropon and its manufacturing method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54009142A JPS5832592B2 (en) 1979-01-31 1979-01-31 New antibiotic bactropon and its manufacturing method

Publications (2)

Publication Number Publication Date
JPS55102597A true JPS55102597A (en) 1980-08-05
JPS5832592B2 JPS5832592B2 (en) 1983-07-14

Family

ID=11712370

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54009142A Expired JPS5832592B2 (en) 1979-01-31 1979-01-31 New antibiotic bactropon and its manufacturing method

Country Status (1)

Country Link
JP (1) JPS5832592B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096356A2 (en) * 1982-06-07 1983-12-21 Microbial Chemistry Research Foundation The novel microorganism strain Chromobacterium violaceum, pharmaceutically active compounds being produced by the strain, a process for preparing the compounds and the use of these compounds as medicaments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096356A2 (en) * 1982-06-07 1983-12-21 Microbial Chemistry Research Foundation The novel microorganism strain Chromobacterium violaceum, pharmaceutically active compounds being produced by the strain, a process for preparing the compounds and the use of these compounds as medicaments
EP0096356B1 (en) * 1982-06-07 1988-09-21 Microbial Chemistry Research Foundation The novel microorganism strain chromobacterium violaceum, pharmaceutically active compounds being produced by the strain, a process for preparing the compounds and the use of these compounds as medicaments

Also Published As

Publication number Publication date
JPS5832592B2 (en) 1983-07-14

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