FI81351C - Foerfarande foer framstaellning av farmakologiskt aktiva 2-pyridylsubstituerade 6,7-dihydro-3h,5h-pyrrolo/ 2,3-f/bentsimidazol-6-oner och -6-tioner. - Google Patents
Foerfarande foer framstaellning av farmakologiskt aktiva 2-pyridylsubstituerade 6,7-dihydro-3h,5h-pyrrolo/ 2,3-f/bentsimidazol-6-oner och -6-tioner. Download PDFInfo
- Publication number
- FI81351C FI81351C FI851869A FI851869A FI81351C FI 81351 C FI81351 C FI 81351C FI 851869 A FI851869 A FI 851869A FI 851869 A FI851869 A FI 851869A FI 81351 C FI81351 C FI 81351C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- compound
- pyridyl
- group
- carboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI883391A FI883391A (fi) | 1984-05-12 | 1988-07-15 | Saosom mellanprodukter anvaendbara indolinderivat. |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843417643 DE3417643A1 (de) | 1984-05-12 | 1984-05-12 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
DE3417643 | 1984-05-12 | ||
DE19843446417 DE3446417A1 (de) | 1984-12-20 | 1984-12-20 | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
DE3446417 | 1984-12-20 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI851869A0 FI851869A0 (fi) | 1985-05-10 |
FI851869L FI851869L (fi) | 1985-11-13 |
FI81351B FI81351B (fi) | 1990-06-29 |
FI81351C true FI81351C (fi) | 1990-10-10 |
Family
ID=25821132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI851869A FI81351C (fi) | 1984-05-12 | 1985-05-10 | Foerfarande foer framstaellning av farmakologiskt aktiva 2-pyridylsubstituerade 6,7-dihydro-3h,5h-pyrrolo/ 2,3-f/bentsimidazol-6-oner och -6-tioner. |
Country Status (18)
Country | Link |
---|---|
US (2) | US4666923A (fr) |
EP (1) | EP0161632B1 (fr) |
JP (2) | JPH0647593B2 (fr) |
KR (1) | KR870001201B1 (fr) |
AU (1) | AU560349B2 (fr) |
DE (1) | DE3582447D1 (fr) |
DK (1) | DK209585A (fr) |
ES (1) | ES8603178A1 (fr) |
FI (1) | FI81351C (fr) |
GR (1) | GR851085B (fr) |
HU (1) | HU193754B (fr) |
IL (1) | IL75120A (fr) |
NO (1) | NO851862L (fr) |
NZ (1) | NZ212005A (fr) |
PH (1) | PH22863A (fr) |
PL (2) | PL144822B1 (fr) |
PT (1) | PT80425B (fr) |
SU (1) | SU1480770A3 (fr) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR851085B (fr) * | 1984-05-12 | 1985-11-25 | Boehringer Mannheim Gmbh | |
DE3445669A1 (de) * | 1984-12-14 | 1986-06-19 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3501497A1 (de) * | 1985-01-18 | 1986-07-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
DE3524067A1 (de) * | 1985-07-05 | 1987-01-08 | Boehringer Mannheim Gmbh | Neue benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
DE3530825A1 (de) * | 1985-08-29 | 1987-03-05 | Boehringer Mannheim Gmbh | Neue benzodipyrrole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3531678A1 (de) * | 1985-09-05 | 1987-03-12 | Boehringer Mannheim Gmbh | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3626664A1 (de) * | 1986-08-07 | 1988-02-11 | Boehringer Mannheim Gmbh | Tricyclische benzotriazole, verfahren zu ihrer herstellung sowie arzneimittel |
DE3639466A1 (de) * | 1986-11-18 | 1988-05-19 | Thomae Gmbh Dr K | Neue pyrrolo-benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE3642315A1 (de) * | 1986-12-11 | 1988-06-23 | Boehringer Mannheim Gmbh | Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel |
DE3740985A1 (de) * | 1987-12-03 | 1989-06-15 | Boehringer Mannheim Gmbh | Verwendung linear anellierter tricyclen als hemmer der erythrozytenaggregation |
US4963677A (en) * | 1987-12-30 | 1990-10-16 | Orion Corporation Ltd. | Heterocyclic lactam compounds |
EP0322746B1 (fr) * | 1987-12-30 | 1996-05-29 | Orion Corporation Limited | Composés hétérocycliques |
DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
US5324911A (en) * | 1990-01-08 | 1994-06-28 | Schroer Manufacturing Company | Heated animal surgery table |
DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US20060142247A1 (en) * | 2004-12-17 | 2006-06-29 | Guy Georges | Tricyclic heterocycles |
AU2006233537A1 (en) * | 2005-04-14 | 2006-10-19 | F. Hoffmann-La Roche Ag | Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents |
WO2006108488A1 (fr) * | 2005-04-14 | 2006-10-19 | F. Hoffmann-La Roche Ag | Derives d'azole tricycliques, leur fabrication et leur utilisation en tant que principes pharmaceutiques |
EP1966213A1 (fr) * | 2005-12-15 | 2008-09-10 | F.Hoffmann-La Roche Ag | Dérivés tricycliques de lactame, leur fabrication et leur emploi en tant qu'agents pharmaceutiques |
JP2009530337A (ja) * | 2006-03-23 | 2009-08-27 | エフ.ホフマン−ラ ロシュ アーゲー | 置換インダゾール誘導体、その製造方法、及びその薬剤としての利用法 |
US8063225B2 (en) | 2006-08-14 | 2011-11-22 | Chembridge Corporation | Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
RU2443704C1 (ru) * | 2010-10-29 | 2012-02-27 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" | СУЛЬФАТЫ 2-АРИЛ-4-ДИАЛКИЛАМИНОЭТИЛ-3-ФЕНИЛПИРРОЛО[1,2-a]-БЕНЗИМИДАЗОЛОВ, ОБЛАДАЮЩИЕ АНТИОКСИДАНТНЫМИ И АНТИРАДИКАЛЬНЫМИ СВОЙСТВАМИ |
ES2664873T3 (es) | 2011-03-01 | 2018-04-23 | Synergy Pharmaceuticals Inc. | Proceso de preparación de agonistas de guanilato ciclasa C |
MX2015003330A (es) | 2012-09-13 | 2015-06-05 | Hoffmann La Roche | 2-oxo-2,3-dihidro-indoles para el tratamiento de trastornos del sistema nervioso central (cns). |
EP2958577A2 (fr) | 2013-02-25 | 2015-12-30 | Synergy Pharmaceuticals Inc. | Agonistes du recepteur de la guanylate cyclase pour l'utilisation dans l'irrigation du colon |
US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
KR20220147691A (ko) | 2013-08-09 | 2022-11-03 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
GB201709456D0 (en) * | 2017-06-14 | 2017-07-26 | Ucb Biopharma Sprl | Therapeutic agents |
JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス, インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
JP6854953B1 (ja) | 2020-06-16 | 2021-04-07 | 株式会社ソディック | ワイヤ放電加工装置 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1158532A (en) * | 1967-01-05 | 1969-07-16 | Centre Nat Rech Scient | 2-Oxoindoline-3-Carboxylic Acids and Esters thereof |
BE714717A (fr) * | 1967-05-12 | 1968-09-30 | ||
FR1529901A (fr) * | 1967-05-12 | 1968-06-21 | Centre Nat Rech Scient | Procédé de préparation de lactames se rattachant à l'indolinone et à l'oxo quinoléine |
US4322533A (en) * | 1980-03-17 | 1982-03-30 | Lesher George Y | 1H-Indole-2,3-dione derivatives |
CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
GR851085B (fr) * | 1984-05-12 | 1985-11-25 | Boehringer Mannheim Gmbh |
-
1985
- 1985-05-06 GR GR851085A patent/GR851085B/el unknown
- 1985-05-06 PL PL1985253246A patent/PL144822B1/pl unknown
- 1985-05-06 PL PL1985259261A patent/PL147842B1/pl unknown
- 1985-05-07 IL IL75120A patent/IL75120A/xx unknown
- 1985-05-07 US US06/731,500 patent/US4666923A/en not_active Expired - Lifetime
- 1985-05-07 NZ NZ212005A patent/NZ212005A/xx unknown
- 1985-05-08 PH PH32240A patent/PH22863A/en unknown
- 1985-05-09 EP EP85105675A patent/EP0161632B1/fr not_active Expired - Lifetime
- 1985-05-09 PT PT80425A patent/PT80425B/pt not_active IP Right Cessation
- 1985-05-09 ES ES542976A patent/ES8603178A1/es not_active Expired
- 1985-05-09 DE DE8585105675T patent/DE3582447D1/de not_active Expired - Lifetime
- 1985-05-09 AU AU42222/85A patent/AU560349B2/en not_active Ceased
- 1985-05-09 KR KR1019850003144A patent/KR870001201B1/ko not_active IP Right Cessation
- 1985-05-10 SU SU853894709A patent/SU1480770A3/ru active
- 1985-05-10 DK DK209585A patent/DK209585A/da not_active Application Discontinuation
- 1985-05-10 HU HU851775A patent/HU193754B/hu not_active IP Right Cessation
- 1985-05-10 NO NO851862A patent/NO851862L/no unknown
- 1985-05-10 FI FI851869A patent/FI81351C/fi not_active Application Discontinuation
- 1985-05-13 JP JP60099742A patent/JPH0647593B2/ja not_active Expired - Lifetime
-
1988
- 1988-07-05 US US07/217,143 patent/US4963686A/en not_active Expired - Fee Related
-
1993
- 1993-12-10 JP JP5310823A patent/JPH0772185B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU4222285A (en) | 1985-11-14 |
DE3582447D1 (de) | 1991-05-16 |
PL253246A1 (en) | 1986-08-26 |
EP0161632B1 (fr) | 1991-04-10 |
DK209585A (da) | 1985-11-13 |
JPH0772185B2 (ja) | 1995-08-02 |
KR850008170A (ko) | 1985-12-13 |
FI851869L (fi) | 1985-11-13 |
NO851862L (no) | 1985-11-13 |
AU560349B2 (en) | 1987-04-02 |
FI81351B (fi) | 1990-06-29 |
US4666923A (en) | 1987-05-19 |
PT80425B (de) | 1987-04-16 |
EP0161632A2 (fr) | 1985-11-21 |
GR851085B (fr) | 1985-11-25 |
KR870001201B1 (ko) | 1987-06-20 |
ES542976A0 (es) | 1986-01-01 |
PL147842B1 (en) | 1989-08-31 |
SU1480770A3 (ru) | 1989-05-15 |
ES8603178A1 (es) | 1986-01-01 |
PL144822B1 (en) | 1988-07-30 |
JPH0741474A (ja) | 1995-02-10 |
NZ212005A (en) | 1989-07-27 |
EP0161632A3 (en) | 1986-06-11 |
US4963686A (en) | 1990-10-16 |
JPH0647593B2 (ja) | 1994-06-22 |
JPS60246386A (ja) | 1985-12-06 |
PT80425A (de) | 1985-06-01 |
DK209585D0 (da) | 1985-05-10 |
HUT37938A (en) | 1986-03-28 |
PH22863A (en) | 1989-01-19 |
IL75120A0 (en) | 1985-09-29 |
IL75120A (en) | 1989-02-28 |
HU193754B (en) | 1987-11-30 |
FI851869A0 (fi) | 1985-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI81351C (fi) | Foerfarande foer framstaellning av farmakologiskt aktiva 2-pyridylsubstituerade 6,7-dihydro-3h,5h-pyrrolo/ 2,3-f/bentsimidazol-6-oner och -6-tioner. | |
AU746586B2 (en) | Quinazolinone inhibitors of cGMP phosphodiesterase | |
FI66604B (fi) | Foerfarande foer framstaellning av nya 5h-2,3-bensodiazepinderivat med inverkan pao det centrala nervsystemet | |
EP1910379B1 (fr) | Promédicaments d'inhibiteurs de la caspase | |
CA1216291A (fr) | Composes d'imidazoquinoxaline | |
IE901258L (en) | Pyrimidine derivatives | |
AU2018274378B2 (en) | Compound used as autophagy regulator, and preparation method therefor and uses thereof | |
JPH0784470B2 (ja) | 活性化合物、その製法及びそれを含む医薬組成物 | |
US4695567A (en) | Pyrrolobenzimidazoles, pharmaceutical compositions containing them and method of using them to treat certain heart and circulatory diseases | |
AU744540B2 (en) | 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives, addition salts thereof, and processes for the preparation of both | |
US4863945A (en) | Pyrrolobenzimidazoles and pharmaceutical compositions containing them | |
JPS63192773A (ja) | 三環式ベンズイミダゾール、その製法および該化合物を含有する血流障害治療剤 | |
EP0263352A1 (fr) | Imidazo-benzoxazinones, leur préparation et médicaments contenant ces composés | |
FI93444C (fi) | Menetelmä terapeuttisesti aktiivisten dihydropyridiinijohdannaisten valmistamiseksi | |
US4874756A (en) | Benzodipyrroles, processes for the preparation thereof and pharmaceutical compositions containing them | |
JPH0471914B2 (fr) | ||
IE63043B1 (en) | Cyclic amides | |
NO873108L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive 1,4-benzodiazepiner. | |
US4539400A (en) | Pyridin-3-yl substituted ortho-fused pyrrole derivatives | |
US4831032A (en) | Cardiotonic benzimidazoles | |
PT86154B (pt) | Processo para a preparacao de novos pirrolobenzimidazoles e de composicoes farmaceuticas que os contem | |
US4372956A (en) | 5, 10-Dihydroimidazo[2,1-b]quinazolines and pharmaceutical compositions containing them | |
DD234867A5 (de) | Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte | |
Kovač et al. | New synthesis of 11‐acyl‐5, 11‐dihydro‐6H‐pyrido [2, 3‐b][1, 4]‐benzodiazepin‐6‐ones and related studies | |
WO2000050420A1 (fr) | Derives d'acide 7-heteroquinoxaline carboxilique 6-substitue et leurs sels d'addition, procedes de preparation de ces derives et de leurs sels d'addition |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: BOEHRINGER MANNHEIM GMBH |