FI70405C - Analogifoerfarande foer framstaellning av terapeutiskt verksamma substituerade 1,1-dimetyl-(2-oxifenyl)alkylamino-etanolfoereningar - Google Patents

Analogifoerfarande foer framstaellning av terapeutiskt verksamma substituerade 1,1-dimetyl-(2-oxifenyl)alkylamino-etanolfoereningar Download PDF

Info

Publication number
FI70405C
FI70405C FI791118A FI791118A FI70405C FI 70405 C FI70405 C FI 70405C FI 791118 A FI791118 A FI 791118A FI 791118 A FI791118 A FI 791118A FI 70405 C FI70405 C FI 70405C
Authority
FI
Finland
Prior art keywords
compound
dimethyl
formula
group
methoxyphenyl
Prior art date
Application number
FI791118A
Other languages
English (en)
Finnish (fi)
Other versions
FI70405B (fi
FI791118A (fi
Inventor
Otto Agne Torsten Olsson
Nils Henry Alfons Persson
Leif Aoke Svensson
Carl Bertil Waldeck
Kjell Ingvar Leopold Wetterlin
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of FI791118A publication Critical patent/FI791118A/fi
Application granted granted Critical
Publication of FI70405B publication Critical patent/FI70405B/fi
Publication of FI70405C publication Critical patent/FI70405C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI791118A 1978-04-10 1979-04-04 Analogifoerfarande foer framstaellning av terapeutiskt verksamma substituerade 1,1-dimetyl-(2-oxifenyl)alkylamino-etanolfoereningar FI70405C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1403378 1978-04-10
GB1403378 1978-04-10

Publications (3)

Publication Number Publication Date
FI791118A FI791118A (fi) 1979-10-11
FI70405B FI70405B (fi) 1986-03-27
FI70405C true FI70405C (fi) 1986-09-19

Family

ID=10033794

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791118A FI70405C (fi) 1978-04-10 1979-04-04 Analogifoerfarande foer framstaellning av terapeutiskt verksamma substituerade 1,1-dimetyl-(2-oxifenyl)alkylamino-etanolfoereningar

Country Status (25)

Country Link
EP (1) EP0004835B1 (el)
JP (1) JPS54145624A (el)
AT (1) AT367022B (el)
AU (1) AU520787B2 (el)
BR (1) BR7902193A (el)
CA (1) CA1150296A (el)
CS (1) CS228114B2 (el)
CY (1) CY1228A (el)
DD (1) DD142875A5 (el)
DE (1) DE2960968D1 (el)
DK (1) DK146779A (el)
ES (2) ES479440A1 (el)
FI (1) FI70405C (el)
GR (1) GR66484B (el)
HK (1) HK35184A (el)
HU (1) HU178207B (el)
IE (1) IE48569B1 (el)
MY (1) MY8500403A (el)
NO (1) NO147103C (el)
NZ (1) NZ190078A (el)
PH (1) PH17202A (el)
PT (1) PT69459A (el)
SG (1) SG6984G (el)
SU (2) SU961557A3 (el)
ZA (1) ZA791403B (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6010021B2 (ja) * 1979-01-31 1985-03-14 田辺製薬株式会社 新規ベンジルアルコ−ル誘導体及びその製法
JPS6241829Y2 (el) * 1980-03-28 1987-10-26
GB2096988B (en) * 1980-11-20 1984-08-01 Beecham Group Ltd Aromatic hydroxyamines
US4454337A (en) * 1981-06-29 1984-06-12 Smithkline Beckman Corporation Semicarbazide intermediates for preparing 4-substituted indoles
CH653322A5 (de) * 1982-12-01 1985-12-31 Siegfried Ag Verfahren zur herstellung von phenylethanolaminen.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6610530A (el) * 1966-07-27 1968-01-29
DE1768167A1 (de) * 1968-04-06 1971-08-05 Troponwerke Dinklage & Co 1-(3-Hydroxyphenyl)-2-[3-phenyl-2-methylpropyl-(2)-amino]-aethynol-(1)
DE2008654A1 (de) * 1970-02-25 1971-09-09 C H Boehnnger Sohn, 6507 Ingel heim Ammoathanoldenvate
JPS52113934A (en) * 1976-03-19 1977-09-24 Eisai Co Ltd Phenethylamine derivatives and bronchodilator containing the same

Also Published As

Publication number Publication date
JPS54145624A (en) 1979-11-14
AU4568879A (en) 1980-10-09
HK35184A (en) 1984-05-04
IE48569B1 (en) 1985-03-06
MY8500403A (en) 1985-12-31
ES479440A1 (es) 1980-06-16
JPS638936B2 (el) 1988-02-25
DE2960968D1 (en) 1981-12-24
AT367022B (de) 1982-05-25
BR7902193A (pt) 1979-12-04
NO147103C (no) 1983-02-02
NZ190078A (en) 1984-07-06
ZA791403B (en) 1980-05-28
FI70405B (fi) 1986-03-27
SU1011046A3 (ru) 1983-04-07
NO147103B (no) 1982-10-25
CY1228A (en) 1984-06-29
ATA265579A (de) 1981-10-15
DK146779A (da) 1979-10-11
ES486580A1 (es) 1980-10-01
FI791118A (fi) 1979-10-11
HU178207B (en) 1982-03-28
GR66484B (el) 1981-03-24
SG6984G (en) 1984-08-03
AU520787B2 (en) 1982-02-25
IE790754L (en) 1979-10-10
CS228114B2 (en) 1984-05-14
PT69459A (en) 1979-05-01
DD142875A5 (de) 1980-07-16
EP0004835B1 (en) 1981-10-14
NO791199L (no) 1979-10-11
EP0004835A1 (en) 1979-10-17
PH17202A (en) 1984-06-19
SU961557A3 (ru) 1982-09-23
CA1150296A (en) 1983-07-19

Similar Documents

Publication Publication Date Title
DK168761B1 (da) Phenylethere og farmaceutisk acceptable salte deraf, fremgangsmåder til fremstilling heraf samt far maceutiske midler indeholdelde disse
US4822818A (en) Bicycle compounds, their production and use
DK157678B (da) Analogifremgangsmaade til fremstilling af amider af hydroxyfenylalkylaminoaetanoler eller terapeutisk acceptable salte deraf samt acetofenonderivat til anvendelse som udgangsmateriale ved fremgangsmaaden
NO174044B (no) Analogifremgangsmaate for fremstilling av et terapeutisk aktivt amid-derivat
JPS5892611A (ja) 抗繊維素溶解活性化合物及び抗繊維素溶解剤並びに抗繊維素溶解活性化合物の製造方法
CN102307836B (zh) 用于治疗疼痛的化合物
AT394552B (de) Verfahren zur herstellung des neuen n-(2-(4-fluor-phenyl)-1-methyl)-aethyl-n-methyl- propinylamin und isomeren und salzen desselben
WO1996039133A1 (en) Novel n-substituted-2-amino-3',4'-methylene-dioxypropiophenones
FI70405C (fi) Analogifoerfarande foer framstaellning av terapeutiskt verksamma substituerade 1,1-dimetyl-(2-oxifenyl)alkylamino-etanolfoereningar
DE3010752A1 (de) Substituierte aethanolamine
US5411955A (en) Thiadiazinecarboxamide derivatives, processes for their preparation and pharmaceuticals
US4374149A (en) α-{[(Arylalkyl)amino]alkyl}-4-hydroxy-3-(lower-alkylsulfinyl)benzenemethanols
EP3829560A1 (en) Compounds for the treatment of neurological or mitochondrial diseases
WO1996016942A1 (fr) Derives de pyridine
DE69006071T2 (de) Bronchospasmolytische Verbindungen und Verfahren zu ihrer Herstellung.
US11591284B2 (en) Compounds for the treatment of neuromuscular disorders
JP2756740B2 (ja) ２−シクロヘキセノン化合物及び該化合物を有効成分とする脳機能改善薬
FI70705B (fi) Foerfarande foer framstaellning av nya farmakologiskt verkandedekahydrokinolinolderivat
KR840001050B1 (ko) 페닐알킬아민 유도체의 제조방법
US20190183812A1 (en) Compounds For The Treatment Of Neuromuscular Disorders
CA2230359A1 (en) Desbutylhalofantrine compositions and use
KR800000251B1 (ko) 3-아미노-2-하이드록시 프로판의 디치환 페놀 에텔 유도체의 제조방법
FR2482956A1 (fr) Cyclohexylalkylamines, leurs procedes de preparation et leur application en therapeutique
CN106905238A (zh) 绿卡色林衍生物、其制法及减肥用途
JPS60161980A (ja) １，３−ジチオ−ル−２−イリデン誘導体

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: AKTIEBOLAGET DRACO