FI64354C - Foerfarande foer framstaellning av 2-hydroximetyl-3-hydroxi-6-(1-hydroxi-2-tert -butylaminoetyl)pyridin och dess dihydroklorid och vid foerfarandet som mellanprodukt anvaendbart maleinsyrasalt av 2-fenyl-6-(1-hydroxi-2-tert -butylaminoetyl)-4h-pyrido-(3,2-d)-1,3-dioxin - Google Patents

Foerfarande foer framstaellning av 2-hydroximetyl-3-hydroxi-6-(1-hydroxi-2-tert -butylaminoetyl)pyridin och dess dihydroklorid och vid foerfarandet som mellanprodukt anvaendbart maleinsyrasalt av 2-fenyl-6-(1-hydroxi-2-tert -butylaminoetyl)-4h-pyrido-(3,2-d)-1,3-dioxin Download PDF

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Publication number
FI64354C
FI64354C FI762693A FI762693A FI64354C FI 64354 C FI64354 C FI 64354C FI 762693 A FI762693 A FI 762693A FI 762693 A FI762693 A FI 762693A FI 64354 C FI64354 C FI 64354C
Authority
FI
Finland
Prior art keywords
tert
butylaminoethyl
hydroxi
hydroxy
och
Prior art date
Application number
FI762693A
Other languages
English (en)
Finnish (fi)
Other versions
FI64354B (fi
FI762693A (pl
Inventor
Ronnie D Carroll
James Ray Tretter
Bernard Shields Moore
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI762693A publication Critical patent/FI762693A/fi
Publication of FI64354B publication Critical patent/FI64354B/fi
Application granted granted Critical
Publication of FI64354C publication Critical patent/FI64354C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI762693A 1975-10-03 1976-09-21 Foerfarande foer framstaellning av 2-hydroximetyl-3-hydroxi-6-(1-hydroxi-2-tert -butylaminoetyl)pyridin och dess dihydroklorid och vid foerfarandet som mellanprodukt anvaendbart maleinsyrasalt av 2-fenyl-6-(1-hydroxi-2-tert -butylaminoetyl)-4h-pyrido-(3,2-d)-1,3-dioxin FI64354C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/619,302 US4011231A (en) 1975-10-03 1975-10-03 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate
US61930275 1975-10-03

Publications (3)

Publication Number Publication Date
FI762693A FI762693A (pl) 1977-04-04
FI64354B FI64354B (fi) 1983-07-29
FI64354C true FI64354C (fi) 1983-11-10

Family

ID=24481329

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762693A FI64354C (fi) 1975-10-03 1976-09-21 Foerfarande foer framstaellning av 2-hydroximetyl-3-hydroxi-6-(1-hydroxi-2-tert -butylaminoetyl)pyridin och dess dihydroklorid och vid foerfarandet som mellanprodukt anvaendbart maleinsyrasalt av 2-fenyl-6-(1-hydroxi-2-tert -butylaminoetyl)-4h-pyrido-(3,2-d)-1,3-dioxin

Country Status (30)

Country Link
US (1) US4011231A (pl)
JP (1) JPS5246081A (pl)
AR (1) AR213180A1 (pl)
AT (1) AT353789B (pl)
BE (1) BE846471A (pl)
BG (1) BG27544A3 (pl)
CA (1) CA1059518A (pl)
CH (1) CH616424A5 (pl)
CS (2) CS205042B2 (pl)
DD (2) DD133672A5 (pl)
DE (1) DE2640123C3 (pl)
DK (1) DK147049C (pl)
ES (2) ES451746A1 (pl)
FI (1) FI64354C (pl)
FR (1) FR2326191A1 (pl)
GB (1) GB1510075A (pl)
GR (1) GR61628B (pl)
HU (2) HU177493B (pl)
IE (1) IE43503B1 (pl)
LU (1) LU75898A1 (pl)
NL (1) NL164274C (pl)
NO (1) NO147027C (pl)
PH (1) PH14511A (pl)
PL (1) PL106863B1 (pl)
PT (1) PT65619B (pl)
RO (1) RO69886A (pl)
SE (2) SE428127B (pl)
SU (2) SU673168A3 (pl)
YU (1) YU39545B (pl)
ZA (1) ZA765253B (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477671A (en) * 1981-02-09 1984-10-16 Pfizer Inc. 3-Acetoxy or benzyloxy-2-acetoxymethyl-6-[1-acetoxy-2-(N-tert-butylacetamido)ethyl]pyridine intermediates
US4632992A (en) * 1981-02-09 1986-12-30 Pfizer Inc. Intermediates for preparing pirbuterol and analogs
US5395939A (en) * 1993-11-30 1995-03-07 North Carolina State University Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3250778A (en) * 1962-11-29 1966-05-10 Hoffmann La Roche Intermediates for and synthesis of vitamin b and related compounds
US3700681A (en) * 1971-02-16 1972-10-24 Pfizer 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines

Also Published As

Publication number Publication date
FI64354B (fi) 1983-07-29
US4011231A (en) 1977-03-08
NL7610683A (nl) 1977-04-05
NL164274C (nl) 1980-12-15
CA1059518A (en) 1979-07-31
DK147049B (da) 1984-03-26
NO763307L (pl) 1977-04-05
AT353789B (de) 1979-12-10
DE2640123B2 (de) 1980-01-31
IE43503B1 (en) 1981-03-11
IE43503L (en) 1977-04-03
FR2326191B1 (pl) 1978-11-17
SE7609497L (sv) 1977-04-04
PH14511A (en) 1981-08-24
DD133672A5 (de) 1979-01-17
ZA765253B (en) 1977-08-31
RO69886A (ro) 1981-09-24
PT65619A (en) 1976-10-01
HU177493B (en) 1981-10-28
PL106863B1 (pl) 1980-01-31
SU673168A3 (ru) 1979-07-05
HU172998B (hu) 1979-01-28
AU1788376A (en) 1978-03-16
SE428127B (sv) 1983-06-06
YU39545B (en) 1984-12-31
FR2326191A1 (fr) 1977-04-29
NL164274B (nl) 1980-07-15
DD129325A5 (de) 1978-01-11
CH616424A5 (pl) 1980-03-31
CS205042B2 (en) 1981-04-30
DK434176A (da) 1977-04-04
ATA692376A (de) 1979-05-15
LU75898A1 (pl) 1977-05-11
DE2640123A1 (de) 1977-04-07
BE846471A (fr) 1977-03-23
SE8003311L (sv) 1980-04-30
GR61628B (en) 1978-12-04
NO147027C (no) 1983-01-19
YU216576A (en) 1982-06-30
DK147049C (da) 1984-10-01
NO147027B (no) 1982-10-11
CS205041B2 (en) 1981-04-30
ES457257A1 (es) 1978-02-01
SU725562A3 (ru) 1980-03-30
ES451746A1 (es) 1977-08-16
AR213180A1 (es) 1978-12-29
GB1510075A (en) 1978-05-10
FI762693A (pl) 1977-04-04
JPS5519210B2 (pl) 1980-05-24
SE437159B (sv) 1985-02-11
BG27544A3 (en) 1979-11-12
JPS5246081A (en) 1977-04-12
DE2640123C3 (de) 1980-09-25
PT65619B (en) 1978-04-05

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Owner name: PFIZER INC.