FR2326191A1 - Procede de preparation de 2-hydroxymethyl - 3 - hydroxy - 6-(1-hydroxy-2-t-butylaminoethyl)pyridine, et intermediaires appropries - Google Patents

Procede de preparation de 2-hydroxymethyl - 3 - hydroxy - 6-(1-hydroxy-2-t-butylaminoethyl)pyridine, et intermediaires appropries

Info

Publication number
FR2326191A1
FR2326191A1 FR7628850A FR7628850A FR2326191A1 FR 2326191 A1 FR2326191 A1 FR 2326191A1 FR 7628850 A FR7628850 A FR 7628850A FR 7628850 A FR7628850 A FR 7628850A FR 2326191 A1 FR2326191 A1 FR 2326191A1
Authority
FR
France
Prior art keywords
hydroxy
butylaminoethyl
hydroxymethyl
pyridine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7628850A
Other languages
English (en)
Other versions
FR2326191B1 (fr
Inventor
Ronnie D Carroll
James Ray Tretter
Bernard Shields Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2326191A1 publication Critical patent/FR2326191A1/fr
Application granted granted Critical
Publication of FR2326191B1 publication Critical patent/FR2326191B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7628850A 1975-10-03 1976-09-24 Procede de preparation de 2-hydroxymethyl - 3 - hydroxy - 6-(1-hydroxy-2-t-butylaminoethyl)pyridine, et intermediaires appropries Granted FR2326191A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/619,302 US4011231A (en) 1975-10-03 1975-10-03 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate

Publications (2)

Publication Number Publication Date
FR2326191A1 true FR2326191A1 (fr) 1977-04-29
FR2326191B1 FR2326191B1 (fr) 1978-11-17

Family

ID=24481329

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7628850A Granted FR2326191A1 (fr) 1975-10-03 1976-09-24 Procede de preparation de 2-hydroxymethyl - 3 - hydroxy - 6-(1-hydroxy-2-t-butylaminoethyl)pyridine, et intermediaires appropries

Country Status (30)

Country Link
US (1) US4011231A (fr)
JP (1) JPS5246081A (fr)
AR (1) AR213180A1 (fr)
AT (1) AT353789B (fr)
BE (1) BE846471A (fr)
BG (1) BG27544A3 (fr)
CA (1) CA1059518A (fr)
CH (1) CH616424A5 (fr)
CS (2) CS205042B2 (fr)
DD (2) DD129325A5 (fr)
DE (1) DE2640123C3 (fr)
DK (1) DK147049C (fr)
ES (2) ES451746A1 (fr)
FI (1) FI64354C (fr)
FR (1) FR2326191A1 (fr)
GB (1) GB1510075A (fr)
GR (1) GR61628B (fr)
HU (2) HU172998B (fr)
IE (1) IE43503B1 (fr)
LU (1) LU75898A1 (fr)
NL (1) NL164274C (fr)
NO (1) NO147027C (fr)
PH (1) PH14511A (fr)
PL (1) PL106863B1 (fr)
PT (1) PT65619B (fr)
RO (1) RO69886A (fr)
SE (2) SE428127B (fr)
SU (2) SU673168A3 (fr)
YU (1) YU39545B (fr)
ZA (1) ZA765253B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632992A (en) * 1981-02-09 1986-12-30 Pfizer Inc. Intermediates for preparing pirbuterol and analogs
US4477671A (en) * 1981-02-09 1984-10-16 Pfizer Inc. 3-Acetoxy or benzyloxy-2-acetoxymethyl-6-[1-acetoxy-2-(N-tert-butylacetamido)ethyl]pyridine intermediates
US5395939A (en) * 1993-11-30 1995-03-07 North Carolina State University Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3250778A (en) * 1962-11-29 1966-05-10 Hoffmann La Roche Intermediates for and synthesis of vitamin b and related compounds
US3700681A (en) * 1971-02-16 1972-10-24 Pfizer 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines

Also Published As

Publication number Publication date
DE2640123C3 (de) 1980-09-25
AT353789B (de) 1979-12-10
DE2640123A1 (de) 1977-04-07
CS205041B2 (en) 1981-04-30
PT65619A (en) 1976-10-01
PL106863B1 (pl) 1980-01-31
LU75898A1 (fr) 1977-05-11
DK147049C (da) 1984-10-01
RO69886A (fr) 1981-09-24
NL164274B (nl) 1980-07-15
FR2326191B1 (fr) 1978-11-17
FI64354C (fi) 1983-11-10
CH616424A5 (fr) 1980-03-31
ES451746A1 (es) 1977-08-16
HU172998B (hu) 1979-01-28
HU177493B (en) 1981-10-28
NO147027C (no) 1983-01-19
SE437159B (sv) 1985-02-11
IE43503L (en) 1977-04-03
SE8003311L (sv) 1980-04-30
GR61628B (en) 1978-12-04
DK147049B (da) 1984-03-26
DD129325A5 (de) 1978-01-11
JPS5519210B2 (fr) 1980-05-24
FI762693A (fr) 1977-04-04
AR213180A1 (es) 1978-12-29
ATA692376A (de) 1979-05-15
DE2640123B2 (de) 1980-01-31
SE428127B (sv) 1983-06-06
FI64354B (fi) 1983-07-29
YU216576A (en) 1982-06-30
SE7609497L (sv) 1977-04-04
GB1510075A (en) 1978-05-10
NO763307L (fr) 1977-04-05
BG27544A3 (en) 1979-11-12
ZA765253B (en) 1977-08-31
SU725562A3 (ru) 1980-03-30
JPS5246081A (en) 1977-04-12
PH14511A (en) 1981-08-24
NL164274C (nl) 1980-12-15
PT65619B (en) 1978-04-05
CS205042B2 (en) 1981-04-30
NO147027B (no) 1982-10-11
NL7610683A (nl) 1977-04-05
DK434176A (da) 1977-04-04
US4011231A (en) 1977-03-08
IE43503B1 (en) 1981-03-11
DD133672A5 (de) 1979-01-17
CA1059518A (fr) 1979-07-31
SU673168A3 (ru) 1979-07-05
YU39545B (en) 1984-12-31
ES457257A1 (es) 1978-02-01
BE846471A (fr) 1977-03-23
AU1788376A (en) 1978-03-16

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0337, 920527

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0337, 760924

CL Concession to grant licences