FI114476B - Yksiastiamenetelmä pergolidin valmistamiseksi - Google Patents

Yksiastiamenetelmä pergolidin valmistamiseksi Download PDF

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Publication number
FI114476B
FI114476B FI932281A FI932281A FI114476B FI 114476 B FI114476 B FI 114476B FI 932281 A FI932281 A FI 932281A FI 932281 A FI932281 A FI 932281A FI 114476 B FI114476 B FI 114476B
Authority
FI
Finland
Prior art keywords
pergolide
mixture
reaction
med
prepare
Prior art date
Application number
FI932281A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI932281A (fi
FI932281A0 (fi
Inventor
Jerry Wayne Misner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI932281A0 publication Critical patent/FI932281A0/fi
Publication of FI932281A publication Critical patent/FI932281A/fi
Application granted granted Critical
Publication of FI114476B publication Critical patent/FI114476B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI932281A 1992-05-21 1993-05-19 Yksiastiamenetelmä pergolidin valmistamiseksi FI114476B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/886,800 US5463060A (en) 1992-05-21 1992-05-21 One-pot process
US88680092 1992-05-21

Publications (3)

Publication Number Publication Date
FI932281A0 FI932281A0 (fi) 1993-05-19
FI932281A FI932281A (fi) 1993-11-22
FI114476B true FI114476B (fi) 2004-10-29

Family

ID=25389802

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932281A FI114476B (fi) 1992-05-21 1993-05-19 Yksiastiamenetelmä pergolidin valmistamiseksi

Country Status (28)

Country Link
US (1) US5463060A (no)
EP (1) EP0571202B1 (no)
JP (1) JP3580565B2 (no)
KR (1) KR100285971B1 (no)
CN (1) CN1040438C (no)
AR (1) AR248023A1 (no)
AT (1) ATE203750T1 (no)
AU (1) AU656075B2 (no)
BR (1) BR9302016A (no)
CA (1) CA2095593C (no)
CZ (1) CZ283997B6 (no)
DE (1) DE69330506T2 (no)
DK (1) DK0571202T3 (no)
ES (1) ES2160587T3 (no)
FI (1) FI114476B (no)
GR (1) GR3037000T3 (no)
HU (1) HU210324B (no)
IL (1) IL105695A (no)
MX (1) MX9302883A (no)
MY (1) MY108884A (no)
NO (1) NO302416B1 (no)
NZ (1) NZ247545A (no)
PH (1) PH30663A (no)
PL (1) PL173522B1 (no)
PT (1) PT571202E (no)
RU (1) RU2108333C1 (no)
TW (1) TW215438B (no)
YU (1) YU49022B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1307934B1 (it) * 1999-01-27 2001-11-29 Poli Ind Chimica Spa Processo per la preparazione di derivati alchimercaptometilergolinici.
US6388079B1 (en) 2000-08-29 2002-05-14 Scinopharm Singapore Pte Ltd. Process for preparing pergolide
US20040242933A1 (en) * 2001-10-02 2004-12-02 Nobuo Matsui Process for preparation of ethene derivatives
US7019140B2 (en) * 2002-03-15 2006-03-28 Antibioticos S.P.A. Process for the synthesis of pergolide
CN110330495A (zh) * 2019-08-08 2019-10-15 重庆大学 一种合成麦角碱的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4782152A (en) * 1985-08-16 1988-11-01 Eli Lilly And Company Decyanation of pergolide intermediate

Also Published As

Publication number Publication date
HU210324B (en) 1995-03-28
HUT64539A (en) 1994-01-28
ES2160587T3 (es) 2001-11-16
DK0571202T3 (da) 2001-10-08
PH30663A (en) 1997-09-16
CA2095593C (en) 2003-09-30
MY108884A (en) 1996-11-30
DE69330506D1 (de) 2001-09-06
FI932281A (fi) 1993-11-22
US5463060A (en) 1995-10-31
NO931839L (no) 1993-11-22
CN1082544A (zh) 1994-02-23
CN1040438C (zh) 1998-10-28
FI932281A0 (fi) 1993-05-19
IL105695A (en) 1997-08-14
ATE203750T1 (de) 2001-08-15
JP3580565B2 (ja) 2004-10-27
AU3847693A (en) 1993-11-25
NZ247545A (en) 1995-03-28
RU2108333C1 (ru) 1998-04-10
YU34593A (sh) 1996-05-20
AU656075B2 (en) 1995-01-19
GR3037000T3 (en) 2002-01-31
AR248023A1 (es) 1995-05-31
HU9301460D0 (en) 1993-09-28
JPH069630A (ja) 1994-01-18
PT571202E (pt) 2001-11-30
EP0571202B1 (en) 2001-08-01
TW215438B (en) 1993-11-01
CZ283997B6 (cs) 1998-07-15
PL173522B1 (pl) 1998-03-31
CA2095593A1 (en) 1993-11-22
NO931839D0 (no) 1993-05-19
IL105695A0 (en) 1993-09-22
MX9302883A (es) 1993-11-01
DE69330506T2 (de) 2002-04-11
KR930023365A (ko) 1993-12-18
NO302416B1 (no) 1998-03-02
BR9302016A (pt) 1993-11-30
EP0571202A1 (en) 1993-11-24
CZ93793A3 (en) 1994-01-19
PL299010A1 (en) 1993-12-27
YU49022B (sh) 2003-07-07
KR100285971B1 (ko) 2001-05-02

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