ES2743050T5 - Composiciones y procedimientos para cuantificar una secuencia de ácido nucleico en una muestra - Google Patents
Composiciones y procedimientos para cuantificar una secuencia de ácido nucleico en una muestra Download PDFInfo
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- ES2743050T5 ES2743050T5 ES13775206T ES13775206T ES2743050T5 ES 2743050 T5 ES2743050 T5 ES 2743050T5 ES 13775206 T ES13775206 T ES 13775206T ES 13775206 T ES13775206 T ES 13775206T ES 2743050 T5 ES2743050 T5 ES 2743050T5
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261621975P | 2012-04-09 | 2012-04-09 | |
PCT/US2013/035750 WO2013155056A1 (en) | 2012-04-09 | 2013-04-09 | Compositions and methods for quantifying a nucleic acid sequence in a sample |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2743050T3 ES2743050T3 (es) | 2020-02-18 |
ES2743050T5 true ES2743050T5 (es) | 2022-10-20 |
Family
ID=49328090
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES19175608T Active ES3011408T3 (en) | 2012-04-09 | 2013-04-09 | Compositions and methods for quantifying a nucleic acid sequence in a sample |
ES13775206T Active ES2743050T5 (es) | 2012-04-09 | 2013-04-09 | Composiciones y procedimientos para cuantificar una secuencia de ácido nucleico en una muestra |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES19175608T Active ES3011408T3 (en) | 2012-04-09 | 2013-04-09 | Compositions and methods for quantifying a nucleic acid sequence in a sample |
Country Status (18)
Country | Link |
---|---|
US (8) | US9096897B2 (enEXAMPLES) |
EP (3) | EP4524265A3 (enEXAMPLES) |
JP (4) | JP5801513B2 (enEXAMPLES) |
KR (4) | KR101570951B1 (enEXAMPLES) |
CN (2) | CN114134207A (enEXAMPLES) |
AU (3) | AU2013246080C1 (enEXAMPLES) |
BR (1) | BR112014025262A8 (enEXAMPLES) |
CA (1) | CA2869971C (enEXAMPLES) |
DK (2) | DK2836609T4 (enEXAMPLES) |
ES (2) | ES3011408T3 (enEXAMPLES) |
FI (1) | FI3587587T3 (enEXAMPLES) |
IN (1) | IN2014DN08831A (enEXAMPLES) |
MX (2) | MX338296B (enEXAMPLES) |
NZ (2) | NZ723570A (enEXAMPLES) |
RU (2) | RU2601129C2 (enEXAMPLES) |
UA (2) | UA116205C2 (enEXAMPLES) |
WO (1) | WO2013155056A1 (enEXAMPLES) |
ZA (3) | ZA201408116B (enEXAMPLES) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012021493A2 (en) | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
EP4524265A3 (en) | 2012-04-09 | 2025-06-25 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
MX386087B (es) | 2014-04-22 | 2025-03-18 | Envirologix Inc | Composiciones y metodos para mejorar y/o predecir la amplificacion de adn. |
BR112016025349A2 (pt) * | 2014-04-30 | 2017-12-12 | Envirologix Inc | composições e métodos para a detecção de huanglongbing |
EP3207159B1 (en) * | 2014-10-14 | 2019-11-20 | Abbott Laboratories | Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same |
CN107208137A (zh) * | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
CA2975236A1 (en) * | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
CN107532206B (zh) * | 2015-01-30 | 2022-08-05 | 一龙公司 | 底物分子 |
CA3021580A1 (en) * | 2015-06-25 | 2016-12-29 | Barry L. Merriman | Biomolecular sensors and methods |
WO2017014963A1 (en) * | 2015-07-20 | 2017-01-26 | Envirologix Inc. | Compositions and methods for rapid detection of salmonella serovar d1 |
EP3368654A4 (en) * | 2015-10-30 | 2019-06-05 | Alere Inc. | DETERMINATION OF POLYMORPHISMS BY ISOTHERMIC NUCLEIC ACID AMPLIFICATION |
US10329601B2 (en) | 2015-12-28 | 2019-06-25 | Ionian Technologies, Inc. | Nicking and extension amplification reaction (NEAR) of Streptococcus species |
KR20250022239A (ko) | 2016-01-28 | 2025-02-14 | 로스웰 엠이 아이엔씨. | 대량 병렬 dna 시퀀싱 장치 |
US11624725B2 (en) | 2016-01-28 | 2023-04-11 | Roswell Blotechnologies, Inc. | Methods and apparatus for measuring analytes using polymerase in large scale molecular electronics sensor arrays |
CA3053103A1 (en) | 2016-02-09 | 2017-08-17 | Roswell Biotechnologies, Inc. | Electronic label-free dna and genome sequencing |
US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
GB201611469D0 (en) * | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
CN110431148A (zh) | 2017-01-10 | 2019-11-08 | 罗斯威尔生命技术公司 | 用于dna数据存储的方法和系统 |
KR102601324B1 (ko) | 2017-01-19 | 2023-11-10 | 로스웰 바이오테크놀로지스 인코포레이티드 | 2차원 레이어 재료를 포함하는 솔리드 스테이트 시퀀싱 디바이스들 |
CN110546276A (zh) | 2017-04-25 | 2019-12-06 | 罗斯威尔生命技术公司 | 用于分子传感器的酶电路 |
US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
KR102606670B1 (ko) | 2017-05-09 | 2023-11-24 | 로스웰 바이오테크놀로지스 인코포레이티드 | 분자 센서들을 위한 결합 프로브 회로들 |
US10538808B2 (en) | 2017-05-26 | 2020-01-21 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
TWI754652B (zh) * | 2017-07-10 | 2022-02-11 | 英商盧米瑞德克斯英國有限公司 | 核酸擴增方法中或相關之改良 |
EP3676389A4 (en) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | PROCESSIVE ENZYMATIC MOLECULAR ELECTRONIC SENSORS FOR STORING DNA DATA |
WO2019046610A1 (en) | 2017-08-31 | 2019-03-07 | Ionian Technologies Inc. | REACTION OF SYNCHRONIZATION AMPLIFICATION AND (NEAR) EXTENSION OF SYNCYTIAL RESPIRATORY VIRUS SPECIES |
US11100404B2 (en) | 2017-10-10 | 2021-08-24 | Roswell Biotechnologies, Inc. | Methods, apparatus and systems for amplification-free DNA data storage |
GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
CN108588252A (zh) * | 2018-03-29 | 2018-09-28 | 杭州泰熙生物技术有限公司 | 一种寄生虫检测试剂盒及其检测方法 |
US12319712B2 (en) | 2018-05-09 | 2025-06-03 | Vibrant Holdings, Llc | Methods of synthesizing a polynucleotide array using photoactivated agents |
JP2021528091A (ja) * | 2018-06-26 | 2021-10-21 | ザ・ブロード・インスティテュート・インコーポレイテッド | Crisprダブルニッカーゼに基づく増幅の組成物、システム、及び方法 |
GB201812149D0 (en) | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
KR102154628B1 (ko) | 2019-01-03 | 2020-09-10 | 베트올 (주) | 반정량 수평류 면역진단 기술을 이용한 랄스토니아 솔라나세아룸과 푸사리움 옥시스포룸의 동시 진단 방법 |
KR102199394B1 (ko) * | 2019-07-01 | 2021-01-06 | 한국화학연구원 | 이중분자비콘과 산화그래핀을 포함하는 핵산 검출용 조성물 및 이를 이용한 핵산 검출의 비색신호 증폭 방법 |
KR102531590B1 (ko) * | 2019-07-16 | 2023-05-11 | 고려대학교 산학협력단 | 절단효소 인식부위의 미러링 결합에 의한 표적핵산의 검출 방법 및 핵산 검출용 조성물 |
CN110408678A (zh) * | 2019-07-26 | 2019-11-05 | 宁儿医院股份有限公司 | 单管型多重微生物检测体系及其即时检测方法 |
WO2021226205A1 (en) * | 2020-05-07 | 2021-11-11 | Bioskryb, Inc. | Detection of low abundance nucleic acids |
WO2022169846A1 (en) * | 2021-02-02 | 2022-08-11 | Rhodx, Inc. | Synthetic polynucleotides and methods for selectively amplifying alleles |
EP4444907A1 (en) * | 2021-12-08 | 2024-10-16 | Massachusetts Institute of Technology | Cold-temperature isothermal amplification of polynucleotides |
WO2023221939A1 (en) * | 2022-05-14 | 2023-11-23 | Jiangsu Code Biomedical Technology Co., Ltd. | Novel compositions and methods for cell-free dna detection |
EP4547865A1 (en) * | 2022-07-01 | 2025-05-07 | Sherlock Biosciences, Inc. | Ambient temperature nucleic acid amplification and detection |
EP4565720A1 (en) | 2022-08-04 | 2025-06-11 | Abbott Laboratories | Assays for detecting monkeypox virus |
WO2025049451A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting cytomegalovirus (cmv) or epstein-bar virus (ebv) |
WO2025049450A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting bk virus (bkv) |
Family Cites Families (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
US5629179A (en) | 1995-03-17 | 1997-05-13 | Novagen, Inc. | Method and kit for making CDNA library |
AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
CA2249717A1 (en) * | 1996-03-18 | 1997-09-25 | Richard K. Wilkosz | Target nucleic acid sequence amplification |
AU726821B2 (en) * | 1996-07-16 | 2000-11-23 | Gen-Probe Incorporated | Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific Tm |
GB9716231D0 (en) | 1997-07-31 | 1997-10-08 | Amersham Int Ltd | Base analogues |
US6355421B1 (en) | 1997-10-27 | 2002-03-12 | Boston Probes, Inc. | Methods, kits and compositions pertaining to PNA molecular beacons |
US5952202A (en) | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
WO2000028084A1 (en) | 1998-11-06 | 2000-05-18 | Molecular Biology Resources, Inc. | Isothermal nucleic acid amplification methods |
US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
WO2001090415A2 (en) * | 2000-05-20 | 2001-11-29 | The Regents Of The University Of Michigan | Method of producing a dna library using positional amplification |
US6191267B1 (en) | 2000-06-02 | 2001-02-20 | New England Biolabs, Inc. | Cloning and producing the N.BstNBI nicking endonuclease |
ES2254306T3 (es) * | 2000-10-25 | 2006-06-16 | F. Hoffmann-La Roche Ag | Amplificacion usando cebadores modificados. |
CA2433330A1 (en) | 2000-12-27 | 2002-07-25 | Invitrogen Corporation | Primers and methods for the detection and discrimination of nucleic acids |
WO2003008622A2 (en) * | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Exponential nucleic acid amplification using nicking endonucleases |
CA2492220C (en) | 2001-07-15 | 2014-03-18 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
JPWO2003016569A1 (ja) * | 2001-08-20 | 2004-12-02 | タカラバイオ株式会社 | 核酸の増幅方法 |
US6617137B2 (en) | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
US6977148B2 (en) | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
US20030211483A1 (en) | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
US7662594B2 (en) | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
DE60324810D1 (de) | 2002-09-20 | 2009-01-02 | New England Biolabs Inc | HELICASE-ABHuNGIGE AMPLIFIKATION VON NUKLEINSUREN |
WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
JP4380305B2 (ja) | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
US20090017452A1 (en) | 2004-03-05 | 2009-01-15 | University Of Chicago | Methods and compositions relating to the pharmacogenetics of different gene variants |
US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
JP5068175B2 (ja) * | 2005-01-04 | 2012-11-07 | 日立化成工業株式会社 | プライマー生成ローリングサークル型増幅 |
JP4555136B2 (ja) * | 2005-03-31 | 2010-09-29 | 本田技研工業株式会社 | 燃料電池の電気システム、燃料電池車両及び電力供給方法 |
EP1929049B1 (en) | 2005-07-25 | 2013-04-10 | Alere San Diego, Inc. | Methods for multiplexing recombinase polymerase amplification |
DK1924704T3 (da) | 2005-08-02 | 2011-09-05 | Rubicon Genomics Inc | Sammensætninger og fremgangsmåder til bearbejdning og mangfoldiggørelse af DNA, herunder ved anvendelse af flere enzymer i en enkelt reaktion |
EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
US7947286B2 (en) | 2005-10-07 | 2011-05-24 | Panthera Biopharma Llc | Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain |
US20090092967A1 (en) * | 2006-06-26 | 2009-04-09 | Epoch Biosciences, Inc. | Method for generating target nucleic acid sequences |
US20080096257A1 (en) | 2006-08-15 | 2008-04-24 | Zuxu Yao | Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids |
DE102006039396A1 (de) | 2006-08-22 | 2008-03-13 | Robert Bosch Gmbh | Laserlichtquelle |
EP2071927A2 (en) | 2006-09-28 | 2009-06-24 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
JP2010505396A (ja) | 2006-10-06 | 2010-02-25 | ディーエヌエー ジェノテック インク | リボ核酸を抽出するための安定化組成物および方法 |
JP2008136451A (ja) | 2006-12-05 | 2008-06-19 | Hitachi Ltd | 核酸増幅法 |
US8202972B2 (en) | 2007-01-10 | 2012-06-19 | General Electric Company | Isothermal DNA amplification |
US20090081760A1 (en) † | 2007-01-12 | 2009-03-26 | Monsanto Technology Llc | Dmo methods and compositions |
US20080254458A1 (en) | 2007-04-10 | 2008-10-16 | Asiagen Corporation | Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis |
US20080274458A1 (en) | 2007-05-01 | 2008-11-06 | Latham Gary J | Nucleic acid quantitation methods |
US9689031B2 (en) * | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
WO2009020609A2 (en) | 2007-08-06 | 2009-02-12 | Nanogen, Inc. | Isolation of nucleic acids molecules using modified solid supports |
US20090197254A1 (en) | 2007-12-14 | 2009-08-06 | Ming-Chou Lee | Variant scorpion primers for nucleic acid amplification and detection |
US20090325169A1 (en) | 2008-04-30 | 2009-12-31 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
WO2010026933A1 (ja) | 2008-09-03 | 2010-03-11 | タカラバイオ株式会社 | Rna検出用組成物 |
AU2010206492B2 (en) | 2009-01-21 | 2012-07-12 | Human Genetic Signatures Pty Ltd | Improved isothermal strand displacement amplification |
WO2010107946A2 (en) | 2009-03-18 | 2010-09-23 | Sequenom, Inc. | Use of thermostable endonucleases for generating reporter molecules |
WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
WO2012021493A2 (en) * | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
EP2420579A1 (en) * | 2010-08-17 | 2012-02-22 | QIAGEN GmbH | Helicase dependent isothermal amplification using nicking enzymes |
ES2684525T3 (es) | 2011-09-15 | 2018-10-03 | David A. Shafer | Composiciones de sonda:antisonda para detección de ADN o ARN de alta especificidad |
US20130217071A1 (en) | 2011-12-30 | 2013-08-22 | Luz Montesclaros | Methods and compositions for performing nucleic acid amplification reactions |
EP4524265A3 (en) | 2012-04-09 | 2025-06-25 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
JP6382189B2 (ja) | 2012-06-29 | 2018-08-29 | ゼネラル・エレクトリック・カンパニイ | Rnaテンプレートから開始する等温dna増幅用のキット |
JP2014082936A (ja) | 2012-10-19 | 2014-05-12 | Kyoto Univ | 変異型逆転写酵素 |
MX386087B (es) | 2014-04-22 | 2025-03-18 | Envirologix Inc | Composiciones y metodos para mejorar y/o predecir la amplificacion de adn. |
BR112016025349A2 (pt) | 2014-04-30 | 2017-12-12 | Envirologix Inc | composições e métodos para a detecção de huanglongbing |
CN107208137A (zh) | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
CA2965657A1 (en) | 2014-10-28 | 2016-05-06 | Envirologix Inc. | Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis |
CA2975236A1 (en) | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
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