ES2735289T3 - Proteínas de unión a cdim y usos de las mismas - Google Patents
Proteínas de unión a cdim y usos de las mismas Download PDFInfo
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- ES2735289T3 ES2735289T3 ES13713588T ES13713588T ES2735289T3 ES 2735289 T3 ES2735289 T3 ES 2735289T3 ES 13713588 T ES13713588 T ES 13713588T ES 13713588 T ES13713588 T ES 13713588T ES 2735289 T3 ES2735289 T3 ES 2735289T3
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- cdim
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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| US201261633330P | 2012-02-08 | 2012-02-08 | |
| PCT/US2013/025430 WO2013120012A2 (en) | 2012-02-08 | 2013-02-08 | Cdim binding proteins and uses thereof |
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| ES2735289T3 true ES2735289T3 (es) | 2019-12-17 |
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| EP3560954B1 (en) | 2014-04-03 | 2021-08-04 | IGM Biosciences, Inc. | Modified j-chain |
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| US10570191B2 (en) | 2015-04-17 | 2020-02-25 | Igm Biosciences, Inc. | Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof |
| FI3355913T3 (fi) | 2015-09-30 | 2024-12-02 | Igm Biosciences Inc | Muokatun j-ketjun sisältäviä sitoutuvia molekyylejä |
| JP7058213B2 (ja) | 2015-09-30 | 2022-04-21 | アイジーエム バイオサイエンシズ インコーポレイテッド | 改変ｊ鎖を有する結合分子 |
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| BR112020015994A2 (pt) | 2018-02-08 | 2020-12-15 | Dragonfly Therapeutics, Inc. | Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer |
| FI3749346T3 (fi) | 2018-02-08 | 2024-09-04 | Dragonfly Therapeutics Inc | Nkg2d-reseptoriin kohdistuvat vasta-aineen vaihtelevan domeenin yhdistelmät |
| KR102832460B1 (ko) | 2018-02-20 | 2025-07-11 | 드래곤플라이 쎄라퓨틱스, 인크. | Cd33, nkg2d, 및 cd16에 결합하는 다중-특이적 결합 단백질, 및 이의 사용 방법 |
| BR112020017296A2 (pt) | 2018-03-01 | 2020-12-29 | Igm Biosciences, Inc. | Mutações de igm fc e de cadeia j que afetam a meia-vida sérica de igm |
| JP7482363B2 (ja) | 2018-08-08 | 2024-05-14 | ドラゴンフライ セラピューティクス， インコーポレイテッド | Ｎｋｇ２ｄ、ｃｄ１６及び腫瘍関連抗原に結合するタンパク質 |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| SG11202100883SA (en) | 2018-08-08 | 2021-02-25 | Dragonfly Therapeutics Inc | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| MX2021005751A (es) * | 2018-11-16 | 2021-10-01 | Memorial Sloan Kettering Cancer Center | Anticuerpos contra mucina 16 y métodos de uso de los mismos. |
| US20230203119A1 (en) | 2019-08-15 | 2023-06-29 | Igm Biosciences, Inc. | Immunostimulatory multimeric binding molecules |
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| CN117222663A (zh) | 2021-03-03 | 2023-12-12 | 蜻蜓疗法股份有限公司 | 使用结合nkg2d、cd16和肿瘤相关抗原的多特异性结合蛋白治疗癌症的方法 |
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| BRPI0517057A (pt) * | 2004-11-05 | 2008-09-30 | Palingen Inc | composição para induzir ferimento de membrana celular; composição para aumentar o ferimento da membrana celular em uma célula linfóide; composição para permeabilizar uma célula; composição para induzir ferimento da membrana celular em células b; composição para aumentar o ferimento da membrana celular induzido por um anticorpo de ferimento de membrana celular; método de tratamento de um mamìfero que sofre de uma condição distinta por uma hiperproliferação de células; método para matar uma célula cancerosa; método para induzir ferimento de membrana celular em uma célula linfóide em um paciente humano; método para induzir ferimento da membrana celular; método para permeabilizar uma célula; método de purgar a medula óssea de células b malignas de um paciente com esta necessidade; estojo para determinar o limite da dose para um agente polivalente que induz o ferimento da membrana celular em um mamìfero; estojo para determinar o limite da dose para um anticorpo de ferimento de membrana celular em um mamìfero; uso de um agente polivalente de ferimento de membrana celular; e uso de um anticorpo de ferimento de membrana celular |
| AU2005333155B2 (en) * | 2005-03-14 | 2011-11-17 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies against Hendra and Nipah viruses |
| WO2007035857A2 (en) * | 2005-09-19 | 2007-03-29 | Palingen, Inc. | Treatment of b cell diseases using anti-germline antibody binding agents |
| RU2009140313A (ru) * | 2007-04-02 | 2011-05-10 | Эмджен Фримонт Инк. (Us) | АНТИТЕЛА ПРОТИВ IgE |
-
2013
- 2013-02-08 EP EP13713588.5A patent/EP2812356B1/en active Active
- 2013-02-08 JP JP2014556751A patent/JP6335796B2/ja active Active
- 2013-02-08 AU AU2013200903A patent/AU2013200903B2/en active Active
- 2013-02-08 ES ES13713588T patent/ES2735289T3/es active Active
- 2013-02-08 BR BR112014019459-9A patent/BR112014019459B1/pt active IP Right Grant
- 2013-02-08 IN IN1781MUN2014 patent/IN2014MN01781A/en unknown
- 2013-02-08 CA CA2863714A patent/CA2863714C/en active Active
- 2013-02-08 CN CN201380008515.XA patent/CN104254544B/zh active Active
- 2013-02-08 TW TW102105337A patent/TWI606064B/zh active
- 2013-02-08 US US13/763,398 patent/US9409976B2/en active Active
- 2013-02-08 WO PCT/US2013/025430 patent/WO2013120012A2/en active Application Filing
- 2013-02-08 DK DK13713588.5T patent/DK2812356T3/da active
- 2013-02-08 KR KR1020147025110A patent/KR102102111B1/ko active Active
- 2013-02-08 MX MX2014009628A patent/MX363819B/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US9409976B2 (en) | 2016-08-09 |
| CA2863714C (en) | 2022-07-05 |
| DK2812356T3 (da) | 2019-07-08 |
| WO2013120012A2 (en) | 2013-08-15 |
| MX2014009628A (es) | 2015-03-19 |
| BR112014019459A8 (pt) | 2023-01-10 |
| CA2863714A1 (en) | 2013-08-15 |
| TW201345921A (zh) | 2013-11-16 |
| MX363819B (es) | 2019-04-03 |
| CN104254544B (zh) | 2017-04-26 |
| AU2013200903A1 (en) | 2013-08-22 |
| HK1205136A1 (en) | 2015-12-11 |
| IN2014MN01781A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-07-03 |
| KR20150001728A (ko) | 2015-01-06 |
| BR112014019459A2 (pt) | 2017-06-27 |
| AU2013200903B2 (en) | 2015-05-14 |
| JP6335796B2 (ja) | 2018-06-06 |
| EP2812356B1 (en) | 2019-03-27 |
| US20140044739A1 (en) | 2014-02-13 |
| TWI606064B (zh) | 2017-11-21 |
| KR102102111B1 (ko) | 2020-04-20 |
| WO2013120012A3 (en) | 2013-11-07 |
| BR112014019459B1 (pt) | 2023-04-18 |
| JP2015511817A (ja) | 2015-04-23 |
| EP2812356A2 (en) | 2014-12-17 |
| CN104254544A (zh) | 2014-12-31 |
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