AU2013200903B2 - CDIM binding proteins and uses thereof - Google Patents
CDIM binding proteins and uses thereof Download PDFInfo
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- AU2013200903B2 AU2013200903B2 AU2013200903A AU2013200903A AU2013200903B2 AU 2013200903 B2 AU2013200903 B2 AU 2013200903B2 AU 2013200903 A AU2013200903 A AU 2013200903A AU 2013200903 A AU2013200903 A AU 2013200903A AU 2013200903 B2 AU2013200903 B2 AU 2013200903B2
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- antigen binding
- binding protein
- cdim
- seq
- antibody
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| AU2015210362A AU2015210362A1 (en) | 2012-02-08 | 2015-08-05 | Cdim binding proteins and uses thereof |
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| PT3126383T (pt) | 2014-04-03 | 2019-03-22 | Igm Biosciences Inc | Cadeia j modificada |
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| CA2980751A1 (en) | 2015-03-25 | 2016-09-29 | Stephen F. Carroll | Multi-valent hepatitis b virus antigen binding molecules and uses thereof |
| AU2016249404B2 (en) | 2015-04-17 | 2021-01-21 | Igm Biosciences, Inc. | Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof |
| EP3824903A1 (en) | 2015-09-30 | 2021-05-26 | IGM Biosciences Inc. | Binding molecules with modified j-chain |
| WO2017059387A1 (en) | 2015-09-30 | 2017-04-06 | Igm Biosciences, Inc. | Binding molecules with modified j-chain |
| PT3455257T (pt) | 2016-05-09 | 2021-12-06 | Igm Biosciences Inc | Anticorpos anti-pd-l1 |
| MX388593B (es) | 2016-08-15 | 2025-03-20 | Novartis Ag | Regimenes y metodos de tratamiento de la esclerosis multiple usando ofatumumab. |
| MX2019009468A (es) | 2017-02-08 | 2020-01-20 | Dragonfly Therapeutics Inc | Proteínas de unión multiespecíficas para la activación de células asesinas naturales y usos terapéuticos de las mismas para tratar cáncer. |
| US20200095327A1 (en) * | 2017-02-08 | 2020-03-26 | Dragonfly Therapeutics, Inc. | Antibody heavy chain variable domains targeting the nkg2d receptor |
| FI3582806T3 (fi) | 2017-02-20 | 2023-09-07 | Dragonfly Therapeutics Inc | Her2:ta, nkg2d:tä ja cd16:ta sitovia proteiineja |
| EP3607091A4 (en) | 2017-04-07 | 2021-01-20 | IGM Biosciences, Inc. | HUMAN IGM CONSTANT REGIONS MODIFIED FOR THE MODULATION OF THE COMPLEMENT DEPENDENT CYTOLYTIC EFFECTOR FUNCTION |
| EA202091887A1 (ru) | 2018-02-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры |
| MX2020008336A (es) | 2018-02-08 | 2020-09-21 | Dragonfly Therapeutics Inc | Dominios variables de anticuerpos que se dirigen al receptor nkg2d. |
| MY208785A (en) | 2018-02-20 | 2025-05-28 | Dragonfly Therapeutics Inc | Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use |
| CN111787951B (zh) | 2018-03-01 | 2025-06-17 | Igm生物科学股份有限公司 | 影响IgM血清半衰期的IgM Fc和J链突变 |
| MA53284A (fr) | 2018-08-08 | 2022-01-26 | Dragonfly Therapeutics Inc | Protéines de liaison à nkg2d, à cd16 et à un antigène associé à une tumeur |
| SG11202100883SA (en) | 2018-08-08 | 2021-02-25 | Dragonfly Therapeutics Inc | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| SG11202105010UA (en) * | 2018-11-16 | 2021-06-29 | Memorial Sloan Kettering Cancer Center | Antibodies to mucin-16 and methods of use thereof |
| CA3147291A1 (en) | 2019-08-15 | 2021-02-18 | Igm Biosciences, Inc. | Immunostimulatory multimeric binding molecules |
| CN115836088A (zh) | 2020-05-06 | 2023-03-21 | 蜻蜓疗法股份有限公司 | 结合nkg2d、cd16和clec12a的蛋白质 |
| JP2024500847A (ja) | 2020-12-18 | 2024-01-10 | センチュリー セラピューティクス，インコーポレイテッド | 適合可能な受容体特異性を有するキメラ抗原受容体システム |
| JP2024508894A (ja) | 2021-03-03 | 2024-02-28 | ドラゴンフライ セラピューティクス， インコーポレイテッド | Ｎｋｇ２ｄ、ｃｄ１６、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法 |
| CN114181318B (zh) * | 2021-11-08 | 2023-08-01 | 四川大学 | 一种组织特异性表达穿透血脑屏障的idua融合蛋白的重组腺相关病毒及应用 |
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| CA2863714A1 (en) | 2013-08-15 |
| TWI606064B (zh) | 2017-11-21 |
| BR112014019459B1 (pt) | 2023-04-18 |
| WO2013120012A3 (en) | 2013-11-07 |
| BR112014019459A8 (pt) | 2023-01-10 |
| IN2014MN01781A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-07-03 |
| WO2013120012A2 (en) | 2013-08-15 |
| MX363819B (es) | 2019-04-03 |
| AU2013200903A1 (en) | 2013-08-22 |
| TW201345921A (zh) | 2013-11-16 |
| BR112014019459A2 (pt) | 2017-06-27 |
| US9409976B2 (en) | 2016-08-09 |
| JP2015511817A (ja) | 2015-04-23 |
| DK2812356T3 (da) | 2019-07-08 |
| KR20150001728A (ko) | 2015-01-06 |
| CN104254544A (zh) | 2014-12-31 |
| HK1205136A1 (en) | 2015-12-11 |
| EP2812356A2 (en) | 2014-12-17 |
| ES2735289T3 (es) | 2019-12-17 |
| JP6335796B2 (ja) | 2018-06-06 |
| CA2863714C (en) | 2022-07-05 |
| EP2812356B1 (en) | 2019-03-27 |
| KR102102111B1 (ko) | 2020-04-20 |
| CN104254544B (zh) | 2017-04-26 |
| MX2014009628A (es) | 2015-03-19 |
| US20140044739A1 (en) | 2014-02-13 |
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