ES2588155T3 - Anticuerpo biespecífico de cadena sencilla PSMAxCD3 específico entre especies - Google Patents

Anticuerpo biespecífico de cadena sencilla PSMAxCD3 específico entre especies Download PDF

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Publication number
ES2588155T3
ES2588155T3 ES09783664.7T ES09783664T ES2588155T3 ES 2588155 T3 ES2588155 T3 ES 2588155T3 ES 09783664 T ES09783664 T ES 09783664T ES 2588155 T3 ES2588155 T3 ES 2588155T3
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Prior art keywords
cdr
seq
depicted
single chain
human
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English (en)
Spanish (es)
Inventor
Peter Kufer
Tobias Raum
Roman Kischel
Ralf Lutterbüse
Patrick Hoffmann
Doris Rau
Susanne Mangold
Matthias Klinger
Evelyne Schaller
Susanne Hausmann
Petra Fluhr
Carola Steiger
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Amgen Research Munich GmbH
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Amgen Research Munich GmbH
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES09783664.7T 2008-10-01 2009-10-01 Anticuerpo biespecífico de cadena sencilla PSMAxCD3 específico entre especies Active ES2588155T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US101857P 1998-09-25
US10185708P 2008-10-01 2008-10-01
PCT/EP2009/062793 WO2010037836A2 (en) 2008-10-01 2009-10-01 Cross-species-specific psmaxcd3 bispecific single chain antibody

Publications (1)

Publication Number Publication Date
ES2588155T3 true ES2588155T3 (es) 2016-10-31

Family

ID=42073956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09783664.7T Active ES2588155T3 (es) 2008-10-01 2009-10-01 Anticuerpo biespecífico de cadena sencilla PSMAxCD3 específico entre especies

Country Status (26)

Country Link
US (6) US20110293619A1 (enExample)
EP (3) EP3106468A1 (enExample)
JP (4) JP6126782B2 (enExample)
KR (1) KR101820535B1 (enExample)
CN (1) CN102171248B (enExample)
AU (1) AU2009299792B2 (enExample)
BR (1) BRPI0919841A2 (enExample)
CA (1) CA2738565C (enExample)
CY (1) CY1118303T1 (enExample)
DK (1) DK2356153T3 (enExample)
ES (1) ES2588155T3 (enExample)
HR (1) HRP20160684T1 (enExample)
HU (1) HUE030090T2 (enExample)
IL (1) IL212099A (enExample)
ME (1) ME02485B (enExample)
MX (1) MX2011003502A (enExample)
NZ (1) NZ591134A (enExample)
PL (1) PL2356153T3 (enExample)
PT (1) PT2356153T (enExample)
RS (1) RS54900B1 (enExample)
RU (1) RU2559531C2 (enExample)
SG (1) SG194398A1 (enExample)
SI (1) SI2356153T1 (enExample)
SM (1) SMT201600256B (enExample)
WO (1) WO2010037836A2 (enExample)
ZA (1) ZA201101067B (enExample)

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* Cited by examiner, † Cited by third party
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