JP6126782B2 - 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体 - Google Patents

異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体 Download PDF

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JP6126782B2
JP6126782B2 JP2011529563A JP2011529563A JP6126782B2 JP 6126782 B2 JP6126782 B2 JP 6126782B2 JP 2011529563 A JP2011529563 A JP 2011529563A JP 2011529563 A JP2011529563 A JP 2011529563A JP 6126782 B2 JP6126782 B2 JP 6126782B2
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seq
nos
cdr
single chain
cdrhs
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JP2012504403A5 (enExample
JP2012504403A (ja
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クファー，ペーター
ラウム，トビアス
キッシェル，ロマン
ルッターブゼ，ラルフ
ホフマン，パトリック
ラウ，ドリス
マンゴールド，スザンネ
クリンガー，マティアス
シャーラー，イブリン
ハウスマン，スザンネ
フルール，ペトラ
シュタイガー，カローラ
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Amgen Research Munich GmbH
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Micromet GmbH
Amgen Research Munich GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011529563A 2008-10-01 2009-10-01 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体 Active JP6126782B2 (ja)

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US10185708P 2008-10-01 2008-10-01
US61/101,857 2008-10-01
PCT/EP2009/062793 WO2010037836A2 (en) 2008-10-01 2009-10-01 Cross-species-specific psmaxcd3 bispecific single chain antibody

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JP2012504403A JP2012504403A (ja) 2012-02-23
JP2012504403A5 JP2012504403A5 (enExample) 2013-03-21
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JP2015134815A Active JP6643822B2 (ja) 2008-10-01 2015-07-03 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体
JP2018128072A Pending JP2018198595A (ja) 2008-10-01 2018-07-05 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体
JP2021099390A Active JP7273106B2 (ja) 2008-10-01 2021-06-15 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体

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JP2018128072A Pending JP2018198595A (ja) 2008-10-01 2018-07-05 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体
JP2021099390A Active JP7273106B2 (ja) 2008-10-01 2021-06-15 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体

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KR (1) KR101820535B1 (enExample)
CN (1) CN102171248B (enExample)
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SI (1) SI2356153T1 (enExample)
SM (1) SMT201600256B (enExample)
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2018198595A (ja) * 2008-10-01 2018-12-20 アムゲン リサーチ （ミュンヘン） ゲーエムベーハー 異種間特異的ｐｓｍａ×ｃｄ３二重特異性単鎖抗体

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