ES2550614T3 - Marcadores de expresión génica para predecir la respuesta a la quimioterapia - Google Patents
Marcadores de expresión génica para predecir la respuesta a la quimioterapia Download PDFInfo
- Publication number
- ES2550614T3 ES2550614T3 ES09014283.7T ES09014283T ES2550614T3 ES 2550614 T3 ES2550614 T3 ES 2550614T3 ES 09014283 T ES09014283 T ES 09014283T ES 2550614 T3 ES2550614 T3 ES 2550614T3
- Authority
- ES
- Spain
- Prior art keywords
- dna
- artificial sequence
- synthetic oligonucleotide
- level
- chemotherapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
- G01N2474/20—Immunohistochemistry assay
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56103504P | 2004-04-09 | 2004-04-09 | |
| US561035P | 2004-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2550614T3 true ES2550614T3 (es) | 2015-11-11 |
Family
ID=34981928
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15173816.8T Expired - Lifetime ES2636470T3 (es) | 2004-04-09 | 2005-04-07 | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
| ES09014283.7T Expired - Lifetime ES2550614T3 (es) | 2004-04-09 | 2005-04-07 | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15173816.8T Expired - Lifetime ES2636470T3 (es) | 2004-04-09 | 2005-04-07 | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7871769B2 (cg-RX-API-DMAC7.html) |
| EP (4) | EP2163650B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5813908B2 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2005233593B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2563074C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2163650T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2636470T3 (cg-RX-API-DMAC7.html) |
| IL (4) | IL178508A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005100606A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE529535T1 (de) * | 2002-03-13 | 2011-11-15 | Genomic Health Inc | Genexpressionsprofilierung in einer biopsie unterzogenem tumorgewebe |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| PL3470535T3 (pl) * | 2003-06-24 | 2020-08-24 | Genomic Health, Inc. | Prognozowanie prawdopodobieństwa ponownego wystąpienia raka |
| EP2163650B1 (en) | 2004-04-09 | 2015-08-05 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| JP2007530075A (ja) * | 2004-04-23 | 2007-11-01 | エグザジェン ダイアグノスティクス インコーポレイテッド | 乳がんの予後診断のための組成物および方法 |
| PL1836629T3 (pl) * | 2004-11-05 | 2020-06-15 | Genomic Health, Inc. | Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu |
| WO2006052731A2 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| CA2589918A1 (en) * | 2004-12-08 | 2006-06-15 | Dorre Grueneberg | Method for measuring resistance or sensitivity to docetaxel comprising detection of tacc3 |
| US8133692B2 (en) * | 2005-07-20 | 2012-03-13 | University Of South Florida | Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments |
| EP1937837A2 (en) * | 2005-07-29 | 2008-07-02 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
| WO2007072225A2 (en) * | 2005-12-01 | 2007-06-28 | Medical Prognosis Institute | Methods and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US8445198B2 (en) | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US7892740B2 (en) | 2006-01-19 | 2011-02-22 | The University Of Chicago | Prognosis and therapy predictive markers and methods of use |
| WO2007085497A2 (en) * | 2006-01-30 | 2007-08-02 | Epigenomics Ag | Markers for the prediction of outcome of anthracycline treatment |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Institute, Inc. | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
| JP2008017832A (ja) * | 2006-06-13 | 2008-01-31 | Sysmex Corp | がんの転移の判定方法及び判定装置 |
| DK2081950T3 (da) * | 2006-09-21 | 2013-06-03 | Nuclea Biomarkers Llc | Med irinotecanbehandling forbundne ekspressionsprofiler |
| WO2008058018A2 (en) | 2006-11-02 | 2008-05-15 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| US20110178154A1 (en) * | 2007-02-06 | 2011-07-21 | Birrer Michael J | gene expression profile that predicts ovarian cancer subject response to chemotherapy |
| RS53165B (sr) * | 2007-03-14 | 2014-06-30 | Bionsil S.R.L. | Inhibitori btk za lečenje epitelnih tumora rezistentnih na hemoterapijske lekove |
| CA2680591A1 (en) * | 2007-03-15 | 2008-09-25 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| EP1978106A1 (en) * | 2007-04-07 | 2008-10-08 | Universitätsklinikum Hamburg-Eppendorf | Detection of ESR1 amplification in endometrium cancer and ovary cancer |
| WO2009026128A2 (en) * | 2007-08-16 | 2009-02-26 | Genomic Health, Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| JP2009050189A (ja) * | 2007-08-24 | 2009-03-12 | Sumitomo Bakelite Co Ltd | 抗癌剤の有効性予測方法 |
| AU2008298560A1 (en) * | 2007-09-14 | 2009-03-19 | Ventana Medical Systems, Inc. | Prostate cancer biomarkers |
| JP5303132B2 (ja) * | 2007-09-20 | 2013-10-02 | シスメックス株式会社 | がん細胞の存否を判定する方法及び装置 |
| GB0720113D0 (en) * | 2007-10-15 | 2007-11-28 | Cambridge Cancer Diagnostics L | Diagnostic, prognostic and predictive testing for cancer |
| EP2222875B1 (en) | 2007-11-07 | 2014-08-20 | Genentech, Inc. | Methods and compositions for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
| EP3284828A1 (en) * | 2008-05-07 | 2018-02-21 | Eutropics Pharmaceuticals, Inc. | Antibodies specific to heterodimers of bcl-2 family and uses thereof |
| ES2403220T3 (es) * | 2008-05-12 | 2013-05-16 | Genomic Health, Inc. | Pruebas para predecir la receptividad de pacientes con cáncer a opciones de tratamiento con quimioterapia |
| WO2009143603A1 (en) | 2008-05-28 | 2009-12-03 | Genomedx Biosciences, Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| PL2297359T4 (pl) | 2008-05-30 | 2014-07-31 | Univ North Carolina Chapel Hill | Profile ekspresji genów do przewidywania skutków raka piersi |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| TW201000119A (en) * | 2008-06-10 | 2010-01-01 | Oncotherapy Science Inc | MYBL2 epitope peptides and vaccines containing the same |
| EP2660337B1 (en) * | 2008-07-15 | 2016-09-14 | Epigenomics AG | Method of prediciting the prognosis of a breast cancer therapy based on gene methylation analysis |
| KR100996994B1 (ko) * | 2008-08-18 | 2010-11-25 | 울산대학교 산학협력단 | 간세포암종 수술후 재발 또는 재발 발병 위험성의 진단방법 |
| EP2318553A4 (en) * | 2008-08-20 | 2011-11-02 | Univ Colorado Regents | MARKERS FOR CHECKING THE RECEIVABILITY OF CARCINOMES FOR IGF-1R TREATMENTS |
| JP2010057486A (ja) * | 2008-09-02 | 2010-03-18 | Sysmex Corp | 化学療法に対するがん患者の応答の予測方法 |
| US8583380B2 (en) | 2008-09-05 | 2013-11-12 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| US20130324478A1 (en) * | 2008-09-08 | 2013-12-05 | Laurence Faure | Pharmacodiagnosis Test Targeting Oncology and Neurodegeneration |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| EP3075864A1 (en) * | 2008-10-14 | 2016-10-05 | Caris MPI, Inc. | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| WO2011109440A1 (en) | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings | Biomarkers for theranostics |
| EP2730662A1 (en) | 2008-11-12 | 2014-05-14 | Caris Life Sciences Luxembourg Holdings | Methods and systems of using exosomes for determining phenotypes |
| EP2373809A1 (en) * | 2008-12-10 | 2011-10-12 | Ipsogen | Methods for identifying erbb2 alteration in tumors |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| WO2010091296A2 (en) * | 2009-02-06 | 2010-08-12 | The Regents Of The University Of California | Emx2 in cancer diagnosis and prognosis |
| US8972899B2 (en) | 2009-02-10 | 2015-03-03 | Ayasdi, Inc. | Systems and methods for visualization of data analysis |
| JP5836929B2 (ja) * | 2009-04-18 | 2015-12-24 | ジェネンテック, インコーポレイテッド | 抗cd40抗体を用いる治療に対するb細胞性リンパ腫の応答性を評価するための方法 |
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| NZ705645A (en) | 2010-01-11 | 2016-05-27 | Genomic Health Inc | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| US9469876B2 (en) | 2010-04-06 | 2016-10-18 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for metastatic prostate cancer |
| WO2011135459A2 (en) | 2010-04-29 | 2011-11-03 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy |
| EP2588864A1 (en) * | 2010-07-02 | 2013-05-08 | Topogen Inc. | Method for diagnosis of bladder cancer and related kits |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| SG186953A1 (en) | 2010-07-09 | 2013-02-28 | Somalogic Inc | Lung cancer biomarkers and uses thereof |
| WO2012009347A2 (en) * | 2010-07-12 | 2012-01-19 | Opko Curna Llc | Treatment of bcl2 binding component 3 (bbc3) related diseases by inhibition of natural antisense transcript to bbc3 |
| SG186940A1 (en) | 2010-07-27 | 2013-02-28 | Genomic Health Inc | Method for using gene expression to determine prognosis of prostate cancer |
| US20120040861A1 (en) | 2010-08-13 | 2012-02-16 | Somalogic, Inc. | Pancreatic Cancer Biomarkers and Uses Thereof |
| US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| PT2619576T (pt) | 2010-09-24 | 2020-09-14 | Niels Grabe | Meios e métodos para a previsão de resposta ao tratamento de um paciente com cancro |
| IN2013MN00522A (cg-RX-API-DMAC7.html) | 2010-09-24 | 2015-05-29 | Univ Leland Stanford Junior | |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| JP5828446B2 (ja) * | 2011-02-10 | 2015-12-09 | 国立大学法人秋田大学 | 扁平上皮癌組織の放射線感受性マーカー |
| CA2742342A1 (en) * | 2011-02-12 | 2012-08-12 | Baylor Research Institute | Msh3 expression status determines the responsiveness of cancer cells to the chemotherapeutic treatment with parp inhibitors and platinum drugs |
| EP2705370A2 (en) * | 2011-05-06 | 2014-03-12 | Xentech | Markers for cancer prognosis and therapy and methods of use |
| US10260097B2 (en) | 2011-06-02 | 2019-04-16 | Almac Diagnostics Limited | Method of using a gene expression profile to determine cancer responsiveness to an anti-angiogenic agent |
| WO2012174203A2 (en) * | 2011-06-14 | 2012-12-20 | Anthony Albino | Methods and kits for the detection and treatment of recurring prostate cancer |
| EP2834640B1 (en) * | 2011-10-04 | 2020-06-17 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Cd247 as a biomarker for assessing the effect of chemotherapeutic and biological drugs |
| WO2013055704A1 (en) * | 2011-10-10 | 2013-04-18 | Ayasdi, Inc. | Systems and methods for mapping new patient information to historic outcomes for treatment assistance |
| WO2013082440A2 (en) * | 2011-11-30 | 2013-06-06 | The University Of North Carolina At Chapel Hill | Methods of treating breast cancer with taxane therapy |
| US10513737B2 (en) | 2011-12-13 | 2019-12-24 | Decipher Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| US10519506B2 (en) | 2011-12-22 | 2019-12-31 | Baylor Research Institute | Identification of metastasis-specific miRNA and hypomethylation signatures in human colorectal cancer |
| WO2013109690A1 (en) * | 2012-01-17 | 2013-07-25 | Myriad Genetics, Inc. | Breast cancer prognosis signatures |
| HK1201881A1 (en) | 2012-01-31 | 2015-09-11 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| FR2987446B1 (fr) * | 2012-02-28 | 2016-01-01 | Univ Nice Sophia Antipolis | Test diagnostic de la resistance a l'azacitidine |
| WO2013170174A1 (en) * | 2012-05-10 | 2013-11-14 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Method of diagnosing, treating and determining progression and survival of cancer cells using bcl-2 antagonist of cell death (bad) pathway gene signature |
| US20150133450A1 (en) | 2012-06-20 | 2015-05-14 | Eutropics Pharmaceuticals, Inc. | Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives |
| AU2013302365B2 (en) | 2012-08-16 | 2019-03-21 | Mayo Foundation For Medical Education And Research | Cancer diagnostics using biomarkers |
| CA2891653A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| EP2922544B1 (en) | 2012-11-21 | 2018-08-01 | Eutropics Pharmaceuticals, Inc. | Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives |
| US20140315844A1 (en) * | 2012-11-30 | 2014-10-23 | Celera Corporation | Multi-gene signatures for predicting response to chemotherapy or risk of metastasis for breast cancer |
| SG11201504023SA (en) | 2012-12-03 | 2015-06-29 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| WO2014121177A1 (en) * | 2013-02-01 | 2014-08-07 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Biomarkers and methods for predicting benefit of adjuvant chemotherapy |
| EP2971101A2 (en) | 2013-03-15 | 2016-01-20 | Janssen Pharmaceutica N.V. | Assay for predictive biomarkers |
| WO2014194078A1 (en) * | 2013-05-30 | 2014-12-04 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
| US10732182B2 (en) | 2013-08-01 | 2020-08-04 | Eutropics Pharmaceuticals, Inc. | Method for predicting cancer sensitivity |
| US10640803B2 (en) | 2013-10-30 | 2020-05-05 | Eutropics Pharmaceuticals, Inc. | Methods for determining chemosensitivity and chemotoxicity |
| GB201409479D0 (en) | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| SI3134119T1 (sl) * | 2014-04-24 | 2018-11-30 | Pfizer Inc. | Zdravljenje raka |
| EP3143160B1 (en) | 2014-05-13 | 2019-11-06 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| CN104004844A (zh) * | 2014-05-28 | 2014-08-27 | 杭州美中疾病基因研究院有限公司 | 乳腺癌21基因联合检测试剂盒及其制备方法 |
| DK3198035T3 (da) | 2014-09-26 | 2023-01-30 | Allarity Therapeutics Europe ApS | Fremgangsmåder til forudsigelse af medicinrespons |
| US10670611B2 (en) | 2014-09-26 | 2020-06-02 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| AU2015334841B2 (en) * | 2014-10-24 | 2022-02-03 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| JP7065610B6 (ja) * | 2014-10-24 | 2022-06-06 | コーニンクレッカ フィリップス エヌ ヴェ | 複数の細胞シグナル伝達経路活性を用いる治療応答の医学的予後及び予測 |
| WO2016115105A1 (en) | 2015-01-12 | 2016-07-21 | Eutropics Pharmaceuticals, Inc. | Context dependent diagnostics test for guiding cancer treatment |
| CN107548498A (zh) | 2015-01-20 | 2018-01-05 | 南托米克斯有限责任公司 | 用于反应预测高级别膀胱癌中的化疗的系统和方法 |
| SG10202104058XA (en) | 2015-10-14 | 2021-05-28 | Bio Path Holdings Inc | P-ethoxy nucleic acids for liposomal formulation |
| WO2017096458A1 (en) * | 2015-12-07 | 2017-06-15 | Ontario Institute For Cancer Research (Oicr) | Immune gene signature predictive of anthracycline benefit |
| WO2017100732A1 (en) * | 2015-12-10 | 2017-06-15 | Nantomics, Llc | Integrated analysis to determine prognosis after treatment for primary breast cancer |
| CN110506127B (zh) | 2016-08-24 | 2024-01-12 | 维拉科特Sd公司 | 基因组标签预测前列腺癌患者对术后放射疗法应答性的用途 |
| MX2019003070A (es) | 2016-09-16 | 2019-10-14 | Bio Path Holdings Inc | Terapia de combinacion con oligonucleotidos antisentido liposomales. |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| CA3050984A1 (en) | 2017-01-20 | 2018-07-26 | Decipher Biosciences, Inc. | Molecular subtyping, prognosis, and treatment of bladder cancer |
| US11873532B2 (en) | 2017-03-09 | 2024-01-16 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| US11746381B2 (en) | 2017-03-10 | 2023-09-05 | Cancer Diagnostics Research Innvovations, LLC | Methods for diagnosing and treating gastric cancer using miRNA expression |
| EP3612160A4 (en) | 2017-04-19 | 2021-01-20 | Bio-Path Holdings, Inc. | P-ETHOXY NUCLEIC ACIDS TO INHIBIT BCL2 |
| IL269608B2 (en) | 2017-04-19 | 2024-06-01 | Bio Path Holdings Inc | Compositions comprising p-ethoxy nucleic acids for stat3 inhibition for use in treating cancer or autoimmune disease |
| CA3062716A1 (en) | 2017-05-12 | 2018-11-15 | Decipher Biosciences, Inc. | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| US12497660B2 (en) | 2017-08-04 | 2025-12-16 | Veracyte SD, Inc. | Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy |
| RU2675236C1 (ru) * | 2018-02-22 | 2018-12-18 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ прогнозирования развития метастазов у больных раком молочной железы |
| KR102767594B1 (ko) * | 2018-07-12 | 2025-02-12 | 코버스 파마슈티칼스, 인크. | 아데노신 경로 활성화를 갖는 암의 검출 및 치료 방법 |
| US20220357328A1 (en) * | 2019-09-09 | 2022-11-10 | Oaklabs Gmbh | Superior biomarker signature to predict the response of a breast cancer patient to chemotherapy |
| CN111184865B (zh) * | 2020-03-09 | 2021-11-16 | 复旦大学附属金山医院 | Stat1在耐紫杉醇上皮性卵巢癌治疗中的用途 |
| GB202116745D0 (en) * | 2021-11-19 | 2022-01-05 | Institute Of Cancer Res Royal Cancer Hospital | Prognostic and treatment response predictive method |
| WO2024112609A1 (en) * | 2022-11-21 | 2024-05-30 | Merck Sharp & Dohme Llc | Genome wide tumor derived gene expression based signatures associated with poor prognosis for melanoma patients with early stage disease |
Family Cites Families (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE35491E (en) | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| IE56509B1 (en) | 1982-11-04 | 1991-08-28 | Univ California | Methods for oncogenic detection |
| US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US7838216B1 (en) * | 1986-03-05 | 2010-11-23 | The United States Of America, As Represented By The Department Of Health And Human Services | Human gene related to but distinct from EGF receptor gene |
| US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| US5202429A (en) * | 1986-07-09 | 1993-04-13 | The Wistar Institute | DNA molecules having human BCL-2 gene sequences |
| US4968603A (en) * | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
| US5831066A (en) * | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| US5858678A (en) * | 1994-08-02 | 1999-01-12 | St. Louis University | Apoptosis-regulating proteins |
| US5830753A (en) * | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| US6716575B2 (en) * | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| AU716330B2 (en) * | 1995-12-18 | 2000-02-24 | Sugen, Inc. | Diagnosis and treatment of AUR-1 and/or AUR-2 related disorders |
| US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
| US5821082A (en) * | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
| US5952178A (en) * | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
| US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
| US6143529A (en) * | 1996-08-14 | 2000-11-07 | Exact Laboratories, Inc. | Methods for improving sensitivity and specificity of screening assays |
| US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| US6203993B1 (en) * | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
| US5861278A (en) * | 1996-11-01 | 1999-01-19 | Genetics Institute, Inc. | HNF3δ compositions |
| AU736587B2 (en) * | 1996-11-20 | 2001-08-02 | Yale University | Survivin, a protein that inhibits cellular apoptosis, and its modulation |
| US5830665A (en) * | 1997-03-03 | 1998-11-03 | Exact Laboratories, Inc. | Contiguous genomic sequence scanning |
| US6033893A (en) * | 1997-06-26 | 2000-03-07 | Incyte Pharmaceuticals, Inc. | Human cathepsin |
| WO1999002714A1 (en) | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
| US6020135A (en) * | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| GB2339200B (en) * | 1998-06-06 | 2001-09-12 | Genostic Pharma Ltd | Genostics |
| US6696558B2 (en) * | 1998-09-09 | 2004-02-24 | The Burnham Institute | Bag proteins and nucleic acid molecules encoding them |
| WO2000022093A2 (en) | 1998-09-23 | 2000-04-20 | Cleveland Clinic Foundation | Novel interferon stimulated and repressed genes |
| AU1853600A (en) | 1999-01-06 | 2000-07-24 | Choong-Chin Liew | Method for the detection of gene transcripts in blood and uses thereof |
| WO2000050595A2 (en) | 1999-02-25 | 2000-08-31 | Ivan Gout | Nucleic acid molecules associated with melanoma and thyroid tumors |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US20020039764A1 (en) * | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| DE19922052A1 (de) * | 1999-05-14 | 2000-11-16 | Theragen Molekularmedizinische | Verfahren zum Nachweis der Wirkung von unterschiedlichen Chemotherapeutika und/oder einer Strahlentherapie bei malignen Erkrankungen sowie Verfahren zur Auswahl wirkungsvoller therapeutischer Mittel zu deren Therapie |
| US6692916B2 (en) * | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6960439B2 (en) * | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
| US6710170B2 (en) * | 1999-09-10 | 2004-03-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US6271002B1 (en) * | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
| EP1218394A4 (en) | 1999-10-06 | 2004-04-14 | Univ California | DIFFERENTIAL EXPRESSION GENES ASSOCIATED WITH OVER-EXPRESSION OF HER-2 / NEU |
| CA2490909A1 (en) | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6750013B2 (en) * | 1999-12-02 | 2004-06-15 | Protein Design Labs, Inc. | Methods for detection and diagnosing of breast cancer |
| US6248535B1 (en) * | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| AU2001232485A1 (en) * | 2000-01-13 | 2001-07-24 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
| US6322986B1 (en) * | 2000-01-18 | 2001-11-27 | Albany Medical College | Method for colorectal cancer prognosis and treatment selection |
| AU2001234608A1 (en) * | 2000-01-28 | 2001-08-07 | Genetrace Systems, Inc. | Methods for analysis of gene expression |
| WO2001055447A1 (en) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| AU4592601A (en) | 2000-03-21 | 2001-10-03 | Millennium Predictive Medicine | Novel genes, compositions, kits, and method for identification, assessment, prevention, and therapy of ovarian cancer |
| WO2001075159A2 (en) * | 2000-03-31 | 2001-10-11 | Sir Mortimer B. Davis Jewish General Hospital | Microchip arrays of regulatory genes |
| WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20030165952A1 (en) * | 2000-07-21 | 2003-09-04 | Sten Linnarsson | Method and an alggorithm for mrna expression analysis |
| AU2001278011A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ecg1 protein and related reagents and methods of use thereof |
| AU2001278076A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-5 proteins and related reagents and methods of use thereof |
| WO2002008282A2 (en) | 2000-07-26 | 2002-01-31 | Stanford University | Bstp-ras/rerg protein and related reagents and methods of use thereof |
| WO2002010436A2 (en) | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
| US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| AU2002214576A1 (en) | 2000-10-13 | 2002-04-22 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genes related to development of refractory prostate cancer |
| US6602670B2 (en) * | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US6582919B2 (en) * | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
| EP1353947A2 (en) * | 2000-12-08 | 2003-10-22 | Ipsogen | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| JP4368110B2 (ja) * | 2001-01-12 | 2009-11-18 | エール ユニヴァーシティ | 癌患者の生物学的流体中のサバイビンの検出 |
| US7776518B2 (en) * | 2001-01-12 | 2010-08-17 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| WO2002059377A2 (en) | 2001-01-24 | 2002-08-01 | Protein Design Labs | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
| EP1379694B1 (en) * | 2001-03-01 | 2006-05-10 | Epigenomics AG | Methods and computer program products for determining the biological effect and/or activity of drugs, chemical substances and/or pharmaceutical compositions based on their effect on the methylation status of the dna |
| US6939670B2 (en) | 2001-03-12 | 2005-09-06 | Monogen, Inc. | Cell-based detection and differentiation of lung cancer |
| US20030077582A1 (en) * | 2001-03-27 | 2003-04-24 | Wen-Lin Kuo | Methods for diagnosing and monitoring malignancies by screeining gene copy numbers |
| US6686155B2 (en) * | 2001-06-14 | 2004-02-03 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression |
| US7171311B2 (en) * | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
| US7514209B2 (en) | 2001-06-18 | 2009-04-07 | Rosetta Inpharmatics Llc | Diagnosis and prognosis of breast cancer patients |
| WO2003011897A1 (en) | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Modulation of heregulin and her3 interaction |
| WO2003029273A2 (en) * | 2001-09-28 | 2003-04-10 | Whitehead Institute For Biomedical Research | Classification of lung carcinomas using gene expression analysis |
| CN102402650A (zh) * | 2001-11-09 | 2012-04-04 | 生命技术公司 | 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态 |
| US20030198972A1 (en) * | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| US20030124130A1 (en) * | 2002-01-02 | 2003-07-03 | Brown Robert E. | Proteomic analysis of tumors for development of consultative report of therapeutic options |
| EP1466016A2 (en) * | 2002-01-09 | 2004-10-13 | Riken Institute Of Physical And Chemical Research | Cancer profiles |
| US7704700B2 (en) * | 2002-02-12 | 2010-04-27 | Burnham Institute For Medical Research | Methods for determining the prognosis for patients with a prostate neoplastic condition using inhibitor of apoptosis polypeptides |
| ATE529535T1 (de) * | 2002-03-13 | 2011-11-15 | Genomic Health Inc | Genexpressionsprofilierung in einer biopsie unterzogenem tumorgewebe |
| WO2003083096A2 (en) | 2002-03-28 | 2003-10-09 | Qlt Inc. | Cancer associated protein kinases and their uses |
| US20050272052A1 (en) | 2002-04-09 | 2005-12-08 | Affymetrix, Inc. | Molecular genetic profiling of gleason grades 3 and 4/5 prostate cancer |
| EP1365034A3 (en) | 2002-05-21 | 2004-02-18 | Bayer HealthCare AG | Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| JP4568716B2 (ja) | 2003-02-20 | 2010-10-27 | ジェノミック ヘルス, インコーポレイテッド | 遺伝子発現を測定するためのイントロンrnaの使用 |
| WO2004111603A2 (en) | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| PL3470535T3 (pl) | 2003-06-24 | 2020-08-24 | Genomic Health, Inc. | Prognozowanie prawdopodobieństwa ponownego wystąpienia raka |
| EP3330875B1 (en) * | 2003-07-10 | 2021-12-01 | Genomic Health, Inc. | Expression profile algorithm and test for prognosing breast cancer recurrence |
| WO2005015236A2 (en) | 2003-07-18 | 2005-02-17 | Roche Diagnostics Gmbh | A method for predicting the progression of adenocarcinoma |
| EP1522594A3 (en) | 2003-10-06 | 2005-06-22 | Bayer HealthCare AG | Methods and kits for investigating cancer |
| EP2163650B1 (en) | 2004-04-09 | 2015-08-05 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| CA2992180C (en) | 2004-05-07 | 2021-02-23 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer |
| WO2005118858A1 (en) * | 2004-05-28 | 2005-12-15 | Board Of Regents, The University Of Texas System | Multigene predictors of response to chemotherapy |
| PL1836629T3 (pl) * | 2004-11-05 | 2020-06-15 | Genomic Health, Inc. | Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu |
| WO2006052731A2 (en) | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| ES2624863T3 (es) | 2005-06-08 | 2017-07-17 | Millennium Pharmaceuticals, Inc. | Métodos para identificación, evaluación, y tratamiento de pacientes con terapia de cáncer |
| AU2006259583A1 (en) | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US20070099209A1 (en) | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| NZ544432A (en) | 2005-12-23 | 2009-07-31 | Pacific Edge Biotechnology Ltd | Prognosis prediction for colorectal cancer using a prognositc signature comprising markers ME2 and FAS |
| EP2412821B1 (en) | 2006-01-11 | 2014-09-17 | Genomic Health, Inc. | AREG as a gene expression marker for colorectal cancer prognosis |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| CA2680591A1 (en) | 2007-03-15 | 2008-09-25 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| WO2009026128A2 (en) | 2007-08-16 | 2009-02-26 | Genomic Health, Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| WO2009114836A1 (en) | 2008-03-14 | 2009-09-17 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| ES2403220T3 (es) | 2008-05-12 | 2013-05-16 | Genomic Health, Inc. | Pruebas para predecir la receptividad de pacientes con cáncer a opciones de tratamiento con quimioterapia |
| CA2742489A1 (en) | 2008-11-14 | 2010-05-20 | Intelligent Oncotherapeutics, Inc. | Methods for identification of tumor phenotype and treatment |
| US20110236903A1 (en) | 2008-12-04 | 2011-09-29 | Mcclelland Michael | Materials and methods for determining diagnosis and prognosis of prostate cancer |
| NZ596054A (en) | 2009-05-01 | 2013-07-26 | Genomic Health Inc | Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy |
| AU2010321829B2 (en) | 2009-11-23 | 2015-07-30 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
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