MX351626B - Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata. - Google Patents

Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Info

Publication number
MX351626B
MX351626B MX2014009283A MX2014009283A MX351626B MX 351626 B MX351626 B MX 351626B MX 2014009283 A MX2014009283 A MX 2014009283A MX 2014009283 A MX2014009283 A MX 2014009283A MX 351626 B MX351626 B MX 351626B
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MX
Mexico
Prior art keywords
prostate cancer
test
gene expression
expression profile
determining prognosis
Prior art date
Application number
MX2014009283A
Other languages
English (en)
Other versions
MX2014009283A (es
Inventor
Maddala Tara
J Pelham Robert
Crager Michael
Shak Steve
Lee Mark
Novotny William
Cherbavaz Diana
L Millward Carl
Knezevic Dejan
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of MX2014009283A publication Critical patent/MX2014009283A/es
Publication of MX351626B publication Critical patent/MX351626B/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Complex Calculations (AREA)

Abstract

La presente invención se refiere a ensayos moleculares basados en algoritmo que implica en la medición de los niveles de expresión de los genes, o sus genes co-expresados, de una muestra biológica obtenida de un paciente con cáncer de próstata. Los genes se pueden agrupar en subconjuntos de genes funcionales para calcular un registro cuantitativo útil para predecir una probabilidad de un resultado clínico para un paciente con cáncer de próstata.
MX2014009283A 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata. MX351626B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261593106P 2012-01-31 2012-01-31
US201261672679P 2012-07-17 2012-07-17
US201261713734P 2012-10-15 2012-10-15
PCT/US2013/023409 WO2013116144A1 (en) 2012-01-31 2013-01-28 Gene expression profile algorithm and test for determining prognosis of prostate cancer

Publications (2)

Publication Number Publication Date
MX2014009283A MX2014009283A (es) 2014-09-11
MX351626B true MX351626B (es) 2017-10-23

Family

ID=48870540

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2017013491A MX366164B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
MX2014009283A MX351626B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
MX2019007814A MX2019007814A (es) 2012-01-31 2014-07-31 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Family Applications Before (1)

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MX2017013491A MX366164B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Family Applications After (1)

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MX2019007814A MX2019007814A (es) 2012-01-31 2014-07-31 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Country Status (14)

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US (3) US8725426B2 (es)
EP (3) EP2809812A4 (es)
JP (3) JP6351112B2 (es)
AU (3) AU2013215448B2 (es)
CA (1) CA2863040C (es)
CO (1) CO7051010A2 (es)
DK (1) DK3179393T3 (es)
ES (1) ES2812105T3 (es)
HK (1) HK1201881A1 (es)
IL (3) IL233709A (es)
MX (3) MX366164B (es)
NZ (2) NZ722902A (es)
SG (3) SG10201605210PA (es)
WO (1) WO2013116144A1 (es)

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JP2015511814A (ja) 2015-04-23
SG10201912312YA (en) 2020-02-27
JP2019013255A (ja) 2019-01-31
IL262648A (en) 2018-12-31
HK1201881A1 (en) 2015-09-11
MX2019007814A (es) 2019-09-05
US20140303002A1 (en) 2014-10-09
MX366164B (es) 2019-07-01
JP6351112B2 (ja) 2018-07-04
EP2809812A1 (en) 2014-12-10
EP3179393B1 (en) 2020-07-08
ES2812105T3 (es) 2021-03-16
AU2013215448B2 (en) 2018-01-04
CA2863040A1 (en) 2013-08-08
US8725426B2 (en) 2014-05-13
NZ722902A (en) 2017-12-22
CO7051010A2 (es) 2014-09-10
AU2018201688A1 (en) 2018-04-05
IL262648B (en) 2020-07-30
US20130196321A1 (en) 2013-08-01
EP3179393A2 (en) 2017-06-14
IL254255B (en) 2018-11-29
EP2809812A4 (en) 2016-01-27
AU2018201688B2 (en) 2020-02-27
IL233709A (en) 2017-09-28
EP3179393A3 (en) 2017-09-13
JP6908571B2 (ja) 2021-07-28
SG11201404390WA (en) 2014-08-28
AU2020202164B2 (en) 2022-02-10
DK3179393T3 (da) 2020-07-27
IL254255A0 (en) 2017-10-31
NZ627887A (en) 2016-08-26
CA2863040C (en) 2022-04-19
EP3739595A2 (en) 2020-11-18
AU2013215448A1 (en) 2014-08-21
US11011252B1 (en) 2021-05-18
EP3739595A3 (en) 2021-01-27
SG10201605210PA (en) 2016-08-30
WO2013116144A1 (en) 2013-08-08
AU2020202164A1 (en) 2020-04-16
IL233709A0 (en) 2014-09-30
MX2014009283A (es) 2014-09-11
JP2017113008A (ja) 2017-06-29

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