MX366164B - Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata. - Google Patents

Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Info

Publication number
MX366164B
MX366164B MX2017013491A MX2017013491A MX366164B MX 366164 B MX366164 B MX 366164B MX 2017013491 A MX2017013491 A MX 2017013491A MX 2017013491 A MX2017013491 A MX 2017013491A MX 366164 B MX366164 B MX 366164B
Authority
MX
Mexico
Prior art keywords
prostate cancer
test
gene expression
expression profile
determining prognosis
Prior art date
Application number
MX2017013491A
Other languages
English (en)
Inventor
J Pelham Robert
Crager Michael
Shak Steve
Lee Mark
Novotny William
Cherbavaz Diana
L Millward Carl
Knezevic Dejan
Maddala Tara
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of MX366164B publication Critical patent/MX366164B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Complex Calculations (AREA)

Abstract

La presente invención se refiere a ensayos moleculares basados en algoritmo que implica en la medición de los niveles de expresión de los genes, o sus genes co-expresados, de una muestra biológica obtenida de un paciente con cáncer de próstata. Los genes se pueden agrupar en subconjuntos de genes funcionales para calcular un registro cuantitativo útil para predecir una probabilidad de un resultado clínico para un paciente con cáncer de próstata.
MX2017013491A 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata. MX366164B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261593106P 2012-01-31 2012-01-31
US201261672679P 2012-07-17 2012-07-17
US201261713734P 2012-10-15 2012-10-15

Publications (1)

Publication Number Publication Date
MX366164B true MX366164B (es) 2019-07-01

Family

ID=48870540

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2014009283A MX351626B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
MX2017013491A MX366164B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
MX2019007814A MX2019007814A (es) 2012-01-31 2014-07-31 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2014009283A MX351626B (es) 2012-01-31 2013-01-28 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019007814A MX2019007814A (es) 2012-01-31 2014-07-31 Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.

Country Status (14)

Country Link
US (3) US8725426B2 (es)
EP (3) EP2809812A4 (es)
JP (3) JP6351112B2 (es)
AU (3) AU2013215448B2 (es)
CA (1) CA2863040C (es)
CO (1) CO7051010A2 (es)
DK (1) DK3179393T3 (es)
ES (1) ES2812105T3 (es)
HK (1) HK1201881A1 (es)
IL (3) IL233709A (es)
MX (3) MX351626B (es)
NZ (2) NZ722902A (es)
SG (3) SG10201912312YA (es)
WO (1) WO2013116144A1 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2809812A4 (en) * 2012-01-31 2016-01-27 Genomic Health Inc GENE EXPRESSION PROFILE ALGORITHM AND PROSTATE CANCER PROGNOSTIC DETERMINATION TEST
US11035005B2 (en) 2012-08-16 2021-06-15 Decipher Biosciences, Inc. Cancer diagnostics using biomarkers
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
CN105849555B (zh) * 2013-12-18 2019-05-14 加利福尼亚太平洋生物科学股份有限公司 用于错误校正的序列读数迭代聚类
CN103695560B (zh) * 2014-01-09 2016-09-14 上海交通大学医学院附属瑞金医院 Ppp1r12a基因在结直肠癌化疗疗效判断和检测试剂盒中的应用
CN105917008B (zh) * 2014-01-16 2020-11-27 启迪公司 用于前列腺癌复发的预后的基因表达面板
WO2015131177A1 (en) * 2014-02-28 2015-09-03 The Johns Hopkins University Genes encoding secreted proteins which identify clinically significant prostate cancer
EP3623482A1 (en) * 2014-05-13 2020-03-18 Myriad Genetics, Inc. Gene signatures for cancer prognosis
EP3210144B1 (en) 2014-10-24 2020-10-21 Koninklijke Philips N.V. Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities
JP7065609B6 (ja) 2014-10-24 2022-06-06 コーニンクレッカ フィリップス エヌ ヴェ 複数の細胞シグナル伝達経路活性を用いる治療応答の医学的予後及び予測
BR112017007965A8 (pt) 2014-10-24 2022-11-08 Koninklijke Philips Nv Método implantado por computador para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; aparelho para inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; meio de armazenamento não transitório; programa de computador; kits para medir níveis de expressão de três ou mais genes-alvo da via de sinalização celular de tgf-b em uma amostra de um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; inferir a atividade de uma via de sinalização celular de tgf-b em um indivíduo; e uso do kit
CN104880565A (zh) * 2015-05-04 2015-09-02 贵州省人民医院 Zfp36前列腺癌预后诊断的检测试剂及其试剂盒
BR112017025255B1 (pt) * 2015-05-29 2024-02-27 Koninklijke Philips N.V Método implementado por computador, método e composição farmacêutica inibidora
DK3303618T3 (da) * 2015-05-29 2019-12-16 Koninklijke Philips Nv Fremgangsmåder til prognose af prostatacancer
CN107849556A (zh) * 2015-07-01 2018-03-27 学校法人庆应义塾 癌组织的异质性标记物及其使用
CA2995520A1 (en) 2015-08-14 2017-02-23 Hendrik Jan VAN OOIJEN Assessment of nfkb cellular signaling pathway activity using mathematical modelling of target gene expression
EP3359692A4 (en) * 2015-10-05 2019-05-01 Cedars-Sinai Medical Center METHOD FOR CLASSIFYING AND TREATING CANCER
EP3405583B1 (en) * 2016-01-20 2024-04-03 Dana-Farber Cancer Institute, Inc. Compositions and methods for screening and identifying clinically aggressive prostate cancer
DK3270163T3 (en) * 2016-07-15 2018-11-19 Proteomedix Ag PROCEDURE FOR DETECTING PROTEINS IN HUMAN SAMPLES AND APPLICATIONS OF SUCH PROCEDURES
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
US11586674B2 (en) * 2016-12-28 2023-02-21 Khalifa University of Science and Technology Methods and systems for searching
CA3049844C (en) * 2017-02-13 2022-06-28 Genomic Health, Inc. Algorithms and methods for assessing late clinical endpoints in prostate cancer
EP3593140A4 (en) * 2017-03-09 2021-01-06 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
EP4428157A3 (en) 2017-08-04 2024-12-11 Veracyte SD, Inc. Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy
EP3461916A1 (en) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Assessment of jak-stat3 cellular signaling pathway activity using mathematical modelling of target gene expression
EP3461915A1 (en) 2017-10-02 2019-04-03 Koninklijke Philips N.V. Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression
US20200294617A1 (en) * 2017-10-27 2020-09-17 King Abdullah University Of Science And Technology A graph-based constant-column biclustering device and method for mining growth phenotype data
EP3502279A1 (en) 2017-12-20 2019-06-26 Koninklijke Philips N.V. Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression
EP3502280A1 (en) 2017-12-21 2019-06-26 Koninklijke Philips N.V. Pre-surgical risk stratification based on pde4d7 expression and pre-surgical clinical variables
US12123058B2 (en) 2018-01-25 2024-10-22 Sorbonne Universite Molecular signature and use thereof for the identification of indolent prostate cancer
EP3755816B1 (en) * 2018-02-22 2025-02-12 Liquid Biopsy Research LLC Methods for prostate cancer detection and treatment
CA3003032A1 (en) * 2018-04-27 2019-10-27 Nanostics Inc. Methods of diagnosing disease using microflow cytometry
CN109001467A (zh) * 2018-07-20 2018-12-14 贵州省人民医院 一种用于前列腺癌的基因联合预后检测试剂及其制备方法
GB201816820D0 (en) * 2018-10-16 2018-11-28 Univ York Diagnostic method
US12325879B2 (en) 2018-10-31 2025-06-10 Regents Of The University Of Minnesota Methods for predicting a response to bevacizumab or platinum-based chemotherapy or both in patients with ovarian cancer
MX2022001812A (es) 2019-08-12 2022-03-11 Regeneron Pharma Variantes del receptor estimulante de macrofagos 1 (mst1r) y sus usos.
EP3901288A1 (en) * 2020-04-20 2021-10-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Multi-gene expression assay for prostate carcinoma

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4158799A (en) 1998-06-06 1999-12-30 Genostic Pharma Limited Probes used for genetic filing
CA2330929A1 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
WO2000040749A2 (en) 1999-01-06 2000-07-13 Genenews Inc. Method for the detection of gene transcripts in blood and uses thereof
FI990382A0 (fi) 1999-02-23 1999-02-23 Arctic Partners Oy Ab Uusi diagnostinen menetelmä
US6692916B2 (en) 1999-06-28 2004-02-17 Source Precision Medicine, Inc. Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
AU785055B2 (en) 2000-01-13 2006-09-07 Genentech Inc. Novel stra6 polypeptides
WO2002031209A2 (en) 2000-10-13 2002-04-18 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Genes related to development of refractory prostate cancer
US20030087818A1 (en) 2001-02-02 2003-05-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
CA2442820A1 (en) 2001-03-29 2002-10-10 Van Andel Institute Microarray gene expression profiling in clear cell renal cell carcinoma: prognosis and drug target identification
US20030108963A1 (en) 2001-07-25 2003-06-12 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer
US20100297657A1 (en) 2001-08-02 2010-11-25 The Regents Of The University Of Michigan Expression profile of prostate cancer
JP5236856B2 (ja) 2001-11-09 2013-07-17 ライフ テクノロジーズ コーポレーション 遺伝子発現プロファイルを用いる病気の同定、観測及び治療及び生物学的状態の同定
WO2003050243A2 (en) 2001-12-10 2003-06-19 Millennium Pharmaceuticals Inc. Novel genes encoding colon cancer antigens
US6949342B2 (en) * 2001-12-21 2005-09-27 Whitehead Institute For Biomedical Research Prostate cancer diagnosis and outcome prediction by expression analysis
AU2003242820A1 (en) 2002-03-14 2003-09-22 Exonhit Therapeutics S.A. Variants of human kallikrein-2 and kallikrein-3 and uses thereof
AUPS187002A0 (en) 2002-04-22 2002-05-30 Queensland University Of Technology Condition-specific molecules and uses therefor
CA2498418A1 (en) 2002-09-10 2004-03-25 Guennadi V. Glinskii Gene segregation and biological sample classification methods
US7659062B2 (en) 2003-06-03 2010-02-09 The Board of Trustee of the University of Arkansas System Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors
DK1644858T3 (da) 2003-07-10 2018-01-22 Genomic Health Inc Funktionel beklædning med mindst et yderlag og en indermembran.
WO2005007830A2 (en) * 2003-07-14 2005-01-27 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
JP2007507204A (ja) 2003-07-29 2007-03-29 ブリストル−マイヤーズ スクイブ カンパニー サイクリン依存性キナーゼモデュレーションのバイオマーカー
JP2005211023A (ja) 2004-01-30 2005-08-11 Hayashibara Biochem Lab Inc 腎細胞癌の転移若しくは再発の可能性を予測する方法
WO2005076005A2 (en) 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
CA2848463A1 (en) 2004-04-09 2005-10-27 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US20070224596A1 (en) 2004-04-09 2007-09-27 Mariana Nacht Compositions and methods for the modifying hypoxia induced gene regulation
CA2565450C (en) 2004-05-07 2018-03-06 Gyorgy Petrovics Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer
EP1766091A4 (en) 2004-05-27 2009-03-18 Vertex Pharma BIOMARKER FOR MONITORING THE INHIBITION OF THE IMPDH PATH
US7587279B2 (en) 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
EP1784511A4 (en) 2004-08-13 2009-03-11 Millennium Pharm Inc GENES, COMPOSITIONS, KITS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF PROSTATE CANCER
WO2006091776A2 (en) 2005-02-25 2006-08-31 The Brigham And Women's Hospital, Inc. Biomarkers for predicting prostate cancer progression
US8349555B2 (en) 2005-03-16 2013-01-08 Gennadi V. Glinsky Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures
US20090186024A1 (en) 2005-05-13 2009-07-23 Nevins Joseph R Gene Expression Signatures for Oncogenic Pathway Deregulation
JP5904569B2 (ja) 2005-06-08 2016-04-13 ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. 癌治療を受けている患者の同定、判定および処置のための方法
WO2006138275A2 (en) 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
AU2006287175A1 (en) 2005-09-01 2007-03-08 Precision Therapeutics, Inc. Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics
CA2622295C (en) 2005-09-12 2019-01-15 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
EP1960551A2 (en) 2005-12-01 2008-08-27 Medical Prognosis Institute Methods and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8445198B2 (en) 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US20090215054A1 (en) 2005-12-13 2009-08-27 Carter Scott L Prognosis indicators for solid human tumors
NZ593225A (en) 2006-01-11 2012-10-26 Genomic Health Inc Gene expression markers (CMYC and Ki-67) for colorectal cancer prognosis
ES2300176B1 (es) 2006-02-15 2009-05-01 Consejo Superior Investig. Cientificas Metodo para el diagnostico molecular de cancer de prostata, kit para implementar el metodo.
US7914988B1 (en) * 2006-03-31 2011-03-29 Illumina, Inc. Gene expression profiles to predict relapse of prostate cancer
US7888019B2 (en) 2006-03-31 2011-02-15 Genomic Health, Inc. Genes involved estrogen metabolism
EP2029020A4 (en) 2006-06-22 2010-04-21 Wisconsin Alumni Res Found USE OF STROMA COLLAGEN IN THE DIAGNOSIS AND CHARACTERIZATION OF BREAST CANCER
WO2008067065A2 (en) 2006-10-19 2008-06-05 Shiv Srivastava Methods, kits, and systems for diagnosing and prognosing prostate cancer using secreted biomarkers
WO2008061104A2 (en) * 2006-11-13 2008-05-22 Invitrogen Corporation Methods and kits for detecting prostate cancer biomarkers
CA2680591A1 (en) 2007-03-15 2008-09-25 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
US8835480B2 (en) * 2007-04-23 2014-09-16 California Institute Of Technology Inhibitors for steroid response elements and related methods
US20090123439A1 (en) 2007-11-09 2009-05-14 The Jackson Laboratory Diagnostic and prognosis methods for cancer stem cells
US8067178B2 (en) 2008-03-14 2011-11-29 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
AU2009253675A1 (en) * 2008-05-28 2009-12-03 Genomedx Biosciences, Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US20090298082A1 (en) * 2008-05-30 2009-12-03 Klee George G Biomarker panels for predicting prostate cancer outcomes
KR20110052627A (ko) 2008-07-16 2011-05-18 다나-파버 캔서 인스티튜트 인크. 전립선암과 관련된 시그너처 및 pc결정인자 및 그의 사용 방법
WO2010056993A2 (en) 2008-11-14 2010-05-20 Emory University Prostate cancer biomarkers to predict recurrence and metastatic potential
EP2370813A4 (en) 2008-12-04 2012-05-23 Univ California MATERIALS AND METHODS FOR DIAGNOSIS AND PRESENTATION OF PROSTATE CANCER
CA2749103A1 (en) 2009-01-07 2010-07-15 Steve Stone Cancer biomarkers
US8765383B2 (en) 2009-04-07 2014-07-01 Genomic Health, Inc. Methods of predicting cancer risk using gene expression in premalignant tissue
US20100303795A1 (en) 2009-05-27 2010-12-02 Soerensen Karina Dalsgaard Marker of prostate cancer
WO2011003911A1 (en) 2009-07-08 2011-01-13 Vladimir Lazar Method for predicting efficacy of drugs in a patient
EP4350001A3 (en) 2009-11-23 2024-06-19 Genomic Health, Inc. Methods to predict clinical outcome of cancer
NZ719474A (en) 2010-01-11 2018-07-27 Genomic Health Inc Method to use gene expression to determine likelihood of clinical outcome of renal cancer
JP2013532482A (ja) * 2010-07-27 2013-08-19 ジェノミック ヘルス, インコーポレイテッド 遺伝子発現を用いた前立腺癌の予後を定量化する方法
EP2809812A4 (en) * 2012-01-31 2016-01-27 Genomic Health Inc GENE EXPRESSION PROFILE ALGORITHM AND PROSTATE CANCER PROGNOSTIC DETERMINATION TEST

Also Published As

Publication number Publication date
JP6351112B2 (ja) 2018-07-04
HK1201881A1 (en) 2015-09-11
US20140303002A1 (en) 2014-10-09
AU2020202164B2 (en) 2022-02-10
WO2013116144A1 (en) 2013-08-08
EP3739595A3 (en) 2021-01-27
MX2019007814A (es) 2019-09-05
US11011252B1 (en) 2021-05-18
US8725426B2 (en) 2014-05-13
EP3739595A2 (en) 2020-11-18
JP2015511814A (ja) 2015-04-23
SG11201404390WA (en) 2014-08-28
EP3179393A3 (en) 2017-09-13
AU2020202164A1 (en) 2020-04-16
NZ627887A (en) 2016-08-26
AU2013215448B2 (en) 2018-01-04
EP3179393A2 (en) 2017-06-14
MX351626B (es) 2017-10-23
EP3179393B1 (en) 2020-07-08
JP2017113008A (ja) 2017-06-29
IL233709A0 (en) 2014-09-30
IL262648A (en) 2018-12-31
JP6908571B2 (ja) 2021-07-28
JP2019013255A (ja) 2019-01-31
EP2809812A1 (en) 2014-12-10
SG10201605210PA (en) 2016-08-30
MX2014009283A (es) 2014-09-11
IL254255B (en) 2018-11-29
AU2013215448A1 (en) 2014-08-21
CA2863040C (en) 2022-04-19
ES2812105T3 (es) 2021-03-16
IL254255A0 (en) 2017-10-31
CO7051010A2 (es) 2014-09-10
AU2018201688B2 (en) 2020-02-27
AU2018201688A1 (en) 2018-04-05
NZ722902A (en) 2017-12-22
CA2863040A1 (en) 2013-08-08
EP2809812A4 (en) 2016-01-27
SG10201912312YA (en) 2020-02-27
US20130196321A1 (en) 2013-08-01
IL262648B (en) 2020-07-30
IL233709A (en) 2017-09-28
DK3179393T3 (da) 2020-07-27

Similar Documents

Publication Publication Date Title
MX2019007814A (es) Algoritmo de perfil de expresion genica y prueba para determinar la prognosis de cancer de prostata.
MX2018011725A (es) Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.
MX2020001156A (es) Metodo para el pronostico y tratamiento de metastasis de cancer.
MX2019013953A (es) Metodo basado en expresion genica para clasificar pacientes con cancer de riñon de acuerdo al riesgo de recurrencia.
MX2011011571A (es) Algoritmo de perfil de expresion genica y prueba para probabilidad de recidiva de cancer colorrectal y respuesta a la quimioterapia.
NZ705645A (en) Method to use gene expression to determine likelihood of clinical outcome of renal cancer
BR112014025269A2 (pt) método para o prognóstico e tratamento de metástase de câncer
MX368513B (es) Métodos in vitro para el pronóstico, diagnóstico y diseño de una terapia de metástasis de cáncer de pulmón.
HK1213946A1 (zh) 用於使用c-maf对前列腺癌转移进行诊断、预後和治疗的方法
WO2014144121A3 (en) Classification and actionability indices for lung cancer
EA201391074A1 (ru) Профили экспрессии генов рака толстой кишки и способы применения
EP2908132A3 (en) Prediction of drug sensitivity of lung tumors based on molecular and genetic signatures
EA201370063A1 (ru) Фосфолипидом рака
EP2619587A4 (en) BIOMARKER FOR PREDICTING THE REPRODUCTION OF A COLORECTAL CARCINOMA
BR112015022977A2 (pt) métodos para predição de risco de metástase em melanoma cutâneo
PH12015500388A1 (en) Cancer diagnostic and therapeutic method targeting molecules expressed in cancer stem cells
MX2013008252A (es) Firma de pronostico para la recurrencia de cancer colorrectal.
BR112017005421A2 (pt) método in vitro para prever se pacientes com câncer são propensos a reagir a um inibidor de receptor, kit e inibidor de egfr
BR112014023296A2 (pt) métodos para fazer tipagem de uma amostra de um paciente com hepatite b, para determinar se um paciente com hepatite b tem uma chance melhorada de um resultado positivo do tratamento da hepatite b, se um indivíduo tem uma predisposição genética para uma chance melhorada para um resultado positivo de tratamento da hepatite b, para identificar um gene, e para ensaiar quanto a presença de ácido nucleico, kit de partes ou arranjo ou microarranjo ou vetor, usos de pelo menos um polinucleotídeo isolado, de um kit de partes ou arranjo ou microarranjo ou vetor e de meios para determinar um nível de expressão de carnitina e/ou um derivado de carnitina
WO2015115923A3 (en) A profile of microrna in the blood as a test for the detection of lung cancer
WO2010093907A3 (en) An assay for the detection of recurrence in breast cancer using the novel tumor suppressor dear1
MX2013013153A (es) La expresion de kiaa1456 predice la supervivencia en pacientes con cancer de colon.
WO2013190468A3 (en) Computer-based predictor for prostate cancer
WO2014009055A9 (en) Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene.
WO2011133500A3 (en) Detection and analysis of epigenetic and genetic changes in tumor tissue