EA201400117A1 - Способы и нуклеиновые кислоты для определения прогноза у больных раком - Google Patents

Способы и нуклеиновые кислоты для определения прогноза у больных раком

Info

Publication number
EA201400117A1
EA201400117A1 EA201400117A EA201400117A EA201400117A1 EA 201400117 A1 EA201400117 A1 EA 201400117A1 EA 201400117 A EA201400117 A EA 201400117A EA 201400117 A EA201400117 A EA 201400117A EA 201400117 A1 EA201400117 A1 EA 201400117A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nucleic acids
cancer patients
prediction
determination
methods
Prior art date
Application number
EA201400117A
Other languages
English (en)
Other versions
EA034232B1 (ru
Inventor
Йёрн Левин
Мануэль Криспин
Original Assignee
Эпигеномикс Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эпигеномикс Аг filed Critical Эпигеномикс Аг
Publication of EA201400117A1 publication Critical patent/EA201400117A1/ru
Publication of EA034232B1 publication Critical patent/EA034232B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Данным изобретением предлагаются способы, нуклеиновые кислоты и наборы для определения прогноза у больных раком. Описываются геномные последовательности, профиль метилирования которых можно использовать для усовершенствованного выявления указанного расстройства, тем самым обеспечивая возможность усовершенствовать диагностику и лечение больных.
EA201400117A 2011-07-08 2012-07-09 Способы и нуклеиновые кислоты для определения прогноза у больных раком EA034232B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161505919P 2011-07-08 2011-07-08
PCT/EP2012/063436 WO2013007702A1 (en) 2011-07-08 2012-07-09 Methods and nucleic acids for determining the prognosis of a cancer subject

Publications (2)

Publication Number Publication Date
EA201400117A1 true EA201400117A1 (ru) 2014-06-30
EA034232B1 EA034232B1 (ru) 2020-01-20

Family

ID=46458553

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400117A EA034232B1 (ru) 2011-07-08 2012-07-09 Способы и нуклеиновые кислоты для определения прогноза у больных раком

Country Status (20)

Country Link
US (3) US10626462B2 (ru)
EP (1) EP2729579B1 (ru)
JP (1) JP6397762B2 (ru)
KR (1) KR102046668B1 (ru)
CN (2) CN108048573A (ru)
AU (1) AU2012282528B2 (ru)
BR (1) BR112014000443B1 (ru)
CA (1) CA2840149C (ru)
DK (1) DK2729579T3 (ru)
EA (1) EA034232B1 (ru)
ES (1) ES2654561T3 (ru)
HR (1) HRP20180001T1 (ru)
HU (1) HUE036036T2 (ru)
IL (1) IL230303B (ru)
LT (1) LT2729579T (ru)
MX (1) MX358117B (ru)
NO (1) NO2729579T3 (ru)
SI (1) SI2729579T1 (ru)
WO (1) WO2013007702A1 (ru)
ZA (1) ZA201400089B (ru)

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CN112195243A (zh) * 2020-09-22 2021-01-08 北京华大吉比爱生物技术有限公司 一种检测多基因甲基化的试剂盒及其应用
KR102404750B1 (ko) * 2021-10-14 2022-06-07 주식회사 엔도믹스 세포 유리 dna를 이용한 대장암 진단을 위한 메틸화 마커 유전자 및 이의 용도
CN114561452A (zh) * 2022-03-10 2022-05-31 天津市人民医院 mSEPT9作为预测结直肠癌患者术后复发风险标志物及用于评价化疗方案有效性的应用
KR102559496B1 (ko) * 2022-04-26 2023-07-25 연세대학교 산학협력단 핵산의 메틸화 여부 확인용 조성물 및 핵산의 메틸화 여부를 확인하는 방법
CN115029462B (zh) * 2022-08-10 2022-11-08 中国农业科学院农业质量标准与检测技术研究所 一种动植物疫病的核酸标准物质、形貌模拟方法及其应用
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Also Published As

Publication number Publication date
US20220243277A1 (en) 2022-08-04
CN103732759A (zh) 2014-04-16
LT2729579T (lt) 2018-02-26
HUE036036T2 (hu) 2018-06-28
MX2014000116A (es) 2014-03-27
BR112014000443A2 (pt) 2017-02-14
MX358117B (es) 2018-08-06
IL230303B (en) 2018-05-31
ES2654561T3 (es) 2018-02-14
CA2840149C (en) 2021-10-26
BR112014000443B1 (pt) 2021-03-23
US20150031021A1 (en) 2015-01-29
HRP20180001T1 (hr) 2018-03-09
EA034232B1 (ru) 2020-01-20
SI2729579T1 (en) 2018-07-31
JP2014520520A (ja) 2014-08-25
EP2729579A1 (en) 2014-05-14
KR102046668B1 (ko) 2019-11-19
NO2729579T3 (ru) 2018-03-03
WO2013007702A1 (en) 2013-01-17
EP2729579B1 (en) 2017-10-04
JP6397762B2 (ja) 2018-09-26
US11261499B2 (en) 2022-03-01
US20200308656A1 (en) 2020-10-01
DK2729579T3 (en) 2018-01-08
KR20140044385A (ko) 2014-04-14
CA2840149A1 (en) 2013-01-17
US10626462B2 (en) 2020-04-21
AU2012282528A1 (en) 2014-01-23
CN108048573A (zh) 2018-05-18
AU2012282528B2 (en) 2017-04-13
ZA201400089B (en) 2022-03-30

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