MX368513B - Métodos in vitro para el pronóstico, diagnóstico y diseño de una terapia de metástasis de cáncer de pulmón. - Google Patents
Métodos in vitro para el pronóstico, diagnóstico y diseño de una terapia de metástasis de cáncer de pulmón.Info
- Publication number
- MX368513B MX368513B MX2014014802A MX2014014802A MX368513B MX 368513 B MX368513 B MX 368513B MX 2014014802 A MX2014014802 A MX 2014014802A MX 2014014802 A MX2014014802 A MX 2014014802A MX 368513 B MX368513 B MX 368513B
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- MX
- Mexico
- Prior art keywords
- lung cancer
- diagnosis
- prognosis
- subject
- metastasis
- Prior art date
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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Abstract
La presente invención se refiere a un método in vitro para el diagnóstico de metástasis en un sujeto con cáncer de pulmón y/o para el pronóstico de la tendencia a desarrollar metástasis en un sujeto con cáncer de pulmón, caracterizado porque comprende: (i) cuantificar el número de copias de c-MAF en una muestra de tumor del sujeto, y (ii) comparar el número de copias previamente obtenido con el número de copias del gen en una muestra control, en donde, si el número de copias del gen se incrementa con respecto al número de copias del gen en la muestra control, entonces el sujeto tiene un diagnóstico positivo para metástasis o una tendencia mayor a desarrollar metástasis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261656372P | 2012-06-06 | 2012-06-06 | |
| PCT/IB2013/001859 WO2013182912A2 (en) | 2012-06-06 | 2013-06-06 | Method for the diagnosis, prognosis and treatment of lung cancer metastasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014014802A MX2014014802A (es) | 2015-05-11 |
| MX368513B true MX368513B (es) | 2019-10-07 |
Family
ID=49237517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014014802A MX368513B (es) | 2012-06-06 | 2013-06-06 | Métodos in vitro para el pronóstico, diagnóstico y diseño de una terapia de metástasis de cáncer de pulmón. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10006091B2 (es) |
| EP (2) | EP3467124A1 (es) |
| JP (1) | JP6386450B2 (es) |
| KR (1) | KR102226219B1 (es) |
| CN (1) | CN104603288B (es) |
| AU (2) | AU2013273242B2 (es) |
| BR (1) | BR112014030750A2 (es) |
| CA (1) | CA2875918A1 (es) |
| DK (1) | DK2859120T3 (es) |
| ES (1) | ES2705237T3 (es) |
| MX (1) | MX368513B (es) |
| TR (1) | TR201819859T4 (es) |
| WO (1) | WO2013182912A2 (es) |
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| EP3467124A1 (en) | 2012-06-06 | 2019-04-10 | Fundació Institut de Recerca Biomèdica IRB (Barcelona) | Method for the diagnosis, prognosis and treatment of lung cancer metastasis |
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| US20160040247A1 (en) | 2013-03-15 | 2016-02-11 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Method for the diagnosis, prognosis, and tratment of cancer metastasis |
| AU2014229505B2 (en) * | 2013-03-15 | 2020-02-27 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Method for the prognosis and treatment of cancer metastasis |
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| CN106055921A (zh) * | 2016-05-27 | 2016-10-26 | 华中农业大学 | 基于基因表达和药物靶标的药物活性预测与筛选方法 |
| CN106119405B (zh) * | 2016-08-31 | 2019-11-12 | 广州万德基因医学科技有限公司 | 一种肺癌的预后标记物、使用该标记预测肺癌预后的方法及应用 |
| CN107058480B (zh) * | 2016-12-14 | 2018-07-13 | 河北医科大学第四医院(河北省肿瘤医院) | 用于诊断肺腺癌的长链非编码rna标志物 |
| CN106815486B (zh) * | 2017-01-22 | 2021-06-04 | 华中农业大学 | 一种个性化用药的系统药理学方法 |
| CN107058499B (zh) * | 2017-01-25 | 2020-03-13 | 河北医科大学第四医院(河北省肿瘤医院) | 一种用于肺腺癌诊治的分子标志物 |
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| EP2859120A2 (en) | 2015-04-15 |
| JP6386450B2 (ja) | 2018-09-05 |
| JP2015521050A (ja) | 2015-07-27 |
| US11352673B2 (en) | 2022-06-07 |
| DK2859120T3 (en) | 2019-01-14 |
| ES2705237T3 (es) | 2019-03-22 |
| AU2013273242A1 (en) | 2014-12-18 |
| KR20150028965A (ko) | 2015-03-17 |
| CN104603288A (zh) | 2015-05-06 |
| WO2013182912A2 (en) | 2013-12-12 |
| CN104603288B (zh) | 2018-12-14 |
| HK1208501A1 (en) | 2016-03-04 |
| US20190119757A1 (en) | 2019-04-25 |
| KR102226219B1 (ko) | 2021-03-10 |
| WO2013182912A3 (en) | 2014-02-20 |
| WO2013182912A4 (en) | 2014-04-10 |
| BR112014030750A2 (pt) | 2017-08-22 |
| EP2859120B1 (en) | 2018-11-14 |
| AU2013273242B2 (en) | 2019-04-11 |
| EP3467124A1 (en) | 2019-04-10 |
| US10006091B2 (en) | 2018-06-26 |
| TR201819859T4 (tr) | 2019-01-21 |
| MX2014014802A (es) | 2015-05-11 |
| CA2875918A1 (en) | 2013-12-12 |
| US20150152506A1 (en) | 2015-06-04 |
| AU2019204269A1 (en) | 2019-07-04 |
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