BR112016029583A2 - ?kit ou dispositivo para a detecção de câncer esofágico e método de detecção? - Google Patents
?kit ou dispositivo para a detecção de câncer esofágico e método de detecção?Info
- Publication number
- BR112016029583A2 BR112016029583A2 BR112016029583A BR112016029583A BR112016029583A2 BR 112016029583 A2 BR112016029583 A2 BR 112016029583A2 BR 112016029583 A BR112016029583 A BR 112016029583A BR 112016029583 A BR112016029583 A BR 112016029583A BR 112016029583 A2 BR112016029583 A2 BR 112016029583A2
- Authority
- BR
- Brazil
- Prior art keywords
- esophageal cancer
- kit
- detection
- detection method
- detecting
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Abstract
a invenção pretende oferecer um kit ou um dispositivo para a detecção do câncer esofágico e um método para a detecção do câncer esofágico. a presente invenção provê um kit ou um dispositivo para a detecção do câncer esofágico, compreendendo ácido(s) nucleico(s) capaz(s) de ligar especificamente a mirna(s) em uma amostra de um sujeito, e um método para a detecção do câncer esofágico compreendendo a medição in vitro do(s) mirna(s).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014125036 | 2014-06-18 | ||
JP2015070379 | 2015-03-30 | ||
PCT/JP2015/067580 WO2015194627A1 (ja) | 2014-06-18 | 2015-06-18 | 食道がんの検出キット又はデバイス及び検出方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016029583A2 true BR112016029583A2 (pt) | 2017-10-24 |
Family
ID=54935605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016029583A BR112016029583A2 (pt) | 2014-06-18 | 2015-06-18 | ?kit ou dispositivo para a detecção de câncer esofágico e método de detecção? |
Country Status (10)
Country | Link |
---|---|
US (3) | US10619212B2 (pt) |
EP (2) | EP3816302A3 (pt) |
JP (4) | JP7090851B2 (pt) |
KR (3) | KR102523245B1 (pt) |
CN (2) | CN106459964B (pt) |
BR (1) | BR112016029583A2 (pt) |
CA (2) | CA2951390C (pt) |
DK (1) | DK3159406T3 (pt) |
RU (1) | RU2017101353A (pt) |
WO (1) | WO2015194627A1 (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2016152143A (ru) | 2014-05-30 | 2018-07-04 | Торэй Индастриз, Инк. | Набор или устройство для обнаружения рака поджелудочной железы и способ обнаружения |
WO2017131208A1 (ja) * | 2016-01-28 | 2017-08-03 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
KR20230129606A (ko) * | 2016-03-31 | 2023-09-08 | 도레이 카부시키가이샤 | 조기 췌장암 또는 췌장암 전구 병변의 검출 키트 또는 디바이스 및 검출 방법 |
CN106244686B (zh) * | 2016-07-31 | 2019-07-12 | 成都望路医药技术有限公司 | mir-3620的新用途 |
CN106119392B (zh) * | 2016-08-25 | 2019-12-31 | 朱伟 | 一种与食管鳞癌辅助诊断相关的血清miRNA标志物及其应用 |
CN106834470A (zh) * | 2017-02-17 | 2017-06-13 | 张灏 | miRNA在制备癌症诊断试剂盒中的用途 |
CN106947738B (zh) * | 2017-02-17 | 2020-04-10 | 中山大学 | microRNA-4281的新用途 |
CA3068585A1 (en) * | 2017-06-29 | 2019-01-03 | Toray Industries, Inc. | Kit, device, and method for detecting lung cancer |
CN107190077A (zh) * | 2017-06-30 | 2017-09-22 | 上海中医药大学 | 尿液miRNAs生物标志物及其筛选方法和应用 |
CN107475388B (zh) * | 2017-08-22 | 2020-05-19 | 深圳市恩普电子技术有限公司 | 鼻咽癌相关的miRNA作为生物标志物的应用及鼻咽癌检测试剂盒 |
CN107400732A (zh) * | 2017-09-26 | 2017-11-28 | 苏州立豪生物科技有限公司 | 一种用于检测胃癌的试剂盒 |
TWI688655B (zh) * | 2017-11-06 | 2020-03-21 | 高雄醫學大學 | 甘胺酸n-甲基轉移酶剔除小鼠應用高通量定序法建立新穎微小核醣核酸癌症與肝臟疾病標誌物與套組 |
CN108103196A (zh) * | 2018-02-05 | 2018-06-01 | 上海易毕恩生物技术有限公司 | 一种用于检测食管癌的基因标志物及其用途和检测方法 |
JP7462227B2 (ja) * | 2018-04-25 | 2024-04-05 | 東レ株式会社 | 膀胱がんの検出のためのキット、デバイス及び方法 |
US20210269884A1 (en) | 2018-06-21 | 2021-09-02 | Public University Corporation Nagoya City University | Gastric cancer biomarker and use thereof |
CA3108241A1 (en) * | 2018-07-31 | 2020-02-06 | Toray Industries, Inc. | Method for evaluating quality of body fluid specimen |
WO2020032228A1 (ja) * | 2018-08-10 | 2020-02-13 | 東レ株式会社 | 前立腺がんの検出のためのキット、デバイス及び方法 |
CN109270267B (zh) * | 2018-11-02 | 2019-04-02 | 上海宝藤生物医药科技股份有限公司 | 用于胰腺癌早期诊断的外泌体cd82蛋白及其检测试剂盒 |
JPWO2021019944A1 (pt) * | 2019-07-29 | 2021-02-04 | ||
WO2021132232A1 (ja) * | 2019-12-26 | 2021-07-01 | 東レ株式会社 | 血清検体の品質評価方法 |
WO2021132231A1 (ja) * | 2019-12-26 | 2021-07-01 | 東レ株式会社 | 血清検体の品質評価方法 |
IT202000030833A1 (it) * | 2020-12-15 | 2022-06-15 | St Fisioterapici Ospitalieri Ifo | Metodo per la diagnosi in vitro di mucosite in pazienti oncologici sottoposti a terapia anti-tumorale. |
CN112641797B (zh) * | 2020-12-30 | 2021-12-17 | 温州医科大学 | 抑制结直肠癌生长、转移的靶标与诊断标志物及其应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3124614A (en) | 1964-03-10 | Preparation of z-substituteb | ||
DE69233472T2 (de) * | 1991-04-05 | 2006-02-09 | The General Hospital Corp., Charlestown | Parathormonrezeptor und dafür codierende DNA |
GB0412301D0 (en) * | 2004-06-02 | 2004-07-07 | Diagenic As | Product and method |
CN102399870B (zh) * | 2006-11-28 | 2014-04-16 | 博奥生物有限公司 | 一种确定食道癌病人生存预后的试剂 |
CN101316935B (zh) | 2006-11-28 | 2012-02-29 | 博奥生物有限公司 | 一种用于诊断食道癌的芯片 |
US20100285471A1 (en) | 2007-10-11 | 2010-11-11 | The Ohio State University Research Foundation | Methods and Compositions for the Diagnosis and Treatment of Esphageal Adenocarcinomas |
US8071562B2 (en) * | 2007-12-01 | 2011-12-06 | Mirna Therapeutics, Inc. | MiR-124 regulated genes and pathways as targets for therapeutic intervention |
CN101851682B (zh) * | 2010-06-25 | 2013-08-28 | 中国人民解放军南京军区南京总医院 | 一种用于检测食管鳞状细胞癌的微小核糖核酸组合及其应用 |
US20140031246A1 (en) * | 2010-07-22 | 2014-01-30 | The Johns Hopkins University | Circulating micrornas are biomarkers of various diseases |
EP2699666B1 (en) * | 2011-04-18 | 2016-10-05 | DiamiR, LLC | miRNA-BASED UNIVERSAL SCREENING TEST (UST) |
JP2014125036A (ja) | 2012-12-25 | 2014-07-07 | Showa Corp | 電動パワーステアリング装置 |
JP2015070379A (ja) | 2013-09-27 | 2015-04-13 | 日本電気株式会社 | 検波回路および検波方法 |
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2015
- 2015-06-18 EP EP20207038.9A patent/EP3816302A3/en active Pending
- 2015-06-18 US US15/317,857 patent/US10619212B2/en active Active
- 2015-06-18 DK DK15809775.8T patent/DK3159406T3/da active
- 2015-06-18 BR BR112016029583A patent/BR112016029583A2/pt not_active Application Discontinuation
- 2015-06-18 WO PCT/JP2015/067580 patent/WO2015194627A1/ja active Application Filing
- 2015-06-18 RU RU2017101353A patent/RU2017101353A/ru not_active Application Discontinuation
- 2015-06-18 CA CA2951390A patent/CA2951390C/en active Active
- 2015-06-18 KR KR1020177000803A patent/KR102523245B1/ko active IP Right Grant
- 2015-06-18 CN CN201580031909.6A patent/CN106459964B/zh active Active
- 2015-06-18 JP JP2016529504A patent/JP7090851B2/ja active Active
- 2015-06-18 KR KR1020237012596A patent/KR102581671B1/ko active IP Right Grant
- 2015-06-18 KR KR1020237031837A patent/KR20230141885A/ko not_active Application Discontinuation
- 2015-06-18 EP EP15809775.8A patent/EP3159406B1/en active Active
- 2015-06-18 CA CA3224457A patent/CA3224457A1/en active Pending
- 2015-06-18 CN CN202010760220.XA patent/CN111910002B/zh active Active
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2020
- 2020-02-27 US US16/803,390 patent/US11542558B2/en active Active
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2021
- 2021-03-08 JP JP2021035949A patent/JP7153283B2/ja active Active
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2022
- 2022-09-21 JP JP2022150123A patent/JP7436995B2/ja active Active
- 2022-11-18 US US17/990,164 patent/US20230118787A1/en active Pending
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2024
- 2024-02-01 JP JP2024013950A patent/JP2024042061A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230118787A1 (en) | 2023-04-20 |
KR102581671B1 (ko) | 2023-09-22 |
US20170130273A1 (en) | 2017-05-11 |
JP7090851B2 (ja) | 2022-06-27 |
JP2021100411A (ja) | 2021-07-08 |
JP2022174295A (ja) | 2022-11-22 |
US20200318199A1 (en) | 2020-10-08 |
EP3816302A2 (en) | 2021-05-05 |
KR20230053004A (ko) | 2023-04-20 |
KR20230141885A (ko) | 2023-10-10 |
EP3816302A3 (en) | 2021-07-07 |
KR102523245B1 (ko) | 2023-04-20 |
RU2017101353A (ru) | 2018-07-18 |
CN106459964A (zh) | 2017-02-22 |
JP7436995B2 (ja) | 2024-02-22 |
JP2024042061A (ja) | 2024-03-27 |
WO2015194627A1 (ja) | 2015-12-23 |
CA3224457A1 (en) | 2015-12-23 |
JPWO2015194627A1 (ja) | 2017-04-20 |
CN106459964B (zh) | 2020-08-21 |
US10619212B2 (en) | 2020-04-14 |
JP7153283B2 (ja) | 2022-10-14 |
DK3159406T3 (da) | 2021-01-11 |
CA2951390A1 (en) | 2015-12-23 |
EP3159406B1 (en) | 2020-12-09 |
EP3159406A1 (en) | 2017-04-26 |
KR20170018406A (ko) | 2017-02-17 |
CA2951390C (en) | 2024-02-13 |
US11542558B2 (en) | 2023-01-03 |
CN111910002A (zh) | 2020-11-10 |
EP3159406A4 (en) | 2018-04-18 |
CN111910002B (zh) | 2024-04-12 |
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