WO2014009055A9 - Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene. - Google Patents

Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene. Download PDF

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Publication number
WO2014009055A9
WO2014009055A9 PCT/EP2013/061286 EP2013061286W WO2014009055A9 WO 2014009055 A9 WO2014009055 A9 WO 2014009055A9 EP 2013061286 W EP2013061286 W EP 2013061286W WO 2014009055 A9 WO2014009055 A9 WO 2014009055A9
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WO
WIPO (PCT)
Prior art keywords
response
tmem45a
predicting
gene
monitoring
Prior art date
Application number
PCT/EP2013/061286
Other languages
French (fr)
Other versions
WO2014009055A1 (en
Inventor
Carine Michiels
Lionel FLAMANT
Original Assignee
Universite De Namur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Universite De Namur filed Critical Universite De Namur
Priority to EP13727840.4A priority Critical patent/EP2872645A1/en
Publication of WO2014009055A1 publication Critical patent/WO2014009055A1/en
Publication of WO2014009055A9 publication Critical patent/WO2014009055A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A method for prognosticating the outcome of a cancer, for predicting the response to a chemotherapy treatment of a cancer or for monitoring the response to a chemotherapy treatment of a cancer, comprising the step of measuring the expression level of TMEM45A gene in a sample
PCT/EP2013/061286 2012-07-12 2013-05-31 Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene. WO2014009055A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP13727840.4A EP2872645A1 (en) 2012-07-12 2013-05-31 Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12176145 2012-07-12
EP12176145.6 2012-07-12
EPPCT/EP2013/053588 2013-02-22
EP2013053588 2013-02-22

Publications (2)

Publication Number Publication Date
WO2014009055A1 WO2014009055A1 (en) 2014-01-16
WO2014009055A9 true WO2014009055A9 (en) 2014-02-27

Family

ID=48579034

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2013/061286 WO2014009055A1 (en) 2012-07-12 2013-05-31 Method and kit for predicting or monitoring the response of a cancer patient to chemotherapy, based on measuring the expression level of tmem45a gene.

Country Status (2)

Country Link
EP (1) EP2872645A1 (en)
WO (1) WO2014009055A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113293208B (en) * 2020-02-21 2022-05-03 中国农业大学 Molecular marker related to lung cancer proliferation and metastasis and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090239223A1 (en) * 2006-07-13 2009-09-24 Siemens Healthcare Diagnostics Inc. Prediction of Breast Cancer Response to Taxane-Based Chemotherapy
AT504702A1 (en) * 2006-12-22 2008-07-15 Arc Austrian Res Centers Gmbh SET OF TUMOR MARKERS
EP2531619A4 (en) * 2010-02-05 2013-08-21 Myriad Genetics Inc Hypoxia-related gene signatures for cancer classification
WO2012022634A1 (en) * 2010-08-16 2012-02-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Classification, diagnosis and prognosis of multiple myeloma

Also Published As

Publication number Publication date
WO2014009055A1 (en) 2014-01-16
EP2872645A1 (en) 2015-05-20

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