MX337650B - Metodos para predecir el desenlace clinico del cancer. - Google Patents

Metodos para predecir el desenlace clinico del cancer.

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Publication number
MX337650B
MX337650B MX2012005822A MX2012005822A MX337650B MX 337650 B MX337650 B MX 337650B MX 2012005822 A MX2012005822 A MX 2012005822A MX 2012005822 A MX2012005822 A MX 2012005822A MX 337650 B MX337650 B MX 337650B
Authority
MX
Mexico
Prior art keywords
cancer
methods
genes
clinical outcome
prognosis
Prior art date
Application number
MX2012005822A
Other languages
English (en)
Other versions
MX2012005822A (es
Inventor
Joffre B Baker
Maureen T Cronin
Francois Collin
mei-lan Liu
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of MX2012005822A publication Critical patent/MX2012005822A/es
Publication of MX337650B publication Critical patent/MX337650B/es

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a métodos para determinar el pronóstico y el tratamiento adecuado para pacientes con diagnóstico de cáncer, basándose en los niveles de expresión de uno más biomarcadores. De manera más particular, la invención se refiere a la identificación de genes, o de conjuntos de genes, capaces de distinguir a los pacientes de cáncer de mama con buen pronóstico clínico respecto de aquellos que tienen un mal pronóstico clínico. La invención también proporciona métodos para obtener un informe genómico personalizado para un paciente de cáncer. La invención también se refiera a sistemas de computadora y software para análisis de datos utilizando los métodos de pronóstico y estadística divulgados en la presente.
MX2012005822A 2009-11-23 2010-11-19 Metodos para predecir el desenlace clinico del cancer. MX337650B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376309P 2009-11-23 2009-11-23
PCT/US2010/057490 WO2011063274A2 (en) 2009-11-23 2010-11-19 Methods to predict clinical outcome of cancer

Publications (2)

Publication Number Publication Date
MX2012005822A MX2012005822A (es) 2012-06-19
MX337650B true MX337650B (es) 2016-03-14

Family

ID=44060376

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2012005822A MX337650B (es) 2009-11-23 2010-11-19 Metodos para predecir el desenlace clinico del cancer.
MX2016003089A MX363817B (es) 2009-11-23 2010-11-19 Métodos para predecir el desenlace clínico del cáncer.
MX2019003811A MX2019003811A (es) 2009-11-23 2012-05-18 Metodos para predecir el desenlace clinico del cancer.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2016003089A MX363817B (es) 2009-11-23 2010-11-19 Métodos para predecir el desenlace clínico del cáncer.
MX2019003811A MX2019003811A (es) 2009-11-23 2012-05-18 Metodos para predecir el desenlace clinico del cancer.

Country Status (13)

Country Link
US (4) US20110123990A1 (es)
EP (4) EP4350001A3 (es)
JP (7) JP5964752B2 (es)
AU (1) AU2010321829B2 (es)
CA (2) CA3043089A1 (es)
DK (1) DK2504451T3 (es)
ES (1) ES2735993T3 (es)
HU (1) HUE044374T2 (es)
IL (5) IL219051A (es)
MX (3) MX337650B (es)
NZ (1) NZ599194A (es)
PL (1) PL2504451T3 (es)
WO (1) WO2011063274A2 (es)

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Also Published As

Publication number Publication date
AU2010321829B2 (en) 2015-07-30
MX2012005822A (es) 2012-06-19
EP2504451B1 (en) 2019-06-05
US20170211154A1 (en) 2017-07-27
DK2504451T3 (da) 2019-08-05
NZ599194A (en) 2014-07-25
JP2022169647A (ja) 2022-11-09
EP2504451A4 (en) 2016-07-06
IL276487B (en) 2022-03-01
CA3043089A1 (en) 2011-05-26
CA2776751A1 (en) 2011-05-26
EP3556867A1 (en) 2019-10-23
JP2022166064A (ja) 2022-11-01
MX363817B (es) 2019-04-04
EP3739060A1 (en) 2020-11-18
US20110123990A1 (en) 2011-05-26
US20210062275A1 (en) 2021-03-04
WO2011063274A2 (en) 2011-05-26
AU2010321829A1 (en) 2012-05-03
JP2021058207A (ja) 2021-04-15
CA2776751C (en) 2019-07-02
IL219051A (en) 2016-12-29
IL264072A (en) 2019-02-28
EP4350001A2 (en) 2024-04-10
IL264072B (en) 2020-08-31
WO2011063274A3 (en) 2014-03-27
IL276487A (en) 2020-09-30
JP2018196385A (ja) 2018-12-13
HUE044374T2 (hu) 2019-10-28
IL257063B (en) 2019-01-31
EP4350001A3 (en) 2024-06-19
JP7042717B2 (ja) 2022-03-28
MX2019003811A (es) 2019-08-05
JP2013514058A (ja) 2013-04-25
JP2024037948A (ja) 2024-03-19
IL249159A0 (en) 2017-01-31
IL219051A0 (en) 2012-06-28
PL2504451T3 (pl) 2019-09-30
JP5964752B2 (ja) 2016-08-03
JP2016214245A (ja) 2016-12-22
US20190241967A1 (en) 2019-08-08
EP2504451A2 (en) 2012-10-03
ES2735993T3 (es) 2019-12-23

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