MX337650B - Metodos para predecir el desenlace clinico del cancer. - Google Patents
Metodos para predecir el desenlace clinico del cancer.Info
- Publication number
- MX337650B MX337650B MX2012005822A MX2012005822A MX337650B MX 337650 B MX337650 B MX 337650B MX 2012005822 A MX2012005822 A MX 2012005822A MX 2012005822 A MX2012005822 A MX 2012005822A MX 337650 B MX337650 B MX 337650B
- Authority
- MX
- Mexico
- Prior art keywords
- cancer
- methods
- genes
- clinical outcome
- prognosis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Theoretical Computer Science (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a métodos para determinar el pronóstico y el tratamiento adecuado para pacientes con diagnóstico de cáncer, basándose en los niveles de expresión de uno más biomarcadores. De manera más particular, la invención se refiere a la identificación de genes, o de conjuntos de genes, capaces de distinguir a los pacientes de cáncer de mama con buen pronóstico clínico respecto de aquellos que tienen un mal pronóstico clínico. La invención también proporciona métodos para obtener un informe genómico personalizado para un paciente de cáncer. La invención también se refiera a sistemas de computadora y software para análisis de datos utilizando los métodos de pronóstico y estadística divulgados en la presente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26376309P | 2009-11-23 | 2009-11-23 | |
PCT/US2010/057490 WO2011063274A2 (en) | 2009-11-23 | 2010-11-19 | Methods to predict clinical outcome of cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2012005822A MX2012005822A (es) | 2012-06-19 |
MX337650B true MX337650B (es) | 2016-03-14 |
Family
ID=44060376
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012005822A MX337650B (es) | 2009-11-23 | 2010-11-19 | Metodos para predecir el desenlace clinico del cancer. |
MX2016003089A MX363817B (es) | 2009-11-23 | 2010-11-19 | Métodos para predecir el desenlace clínico del cáncer. |
MX2019003811A MX2019003811A (es) | 2009-11-23 | 2012-05-18 | Metodos para predecir el desenlace clinico del cancer. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016003089A MX363817B (es) | 2009-11-23 | 2010-11-19 | Métodos para predecir el desenlace clínico del cáncer. |
MX2019003811A MX2019003811A (es) | 2009-11-23 | 2012-05-18 | Metodos para predecir el desenlace clinico del cancer. |
Country Status (13)
Country | Link |
---|---|
US (4) | US20110123990A1 (es) |
EP (4) | EP4350001A3 (es) |
JP (7) | JP5964752B2 (es) |
AU (1) | AU2010321829B2 (es) |
CA (2) | CA3043089A1 (es) |
DK (1) | DK2504451T3 (es) |
ES (1) | ES2735993T3 (es) |
HU (1) | HUE044374T2 (es) |
IL (5) | IL219051A (es) |
MX (3) | MX337650B (es) |
NZ (1) | NZ599194A (es) |
PL (1) | PL2504451T3 (es) |
WO (1) | WO2011063274A2 (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
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US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
EP2163650B1 (en) | 2004-04-09 | 2015-08-05 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
ES2778851T3 (es) * | 2004-11-05 | 2020-08-12 | Genomic Health Inc | Predicción de la respuesta a la quimioterapia mediante el uso de marcadores de expresión génica |
WO2007123772A2 (en) | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
CN102132160A (zh) * | 2008-06-26 | 2011-07-20 | 达纳-法伯癌症研究院有限公司 | 与转移有关的信号和决定子以及它们的使用方法及用途 |
US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
HUE044374T2 (hu) * | 2009-11-23 | 2019-10-28 | Genomic Health Inc | Módszerek rák klinikai kimenetelének elõrejelzésére |
US9551034B2 (en) | 2010-01-11 | 2017-01-24 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
GB201009798D0 (en) | 2010-06-11 | 2010-07-21 | Immunovia Ab | Method,array and use thereof |
EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
JP2013532482A (ja) | 2010-07-27 | 2013-08-19 | ジェノミック ヘルス, インコーポレイテッド | 遺伝子発現を用いた前立腺癌の予後を定量化する方法 |
US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
JP2014509868A (ja) * | 2011-03-26 | 2014-04-24 | オレゴン ヘルス アンド サイエンス ユニバーシティー | 癌の予後のための遺伝子発現予測因子 |
AU2012203810B2 (en) * | 2011-06-22 | 2013-12-05 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
WO2013006495A2 (en) * | 2011-07-01 | 2013-01-10 | Dana-Farber Cancer Institute, Inc. | Methods of predicting prognosis in cancer |
AU2012281152B2 (en) * | 2011-07-13 | 2017-09-07 | The Multiple Myeloma Research Foundation, Inc. | Methods for data collection and distribution |
AU2012296405B2 (en) * | 2011-08-16 | 2016-03-17 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of breast cancer |
JP6147755B2 (ja) * | 2011-11-08 | 2017-06-14 | ジェノミック ヘルス, インコーポレイテッド | 乳癌の予後を予測する方法 |
JP5805518B2 (ja) * | 2011-12-21 | 2015-11-04 | 株式会社島津製作所 | マルチプレックス大腸がんマーカーパネル |
NZ722902A (en) | 2012-01-31 | 2017-12-22 | Genomic Health Inc | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
EP2839034A4 (en) * | 2012-04-20 | 2016-01-06 | Sloan Kettering Inst Cancer | GENE EXPRESSION PROFILES ASSOCIATED WITH METASTASIC BREAST CANCER |
US20150299799A1 (en) * | 2012-10-05 | 2015-10-22 | Michael Sturzl | Method for Detecting an Increased Risk or Incidence of Colorectal Cancer |
EP2920322B1 (en) | 2012-11-16 | 2023-01-11 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
KR101672531B1 (ko) * | 2013-04-18 | 2016-11-17 | 주식회사 젠큐릭스 | 조기 유방암 예후 예측 진단용 유전자 마커 및 이의 용도 |
SG11201506987VA (en) * | 2013-05-30 | 2015-10-29 | Genomic Health Inc | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
WO2014195032A1 (en) * | 2013-06-07 | 2014-12-11 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
US20170073763A1 (en) * | 2014-03-12 | 2017-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and Compositions for Assessing Patients with Non-small Cell Lung Cancer |
WO2015175692A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
WO2016046640A2 (en) | 2014-09-26 | 2016-03-31 | Medical Prognosis Institute A/S | Methods for predicting drug responsiveness |
WO2016092299A1 (en) * | 2014-12-09 | 2016-06-16 | Medical Research Council | Methods and kits for predicting the response to therapy of cancer |
US10704081B2 (en) | 2015-10-30 | 2020-07-07 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay |
EP3389481A4 (en) | 2015-12-18 | 2019-05-22 | Clear Gene, Inc. | PROCESSES, COMPOSITIONS, KITS AND DEVICES FOR FAST LANALYSIS OF BIOLOGICAL MARKERS |
WO2018048354A1 (en) * | 2016-09-07 | 2018-03-15 | Agency For Science, Technology And Research | A method of identifying risk of cancer and therapeutic options |
US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
WO2018212192A1 (ja) * | 2017-05-18 | 2018-11-22 | 京都府公立大学法人 | 癌の予後及び/又は転移可能性を評価する方法及びマーカー |
EP3513280A4 (en) | 2017-11-13 | 2020-07-22 | The Multiple Myeloma Research Foundation, Inc. | INTEGRATED, MOLECULAR, OMIC, IMMUNOTHERAPY, METABOLIC, EPIGENETIC AND CLINICAL DATABASE |
WO2019173644A1 (en) * | 2018-03-08 | 2019-09-12 | University Of Notre Dame Du Lac | Systems and methods for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and administering treatment protocols based thereon |
JP7199045B2 (ja) * | 2018-04-13 | 2023-01-05 | 国立大学法人大阪大学 | 乳癌の予後に関する情報の取得方法、乳癌の予後の判定装置及びコンピュータプログラム |
JP7444376B2 (ja) | 2018-09-21 | 2024-03-06 | 国立大学法人 東京大学 | がんの予後判定方法 |
JP2019032334A (ja) * | 2018-10-03 | 2019-02-28 | イムノヴィア・アクチエボラーグ | 乳癌関連の疾患状態を決定する方法およびこの方法における使用のためのアレイ |
KR102216645B1 (ko) * | 2018-10-29 | 2021-02-17 | 사회복지법인 삼성생명공익재단 | 폐암의 분자 아형 결정을 위한 바이오마커 패널 및 이의 용도 |
JP2022512152A (ja) * | 2018-12-08 | 2022-02-02 | ピーエフエス・ジェノミクス・インコーポレイテッド | 乳がんの予後についてのトランスクリプトームプロファイリング |
CN111235270B (zh) * | 2019-08-29 | 2022-04-29 | 北京臻知医学科技有限责任公司 | 一种基于高通量测序法的肿瘤抗原表达检测引物及试剂盒 |
US20210358573A1 (en) * | 2020-01-23 | 2021-11-18 | The Broad Institute, Inc. | Molecular spatial mapping of metastatic tumor microenvironment |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1410011B1 (en) * | 2001-06-18 | 2011-03-23 | Rosetta Inpharmatics LLC | Diagnosis and prognosis of breast cancer patients |
US7171311B2 (en) * | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
US7705120B2 (en) * | 2001-06-21 | 2010-04-27 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
EP2261368A1 (en) * | 2002-03-13 | 2010-12-15 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
US20040067234A1 (en) * | 2002-07-11 | 2004-04-08 | Paz Einat | Isocitrate dehydrogenase and uses thereof |
US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
JP4906505B2 (ja) * | 2003-07-10 | 2012-03-28 | ジェノミック ヘルス, インコーポレイテッド | 癌診断のための発現プロフィールアルゴリズムおよび試験 |
WO2005086891A2 (en) * | 2004-03-05 | 2005-09-22 | Rosetta Inpharmatics Llc | Classification of breast cancer patients using a combination of clinical criteria and informative genesets |
US20080299550A1 (en) * | 2004-09-20 | 2008-12-04 | Bayer Healthcare Ag | Methods and Kits For the Prediction of Therapeutic Success and Recurrence Free Survival In Cancer Therapy |
CA2612021A1 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
TWI304443B (en) * | 2005-12-30 | 2008-12-21 | Nat Health Research Institutes | Alpha-enolase specific antibody and method of use |
WO2007123772A2 (en) * | 2006-03-31 | 2007-11-01 | Genomic Health, Inc. | Genes involved in estrogen metabolism |
JP2010524456A (ja) * | 2007-04-16 | 2010-07-22 | イプソゲン | 乳癌に罹患している雌哺乳動物に対する臨床転帰の傾向を評価する方法 |
WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
WO2009095319A1 (en) * | 2008-01-28 | 2009-08-06 | Siemens Healthcare Diagnostics Gmbh | Cancer prognosis by majority voting |
WO2009132928A2 (en) * | 2008-05-02 | 2009-11-05 | Siemens Healthcare Diagnostics Gmbh | Molecular markers for cancer prognosis |
HUE044374T2 (hu) * | 2009-11-23 | 2019-10-28 | Genomic Health Inc | Módszerek rák klinikai kimenetelének elõrejelzésére |
-
2010
- 2010-11-19 HU HUE10832289 patent/HUE044374T2/hu unknown
- 2010-11-19 US US12/950,732 patent/US20110123990A1/en not_active Abandoned
- 2010-11-19 EP EP23213439.5A patent/EP4350001A3/en active Pending
- 2010-11-19 JP JP2012540103A patent/JP5964752B2/ja active Active
- 2010-11-19 WO PCT/US2010/057490 patent/WO2011063274A2/en active Application Filing
- 2010-11-19 EP EP20177718.2A patent/EP3739060A1/en not_active Withdrawn
- 2010-11-19 AU AU2010321829A patent/AU2010321829B2/en active Active
- 2010-11-19 CA CA3043089A patent/CA3043089A1/en not_active Withdrawn
- 2010-11-19 MX MX2012005822A patent/MX337650B/es active IP Right Grant
- 2010-11-19 EP EP10832289.2A patent/EP2504451B1/en active Active
- 2010-11-19 DK DK10832289.2T patent/DK2504451T3/da active
- 2010-11-19 PL PL10832289T patent/PL2504451T3/pl unknown
- 2010-11-19 EP EP19175741.8A patent/EP3556867A1/en not_active Withdrawn
- 2010-11-19 NZ NZ599194A patent/NZ599194A/en unknown
- 2010-11-19 MX MX2016003089A patent/MX363817B/es unknown
- 2010-11-19 CA CA2776751A patent/CA2776751C/en active Active
- 2010-11-19 ES ES10832289T patent/ES2735993T3/es active Active
-
2012
- 2012-04-04 IL IL219051A patent/IL219051A/en active IP Right Grant
- 2012-05-18 MX MX2019003811A patent/MX2019003811A/es unknown
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2016
- 2016-06-30 JP JP2016129697A patent/JP2016214245A/ja active Pending
- 2016-11-23 IL IL249159A patent/IL249159A0/en unknown
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2017
- 2017-02-03 US US15/423,977 patent/US20170211154A1/en not_active Abandoned
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2018
- 2018-01-21 IL IL257063A patent/IL257063B/en active IP Right Grant
- 2018-08-02 JP JP2018145578A patent/JP7042717B2/ja active Active
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2019
- 2019-01-03 IL IL264072A patent/IL264072B/en active IP Right Grant
- 2019-01-09 US US16/243,207 patent/US20190241967A1/en not_active Abandoned
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2020
- 2020-08-04 IL IL276487A patent/IL276487B/en unknown
- 2020-09-11 US US17/018,143 patent/US20210062275A1/en active Pending
- 2020-12-28 JP JP2020218527A patent/JP2021058207A/ja active Pending
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2022
- 2022-08-02 JP JP2022123265A patent/JP2022166064A/ja active Pending
- 2022-08-16 JP JP2022129605A patent/JP2022169647A/ja active Pending
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2023
- 2023-12-18 JP JP2023213416A patent/JP2024037948A/ja active Pending
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