MX369628B - Genes nano46 y metodos para predecir el resultado del cancer de mama. - Google Patents
Genes nano46 y metodos para predecir el resultado del cancer de mama.Info
- Publication number
- MX369628B MX369628B MX2014014275A MX2014014275A MX369628B MX 369628 B MX369628 B MX 369628B MX 2014014275 A MX2014014275 A MX 2014014275A MX 2014014275 A MX2014014275 A MX 2014014275A MX 369628 B MX369628 B MX 369628B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- breast cancer
- subject
- gene expression
- evaluating
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un método para determinar el riesgo de recidiva de cáncer de mama en un sujeto caracterizado porque comprende: determinar el tamaño de un tumor de cáncer de mama del sujeto: determinar un valor de correlación del tumor de cáncer de mama del sujeto para cada uno de por lo menos cuatro subtipos intrínsecos que incluyen tipo Basal, Luminal A, Luminal B, o enriquecido con HER-2, al medir la expresión de por lo menos cuarenta de los genes en la lista de genes intrínsecos en el tumor de cáncer de mama del sujeto.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261650209P | 2012-05-22 | 2012-05-22 | |
US201361753673P | 2013-01-17 | 2013-01-17 | |
PCT/US2013/042157 WO2013177245A2 (en) | 2012-05-22 | 2013-05-22 | Nano46 genes and methods to predict breast cancer outcome |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014014275A MX2014014275A (es) | 2015-07-06 |
MX369628B true MX369628B (es) | 2019-11-14 |
Family
ID=49624503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014014275A MX369628B (es) | 2012-05-22 | 2013-05-22 | Genes nano46 y metodos para predecir el resultado del cancer de mama. |
Country Status (12)
Country | Link |
---|---|
US (3) | US20130337444A1 (es) |
EP (1) | EP2852689B1 (es) |
JP (1) | JP6325530B2 (es) |
CN (2) | CN104704128A (es) |
AU (1) | AU2013266419B2 (es) |
BR (1) | BR112014029300A2 (es) |
CA (1) | CA2874492C (es) |
ES (1) | ES2763931T3 (es) |
IL (1) | IL235795B (es) |
IN (1) | IN2014MN02418A (es) |
MX (1) | MX369628B (es) |
WO (1) | WO2013177245A2 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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ES2457534T3 (es) | 2008-05-30 | 2014-04-28 | The University Of North Carolina At Chapel Hill | Perfiles de expresión génica para predecir desenlaces en cáncer de mama |
AU2012229123B2 (en) | 2011-03-15 | 2017-02-02 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with anthracycline therapy |
GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
EP2785873A4 (en) | 2011-11-30 | 2015-11-11 | Univ North Carolina | METHOD FOR THE TREATMENT OF BREAST CANCER WITH TAXAN THERAPY |
EP2909337B1 (en) | 2012-10-17 | 2019-01-09 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
EP2997163A4 (en) * | 2013-05-13 | 2017-02-22 | Nanostring Technologies, Inc | Methods to predict risk of recurrence in node-positive early breast cancer |
LT3013983T (lt) | 2013-06-25 | 2023-05-10 | Prognosys Biosciences, Inc. | Erdviniai koduoti biologiniai tyrimai, naudojant mikrofluidinį įrenginį |
US20150072021A1 (en) | 2013-09-09 | 2015-03-12 | British Columbia Cancer Agency Branch | Methods and Kits for Predicting Outcome and Methods and Kits for Treating Breast Cancer with Radiation Therapy |
KR102105236B1 (ko) | 2014-11-21 | 2020-04-28 | 나노스트링 테크놀로지스, 인크. | 무효소 및 무증폭 시퀀싱 |
CA2968519C (en) * | 2014-11-24 | 2024-01-09 | Nanostring Technologies, Inc. | Methods and apparatuses for gene purification and imaging |
AU2015359479A1 (en) * | 2014-12-09 | 2017-06-15 | King's College London | Breast cancer treatment with taxane therapy |
EP4321627A3 (en) | 2015-04-10 | 2024-04-17 | 10x Genomics Sweden AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
CN107850599B (zh) * | 2015-07-23 | 2021-02-09 | 新加坡国立大学 | Wbp2与her2作为共预后因子对患者分层以进行治疗 |
SG11201809913PA (en) | 2016-05-16 | 2018-12-28 | Nanostring Technologies Inc | Methods for detecting target nucleic acids in a sample |
WO2017222453A1 (en) | 2016-06-21 | 2017-12-28 | Hauling Thomas | Nucleic acid sequencing |
WO2018074865A2 (ko) * | 2016-10-21 | 2018-04-26 | 서울대학교병원 | 유방암 예후 예측용 조성물 및 방법 |
CN110225980B (zh) | 2016-11-21 | 2023-01-06 | 纳米线科技公司 | 化学组合物及其使用方法 |
KR101950717B1 (ko) * | 2016-11-23 | 2019-02-21 | 주식회사 젠큐릭스 | 유방암 환자의 화학치료 유용성 예측 방법 |
WO2018144782A1 (en) * | 2017-02-01 | 2018-08-09 | The Translational Genomics Research Institute | Methods of detecting somatic and germline variants in impure tumors |
CA3078158A1 (en) | 2017-10-06 | 2019-04-11 | Cartana Ab | Rna templated ligation |
KR102071491B1 (ko) * | 2017-11-10 | 2020-01-30 | 주식회사 디시젠 | 차세대 염기서열분석을 이용한 기계학습 기반 유방암 예후 예측 방법 및 예측 시스템 |
CN112703255A (zh) | 2018-05-14 | 2021-04-23 | 纳米线科技公司 | 化学组合物及其使用方法 |
US20210371936A1 (en) * | 2018-11-05 | 2021-12-02 | Biontech Diagnostics Gmbh | Predictive methods in breast cancer |
CN113906147B (zh) | 2019-05-31 | 2024-09-13 | 10X基因组学有限公司 | 检测目标核酸分子的方法 |
JP7352937B2 (ja) * | 2019-07-19 | 2023-09-29 | 公立大学法人福島県立医科大学 | 乳癌のサブタイプを鑑別又は分類するための鑑別マーカー遺伝子セット、方法およびキット |
EP3945136A1 (en) * | 2020-07-28 | 2022-02-02 | Hospital Clínic de Barcelona | In vitro method for the prognosis of patients suffering from her2-positive breast cancer |
US12060603B2 (en) | 2021-01-19 | 2024-08-13 | 10X Genomics, Inc. | Methods for internally controlled in situ assays using padlock probes |
AU2022419002A1 (en) * | 2021-12-20 | 2024-08-01 | Fundació De Recerca Clínic Barcelona-Institut D’Investigacions Biomèdiques August Pi I Sunyer | Development and validation of an in vitro method for the prognosis of patients suffering from her2-positive breast cancer |
CN117965734B (zh) * | 2024-02-02 | 2024-09-24 | 奥明星程(杭州)生物科技有限公司 | 一种用于检测硬纤维瘤的基因标志物、试剂盒、检测方法及应用 |
Family Cites Families (24)
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US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
AU669489B2 (en) | 1991-09-18 | 1996-06-13 | Affymax Technologies N.V. | Method of synthesizing diverse collections of oligomers |
US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
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EP0880598A4 (en) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM |
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US6750015B2 (en) * | 2000-06-28 | 2004-06-15 | Kathryn B. Horwitz | Progesterone receptor-regulated gene expression and methods related thereto |
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ES2787475T3 (es) | 2003-06-24 | 2020-10-16 | Genomic Health Inc | Predicción de probabilidad de recurrencia del cáncer |
US20050071087A1 (en) * | 2003-09-29 | 2005-03-31 | Anderson Glenda G. | Systems and methods for detecting biological features |
CA2574447A1 (en) | 2004-07-15 | 2006-01-26 | University Of Utah Research Foundation | Housekeeping genes and methods for identifying the same |
CN101061480A (zh) * | 2004-09-22 | 2007-10-24 | 三路影像公司 | 用来分析和优化用于癌症诊断的标记候选物的方法和计算机程序产品 |
US20090299640A1 (en) | 2005-11-23 | 2009-12-03 | University Of Utah Research Foundation | Methods and Compositions Involving Intrinsic Genes |
CA2640385C (en) | 2005-12-23 | 2014-07-15 | Nanostring Technologies, Inc. | Nanoreporters and methods of manufacturing and use thereof |
CA2635215C (en) | 2005-12-23 | 2016-08-30 | Nanostring Technologies, Inc. | Compositions comprising oriented, immobilized macromolecules and methods for their preparation |
AU2008237018B2 (en) | 2007-04-10 | 2014-04-03 | Bruker Spatial Biology, Inc. | Methods and computer systems for identifying target-specific sequences for use in nanoreporters |
WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
CA2698569A1 (en) * | 2007-09-06 | 2009-09-03 | Mark G. Erlander | Tumor grading and cancer prognosis |
ES2457534T3 (es) * | 2008-05-30 | 2014-04-28 | The University Of North Carolina At Chapel Hill | Perfiles de expresión génica para predecir desenlaces en cáncer de mama |
JP5836803B2 (ja) | 2008-08-14 | 2015-12-24 | ナノストリング テクノロジーズ, インコーポレイテッド | 安定したナノレポーター |
KR101864855B1 (ko) * | 2010-03-31 | 2018-07-13 | 지피돈 디아그노스틱스 게엠베하 | 내분비 치료 중 유방암 재발 예측 방법 |
-
2013
- 2013-05-22 EP EP13794236.3A patent/EP2852689B1/en active Active
- 2013-05-22 ES ES13794236T patent/ES2763931T3/es active Active
- 2013-05-22 CN CN201380038875.4A patent/CN104704128A/zh active Pending
- 2013-05-22 AU AU2013266419A patent/AU2013266419B2/en active Active
- 2013-05-22 CN CN201911216650.9A patent/CN111500718A/zh active Pending
- 2013-05-22 US US13/899,656 patent/US20130337444A1/en not_active Abandoned
- 2013-05-22 IN IN2418MUN2014 patent/IN2014MN02418A/en unknown
- 2013-05-22 CA CA2874492A patent/CA2874492C/en active Active
- 2013-05-22 WO PCT/US2013/042157 patent/WO2013177245A2/en active Application Filing
- 2013-05-22 JP JP2015514143A patent/JP6325530B2/ja active Active
- 2013-05-22 MX MX2014014275A patent/MX369628B/es active IP Right Grant
- 2013-05-22 BR BR112014029300A patent/BR112014029300A2/pt not_active Application Discontinuation
-
2014
- 2014-11-20 IL IL235795A patent/IL235795B/en active IP Right Grant
-
2020
- 2020-02-14 US US16/792,051 patent/US20200332368A1/en not_active Abandoned
-
2022
- 2022-09-29 US US17/936,745 patent/US20230272476A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN104704128A (zh) | 2015-06-10 |
JP6325530B2 (ja) | 2018-05-16 |
CA2874492A1 (en) | 2013-11-28 |
US20230272476A1 (en) | 2023-08-31 |
IL235795A0 (en) | 2015-01-29 |
EP2852689A4 (en) | 2016-05-11 |
IN2014MN02418A (es) | 2015-08-14 |
CA2874492C (en) | 2021-10-19 |
CN111500718A (zh) | 2020-08-07 |
EP2852689A2 (en) | 2015-04-01 |
IL235795B (en) | 2020-02-27 |
WO2013177245A3 (en) | 2015-01-29 |
BR112014029300A2 (pt) | 2017-07-25 |
MX2014014275A (es) | 2015-07-06 |
ES2763931T3 (es) | 2020-06-01 |
JP2015518724A (ja) | 2015-07-06 |
AU2013266419B2 (en) | 2018-09-27 |
WO2013177245A2 (en) | 2013-11-28 |
US20200332368A1 (en) | 2020-10-22 |
AU2013266419A1 (en) | 2014-12-11 |
US20130337444A1 (en) | 2013-12-19 |
EP2852689B1 (en) | 2019-12-11 |
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