DK2294215T3 - Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder - Google Patents
Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmulighederInfo
- Publication number
- DK2294215T3 DK2294215T3 DK09747388.8T DK09747388T DK2294215T3 DK 2294215 T3 DK2294215 T3 DK 2294215T3 DK 09747388 T DK09747388 T DK 09747388T DK 2294215 T3 DK2294215 T3 DK 2294215T3
- Authority
- DK
- Denmark
- Prior art keywords
- tests
- response
- cancer patients
- treatment options
- chemotherapeutic treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5257308P | 2008-05-12 | 2008-05-12 | |
| US5718208P | 2008-05-29 | 2008-05-29 | |
| PCT/US2009/043667 WO2009140304A1 (en) | 2008-05-12 | 2009-05-12 | Tests to predict responsiveness of cancer patients to chemotherapy treatment options |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2294215T3 true DK2294215T3 (da) | 2013-04-22 |
Family
ID=41319028
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09747388.8T DK2294215T3 (da) | 2008-05-12 | 2009-05-12 | Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder |
| DK12195318.6T DK2568053T3 (da) | 2008-05-12 | 2009-05-12 | Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12195318.6T DK2568053T3 (da) | 2008-05-12 | 2009-05-12 | Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090311702A1 (da) |
| EP (5) | EP2568053B1 (da) |
| CA (1) | CA2723972A1 (da) |
| DK (2) | DK2294215T3 (da) |
| ES (2) | ES2403220T3 (da) |
| HK (2) | HK1154910A1 (da) |
| WO (1) | WO2009140304A1 (da) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2258872T3 (da) * | 2002-03-13 | 2013-11-18 | Genomic Health Inc | Genekspressionsprofilering i biopsier af tumorvæv |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| EP3170906B1 (en) | 2003-06-24 | 2018-08-22 | Genomic Health, Inc. | Prediction of likelihood of cancer recurrence |
| CA2563074C (en) | 2004-04-09 | 2014-05-20 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| PL1836629T3 (pl) * | 2004-11-05 | 2020-06-15 | Genomic Health, Inc. | Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| CN103424541B (zh) | 2006-05-18 | 2018-01-30 | 分子压型学会股份有限公司 | 确定针对病状的个性化医疗介入的系统和方法 |
| EP3075864A1 (en) * | 2008-10-14 | 2016-10-05 | Caris MPI, Inc. | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| CN102301002A (zh) | 2008-11-12 | 2011-12-28 | 卡里斯生命科学卢森堡控股有限责任公司 | 使用外来体来确定表现型的方法和系统 |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| EP2502077B1 (en) * | 2009-11-20 | 2016-08-03 | The Governors of the University of Alberta | Predictive markers for taxane responsiveness and methods of use thereof |
| WO2011075724A2 (en) * | 2009-12-18 | 2011-06-23 | The University Of North Carolina At Chapel Hill | Methods and compositions for analysis of clear cell renal cell carcinoma |
| US20130011393A1 (en) * | 2010-01-12 | 2013-01-10 | Johnathan Mark Lancaster | Bad pathway gene signature |
| JP5808349B2 (ja) | 2010-03-01 | 2015-11-10 | カリス ライフ サイエンシズ スウィッツァーランド ホールディングスゲーエムベーハー | セラノーシスのためのバイオマーカー |
| JP2013526852A (ja) | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| EP2591126B1 (en) | 2010-07-07 | 2020-12-30 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| CA2824752C (en) * | 2011-01-13 | 2018-08-14 | Expression Pathology, Inc. | Bcl-2-like protein 11 srm/mrm assay |
| EP2699237A4 (en) | 2011-04-21 | 2014-11-12 | Childrens Hosp Medical Center | THERAPY FOR LEUKEMIA |
| US10342767B2 (en) | 2011-04-21 | 2019-07-09 | Children's Hospital Medical Center | Therapy for kinase-dependent malignancies |
| CN102312002A (zh) * | 2011-09-20 | 2012-01-11 | 李艳 | 一种快速检测BRCA1基因mRNA表达量的试剂盒 |
| WO2013130465A2 (en) * | 2012-02-27 | 2013-09-06 | Genomic Health, Inc. | Gene expression markers for prediction of efficacy of platinum-based chemotherapy drugs |
| WO2013170174A1 (en) * | 2012-05-10 | 2013-11-14 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Method of diagnosing, treating and determining progression and survival of cancer cells using bcl-2 antagonist of cell death (bad) pathway gene signature |
| CN102965433A (zh) * | 2012-09-29 | 2013-03-13 | 李艳 | 一种检测M BCR融合基因mRNA表达量的试剂盒 |
| EP4190918A1 (en) | 2012-11-16 | 2023-06-07 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| WO2014092572A1 (en) * | 2012-12-12 | 2014-06-19 | Universiteit Leiden | Improved methods for cancer treatment with a genotoxic agent |
| WO2015000945A1 (en) * | 2013-07-03 | 2015-01-08 | F. Hoffmann-La Roche Ag | Mrna-based gene expression for personalizing patient cancer therapy with an mdm2 antagonist |
| US9657351B2 (en) | 2013-12-06 | 2017-05-23 | Hoffman-La Roche Inc. | MRNA-based gene expression for personalizing patient cancer therapy with an MDM2 antagonist |
| KR20160132496A (ko) * | 2014-04-03 | 2016-11-18 | 인빅터스 온콜로지 피비티. 엘티디. | 초분자 조합 치료제 |
| CA2947624A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20170079979A1 (en) * | 2014-06-02 | 2017-03-23 | Children's Hospital Medical Center | Therapy for solid tumors |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| WO2018132358A1 (en) | 2017-01-10 | 2018-07-19 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| US20220249476A1 (en) * | 2018-05-11 | 2022-08-11 | Baylor College Of Medicine | MutL LOSS PREDICTS SENSITIVITY TO CDK4/6 INHIBITORS IN CANCER |
| WO2020047260A1 (en) * | 2018-08-29 | 2020-03-05 | The Regents Of The University Of Michigan | Methods of determining treatment consisting of radiation therapy and / or alkylating chemotherapy in patients suffering from cancer |
| CN109439755A (zh) * | 2018-11-30 | 2019-03-08 | 广东腾飞基因科技股份有限公司 | 一种用于检测乳腺癌相关基因表达水平的试剂盒 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627733B2 (en) * | 1993-06-14 | 2003-09-30 | Jeffrey D. Johnson | Receptor tyrosine kinase with a discoidin-type binding domain |
| JP2000038909A (ja) | 1998-07-22 | 2000-02-08 | Mitsubishi Electric Corp | バルブタイミング可変装置 |
| AU3118602A (en) | 2000-10-18 | 2002-04-29 | Genomic Health Inc | Genomic profile information systems and methods |
| DK2258872T3 (da) | 2002-03-13 | 2013-11-18 | Genomic Health Inc | Genekspressionsprofilering i biopsier af tumorvæv |
| AU2004248120B2 (en) * | 2003-05-28 | 2009-04-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| EP3170906B1 (en) | 2003-06-24 | 2018-08-22 | Genomic Health, Inc. | Prediction of likelihood of cancer recurrence |
| WO2005008213A2 (en) | 2003-07-10 | 2005-01-27 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| JP2007509613A (ja) | 2003-10-16 | 2007-04-19 | ジェノミック ヘルス， インコーポレイテッド | 遺伝子発現プロファイリングのためのｑＲＴ−ＰＣＲアッセイシステム |
| FR2863275B1 (fr) * | 2003-12-09 | 2007-08-10 | Biomerieux Sa | Procede pour le diagnostic/pronostic du cancer du sein |
| CA2563074C (en) | 2004-04-09 | 2014-05-20 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| US7587279B2 (en) | 2004-07-06 | 2009-09-08 | Genomic Health | Method for quantitative PCR data analysis system (QDAS) |
| PL1836629T3 (pl) * | 2004-11-05 | 2020-06-15 | Genomic Health, Inc. | Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu |
| WO2007057746A2 (en) * | 2005-05-27 | 2007-05-24 | Aurelium Biopharma Inc. | Focused microarray and methods of diagnosing chemotherapeutic drug resistance in a cancer cell |
| CA2611728A1 (en) * | 2005-06-08 | 2006-12-14 | Millennium Pharmaceuticals, Inc. | Methods for the identification, assessment, and treatment of patients with cancer therapy |
| WO2006135886A2 (en) * | 2005-06-13 | 2006-12-21 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| CA2612021A1 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1929306A4 (en) * | 2005-09-01 | 2009-11-11 | Precision Therapeutics Inc | CHEMOSENSIBLE ASSAYS, THE TUMOR CELLS WITH PERSISTENT PHENOTYPICAL CHARACTERISTICS |
| WO2007085497A2 (en) * | 2006-01-30 | 2007-08-02 | Epigenomics Ag | Markers for the prediction of outcome of anthracycline treatment |
| WO2009026128A2 (en) * | 2007-08-16 | 2009-02-26 | Genomic Health, Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
-
2009
- 2009-05-12 DK DK09747388.8T patent/DK2294215T3/da active
- 2009-05-12 EP EP12195318.6A patent/EP2568053B1/en active Active
- 2009-05-12 EP EP20130172903 patent/EP2641978A1/en not_active Withdrawn
- 2009-05-12 ES ES09747388T patent/ES2403220T3/es active Active
- 2009-05-12 ES ES12195318.6T patent/ES2482692T3/es active Active
- 2009-05-12 DK DK12195318.6T patent/DK2568053T3/da active
- 2009-05-12 CA CA2723972A patent/CA2723972A1/en not_active Abandoned
- 2009-05-12 US US12/464,797 patent/US20090311702A1/en not_active Abandoned
- 2009-05-12 EP EP09747388A patent/EP2294215B1/en active Active
- 2009-05-12 EP EP13159677.7A patent/EP2607497B1/en not_active Not-in-force
- 2009-05-12 EP EP13172854.5A patent/EP2641977B1/en not_active Not-in-force
- 2009-05-12 WO PCT/US2009/043667 patent/WO2009140304A1/en active Application Filing
-
2011
- 2011-08-29 HK HK11109113.0A patent/HK1154910A1/en unknown
- 2011-08-29 HK HK13107812.6A patent/HK1180727A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2294215A1 (en) | 2011-03-16 |
| EP2294215A4 (en) | 2011-06-29 |
| EP2607497A1 (en) | 2013-06-26 |
| EP2641977A1 (en) | 2013-09-25 |
| CA2723972A1 (en) | 2009-11-19 |
| ES2482692T3 (es) | 2014-08-04 |
| EP2568053B1 (en) | 2014-04-16 |
| HK1180727A1 (en) | 2013-10-25 |
| EP2607497B1 (en) | 2014-10-01 |
| DK2568053T3 (da) | 2014-07-21 |
| WO2009140304A1 (en) | 2009-11-19 |
| EP2641978A1 (en) | 2013-09-25 |
| EP2294215B1 (en) | 2013-01-16 |
| ES2403220T3 (es) | 2013-05-16 |
| EP2641977B1 (en) | 2014-09-03 |
| HK1154910A1 (en) | 2012-05-04 |
| EP2568053A1 (en) | 2013-03-13 |
| US20090311702A1 (en) | 2009-12-17 |
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