DK2568053T3 - Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder - Google Patents

Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder

Info

Publication number
DK2568053T3
DK2568053T3 DK12195318.6T DK12195318T DK2568053T3 DK 2568053 T3 DK2568053 T3 DK 2568053T3 DK 12195318 T DK12195318 T DK 12195318T DK 2568053 T3 DK2568053 T3 DK 2568053T3
Authority
DK
Denmark
Prior art keywords
tests
preventing
response
cancer patients
chemotherapeutic treatments
Prior art date
Application number
DK12195318.6T
Other languages
English (en)
Inventor
Joffre Baker
Carl Yoshizawa
Joseph Sparano
Robert Gray
Steve Shak
Original Assignee
Genomic Health Inc
Aventis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc, Aventis Inc filed Critical Genomic Health Inc
Application granted granted Critical
Publication of DK2568053T3 publication Critical patent/DK2568053T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK12195318.6T 2008-05-12 2009-05-12 Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder DK2568053T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5257308P 2008-05-12 2008-05-12
US5718208P 2008-05-29 2008-05-29
EP09747388A EP2294215B1 (en) 2008-05-12 2009-05-12 Tests to predict responsiveness of cancer patients to chemotherapy treatment options

Publications (1)

Publication Number Publication Date
DK2568053T3 true DK2568053T3 (da) 2014-07-21

Family

ID=41319028

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12195318.6T DK2568053T3 (da) 2008-05-12 2009-05-12 Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder
DK09747388.8T DK2294215T3 (da) 2008-05-12 2009-05-12 Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09747388.8T DK2294215T3 (da) 2008-05-12 2009-05-12 Tests til forudsigelse af cancerpatienters respons på forskellige kemoterapeutiske behandlingsmuligheder

Country Status (7)

Country Link
US (1) US20090311702A1 (da)
EP (5) EP2568053B1 (da)
CA (1) CA2723972A1 (da)
DK (2) DK2568053T3 (da)
ES (2) ES2403220T3 (da)
HK (2) HK1154910A1 (da)
WO (1) WO2009140304A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003078662A1 (en) * 2002-03-13 2003-09-25 Genomic Health Gene expression profiling in biopsied tumor tissues
US20040231909A1 (en) 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
EP3170906B1 (en) * 2003-06-24 2018-08-22 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
US7871769B2 (en) 2004-04-09 2011-01-18 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
JP5020088B2 (ja) * 2004-11-05 2012-09-05 ジェノミック ヘルス, インコーポレイテッド 遺伝子発現マーカーを使用する、化学療法に対する反応の予測
EP2032980A4 (en) 2006-05-18 2012-01-04 Molecular Profiling Inst Inc SYSTEM AND METHOD FOR DETERMINING AN INDIVIDUALIZED MEDICAL INTERVENTION FOR A PATHOLOGY
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
EP3075864A1 (en) * 2008-10-14 2016-10-05 Caris MPI, Inc. Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type
US7897356B2 (en) 2008-11-12 2011-03-01 Caris Life Sciences Methods and systems of using exosomes for determining phenotypes
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
WO2011060537A1 (en) 2009-11-20 2011-05-26 The Governors Of The University Of Alberta Predictive markers for taxane responsiveness and methods of use thereof
US20130005597A1 (en) * 2009-12-18 2013-01-03 Rathmell W Kimryn Methods and compositions for analysis of clear cell renal cell carcinoma (ccrcc)
US20130011393A1 (en) * 2010-01-12 2013-01-10 Johnathan Mark Lancaster Bad pathway gene signature
JP2013526852A (ja) 2010-04-06 2013-06-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス 疾患に対する循環バイオマーカー
WO2012006447A2 (en) 2010-07-07 2012-01-12 Myriad Genetics, Inc. Gene signatures for cancer prognosis
CA2809829A1 (en) 2010-08-30 2012-03-08 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
JP6046053B2 (ja) 2011-01-13 2016-12-14 エクスプレッション、パソロジー、インコーポレイテッドExpression Pathology, Inc. Bcl−2様タンパク質11のSRM/MRMアッセイ
US10342767B2 (en) 2011-04-21 2019-07-09 Children's Hospital Medical Center Therapy for kinase-dependent malignancies
EP2699237A4 (en) 2011-04-21 2014-11-12 Childrens Hosp Medical Center THERAPY FOR LEUKEMIA
CN102312002A (zh) * 2011-09-20 2012-01-11 李艳 一种快速检测BRCA1基因mRNA表达量的试剂盒
WO2013130465A2 (en) * 2012-02-27 2013-09-06 Genomic Health, Inc. Gene expression markers for prediction of efficacy of platinum-based chemotherapy drugs
WO2013170174A1 (en) * 2012-05-10 2013-11-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Method of diagnosing, treating and determining progression and survival of cancer cells using bcl-2 antagonist of cell death (bad) pathway gene signature
CN102965433A (zh) * 2012-09-29 2013-03-13 李艳 一种检测M BCR融合基因mRNA表达量的试剂盒
EP2920322B1 (en) 2012-11-16 2023-01-11 Myriad Genetics, Inc. Gene signatures for cancer prognosis
WO2014092572A1 (en) * 2012-12-12 2014-06-19 Universiteit Leiden Improved methods for cancer treatment with a genotoxic agent
JP6461126B2 (ja) * 2013-07-03 2019-01-30 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Mdm2アンタゴニストを用いた患者のがん治療法をパーソナライズするためのmrnaベースの遺伝子発現
US9657351B2 (en) 2013-12-06 2017-05-23 Hoffman-La Roche Inc. MRNA-based gene expression for personalizing patient cancer therapy with an MDM2 antagonist
CA2944401A1 (en) * 2014-04-03 2015-10-08 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics
EP3623482A1 (en) 2014-05-13 2020-03-18 Myriad Genetics, Inc. Gene signatures for cancer prognosis
US20170079979A1 (en) * 2014-06-02 2017-03-23 Children's Hospital Medical Center Therapy for solid tumors
GB201501930D0 (en) * 2015-02-05 2015-03-25 Univ London Queen Mary Biomarkers for pancreatic cancer
US11136583B2 (en) 2017-01-10 2021-10-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
US20220249476A1 (en) * 2018-05-11 2022-08-11 Baylor College Of Medicine MutL LOSS PREDICTS SENSITIVITY TO CDK4/6 INHIBITORS IN CANCER
WO2020047260A1 (en) * 2018-08-29 2020-03-05 The Regents Of The University Of Michigan Methods of determining treatment consisting of radiation therapy and / or alkylating chemotherapy in patients suffering from cancer
CN109439755A (zh) * 2018-11-30 2019-03-08 广东腾飞基因科技股份有限公司 一种用于检测乳腺癌相关基因表达水平的试剂盒

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627733B2 (en) * 1993-06-14 2003-09-30 Jeffrey D. Johnson Receptor tyrosine kinase with a discoidin-type binding domain
JP2000038909A (ja) 1998-07-22 2000-02-08 Mitsubishi Electric Corp バルブタイミング可変装置
AU3118602A (en) 2000-10-18 2002-04-29 Genomic Health Inc Genomic profile information systems and methods
WO2003078662A1 (en) 2002-03-13 2003-09-25 Genomic Health Gene expression profiling in biopsied tumor tissues
WO2004111603A2 (en) * 2003-05-28 2004-12-23 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
EP3170906B1 (en) 2003-06-24 2018-08-22 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
ES2905579T3 (es) 2003-07-10 2022-04-11 Genomic Health Inc Algoritmo del perfil de expresión y prueba para el pronóstico de la recaída del cáncer de mama
EP1678327A4 (en) 2003-10-16 2007-10-10 Genomic Health Inc QRT-PCR TEST SYSTEM FOR GENE EXPRESSION PROFILING
FR2863275B1 (fr) * 2003-12-09 2007-08-10 Biomerieux Sa Procede pour le diagnostic/pronostic du cancer du sein
US7871769B2 (en) * 2004-04-09 2011-01-18 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US7587279B2 (en) 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
JP5020088B2 (ja) * 2004-11-05 2012-09-05 ジェノミック ヘルス, インコーポレイテッド 遺伝子発現マーカーを使用する、化学療法に対する反応の予測
US20060275810A1 (en) * 2005-05-27 2006-12-07 Elias Georges Focused microarray and methods of diagnosing chemotherapeutic drug resistance in a cancer cell
US8278038B2 (en) * 2005-06-08 2012-10-02 Millennium Pharmaceuticals, Inc. Methods for the identification, assessment, and treatment of patients with cancer therapy
US20070099209A1 (en) * 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070105133A1 (en) * 2005-06-13 2007-05-10 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
WO2007028146A2 (en) * 2005-09-01 2007-03-08 Precision Therapeutics, Inc. Chemo-sensitivity assays using tumor cells exhibiting persistent phenotypic characteristics
WO2007085497A2 (en) * 2006-01-30 2007-08-02 Epigenomics Ag Markers for the prediction of outcome of anthracycline treatment
WO2009026128A2 (en) * 2007-08-16 2009-02-26 Genomic Health, Inc. Gene expression markers of recurrence risk in cancer patients after chemotherapy

Also Published As

Publication number Publication date
EP2607497B1 (en) 2014-10-01
US20090311702A1 (en) 2009-12-17
WO2009140304A1 (en) 2009-11-19
HK1154910A1 (en) 2012-05-04
EP2641977B1 (en) 2014-09-03
ES2482692T3 (es) 2014-08-04
EP2568053A1 (en) 2013-03-13
EP2568053B1 (en) 2014-04-16
DK2294215T3 (da) 2013-04-22
EP2641977A1 (en) 2013-09-25
EP2294215A1 (en) 2011-03-16
EP2607497A1 (en) 2013-06-26
EP2294215B1 (en) 2013-01-16
HK1180727A1 (en) 2013-10-25
CA2723972A1 (en) 2009-11-19
ES2403220T3 (es) 2013-05-16
EP2641978A1 (en) 2013-09-25
EP2294215A4 (en) 2011-06-29

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