ES2533095T3 - Agonistas de receptores de esfingosina-1-fosfato - Google Patents

Agonistas de receptores de esfingosina-1-fosfato Download PDF

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Publication number
ES2533095T3
ES2533095T3 ES10742067.1T ES10742067T ES2533095T3 ES 2533095 T3 ES2533095 T3 ES 2533095T3 ES 10742067 T ES10742067 T ES 10742067T ES 2533095 T3 ES2533095 T3 ES 2533095T3
Authority
ES
Spain
Prior art keywords
phenyl
acid
oxadiazol
trifluoromethyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10742067.1T
Other languages
English (en)
Spanish (es)
Inventor
John L. Gilmore
James E. Sheppeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ES2533095T3 publication Critical patent/ES2533095T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES10742067.1T 2009-08-07 2010-08-06 Agonistas de receptores de esfingosina-1-fosfato Active ES2533095T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23205409P 2009-08-07 2009-08-07
US232054P 2009-08-07
PCT/US2010/044627 WO2011017578A1 (en) 2009-08-07 2010-08-06 Sphingosine-1-phosphate receptor agonists

Publications (1)

Publication Number Publication Date
ES2533095T3 true ES2533095T3 (es) 2015-04-07

Family

ID=43029859

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10742067.1T Active ES2533095T3 (es) 2009-08-07 2010-08-06 Agonistas de receptores de esfingosina-1-fosfato

Country Status (19)

Country Link
US (1) US8399451B2 (enExample)
EP (1) EP2462139B1 (enExample)
JP (1) JP5602230B2 (enExample)
KR (1) KR20120108963A (enExample)
CN (1) CN102548989A (enExample)
AR (1) AR077819A1 (enExample)
AU (1) AU2010279354A1 (enExample)
BR (1) BR112012002824A2 (enExample)
CA (1) CA2770194A1 (enExample)
CL (1) CL2012000326A1 (enExample)
CO (1) CO6430439A2 (enExample)
EA (1) EA201270266A1 (enExample)
ES (1) ES2533095T3 (enExample)
MX (1) MX2012001160A (enExample)
PE (1) PE20120732A1 (enExample)
SG (1) SG177691A1 (enExample)
TW (1) TW201109323A (enExample)
WO (1) WO2011017578A1 (enExample)
ZA (1) ZA201200641B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100029685A1 (en) * 2006-10-25 2010-02-04 Neurosearch A/S Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
WO2011133734A1 (en) * 2010-04-23 2011-10-27 Bristol-Myers Squibb Company 4 - (5 - isoxazolyl or 5 - pyrrazolyl -1,2,4- oxadiazol - 3 - yl) -mandelic acid amides as sphingosin- 1 - phosphate 1 rreceptor agonists
ES2539256T3 (es) 2010-07-20 2015-06-29 Bristol-Myers Squibb Company Compuestos de 3-fenil-1,2,4-oxadiazol sustituidos
US9187437B2 (en) 2010-09-24 2015-11-17 Bristol-Myers Squibb Company Substituted oxadiazole compounds
ES2525298T3 (es) 2010-11-03 2014-12-19 Bristol-Myers Squibb Company Compuestos heterocíclicos como agonistas del S1P1 para el tratamiento de enfermedades autoinmunes y vasculares
UY35338A (es) 2013-02-21 2014-08-29 Bristol Myers Squibb Company Una Corporación Del Estado De Delaware Compuestos bicíclicos moduladores de la actividad de s1p1 y composiciones farmacéuticas que los contienen
UY36274A (es) 2014-08-20 2016-02-29 Bristol Myers Squibb Company Una Corporación Del Estado De Delaware Compuestos bicíclicos sustituidos como agonistas selectivos de la actividad del receptor s1p1 acoplado a la proteína g
TW202023386A (zh) * 2018-09-13 2020-07-01 瑞士商先正達合夥公司 殺有害生物活性唑-醯胺化合物
CN114181276A (zh) * 2021-12-17 2022-03-15 安徽大学 硫酯肽合成方法

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Also Published As

Publication number Publication date
CL2012000326A1 (es) 2012-10-19
CN102548989A (zh) 2012-07-04
WO2011017578A1 (en) 2011-02-10
AR077819A1 (es) 2011-09-28
BR112012002824A2 (pt) 2019-09-24
PE20120732A1 (es) 2012-06-20
US20110190255A1 (en) 2011-08-04
JP2013501729A (ja) 2013-01-17
ZA201200641B (en) 2013-06-26
AU2010279354A1 (en) 2012-02-09
CA2770194A1 (en) 2011-02-10
KR20120108963A (ko) 2012-10-05
SG177691A1 (en) 2012-02-28
EA201270266A1 (ru) 2012-07-30
US8399451B2 (en) 2013-03-19
TW201109323A (en) 2011-03-16
EP2462139B1 (en) 2015-01-14
EP2462139A1 (en) 2012-06-13
JP5602230B2 (ja) 2014-10-08
CO6430439A2 (es) 2012-04-30
MX2012001160A (es) 2012-02-13

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