ES2266904T3 - Polimeros polivalentes, metodos y composiciones. - Google Patents

Info

Publication number

ES2266904T3

ES2266904T3 ES03795628T ES03795628T ES2266904T3 ES 2266904 T3 ES2266904 T3 ES 2266904T3 ES 03795628 T ES03795628 T ES 03795628T ES 03795628 T ES03795628 T ES 03795628T ES 2266904 T3 ES2266904 T3 ES 2266904T3

Authority

ES

Spain

Prior art keywords

alkyl

polymer

composition

mixture

monomer

Prior art date

2002-09-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Lifetime

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• 229920000642 polymer Polymers 0.000 title claims abstract description 423
• 239000000203 mixture Substances 0.000 title claims abstract description 408
• 238000000034 method Methods 0.000 title claims description 35
• 239000000178 monomer Substances 0.000 claims abstract description 240
• 125000000217 alkyl group Chemical group 0.000 claims abstract description 97
• 229920002554 vinyl polymer Polymers 0.000 claims abstract description 83
• 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims abstract description 78
• 239000004094 surface-active agent Substances 0.000 claims abstract description 71
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 37
• 150000001875 compounds Chemical class 0.000 claims abstract description 27
• 150000002148 esters Chemical class 0.000 claims abstract description 27
• 238000006116 polymerization reaction Methods 0.000 claims abstract description 25
• 125000003118 aryl group Chemical group 0.000 claims abstract description 23
• 230000002209 hydrophobic effect Effects 0.000 claims abstract description 23
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 18
• 125000005702 oxyalkylene group Chemical group 0.000 claims abstract description 12
• 125000001424 substituent group Chemical group 0.000 claims abstract description 12
• 229920001400 block copolymer Polymers 0.000 claims abstract description 10
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract description 10
• 229920001519 homopolymer Polymers 0.000 claims abstract description 10
• 229920005604 random copolymer Polymers 0.000 claims abstract description 10
• 125000003545 alkoxy group Chemical group 0.000 claims abstract description 9
• 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims abstract description 8
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 7
• 125000005843 halogen group Chemical group 0.000 claims abstract description 6
• -1 2-pyrrolidonyl Chemical group 0.000 claims description 186
• 210000004209 hair Anatomy 0.000 claims description 148
• 239000003795 chemical substances by application Substances 0.000 claims description 130
• 239000000839 emulsion Substances 0.000 claims description 90
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 75
• 238000009472 formulation Methods 0.000 claims description 58
• 229910052757 nitrogen Inorganic materials 0.000 claims description 56
• NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 54
• 150000003839 salts Chemical group 0.000 claims description 40
• 230000003750 conditioning effect Effects 0.000 claims description 36
• 239000000126 substance Substances 0.000 claims description 32
• 238000004140 cleaning Methods 0.000 claims description 30
• 239000003381 stabilizer Substances 0.000 claims description 30
• 239000002562 thickening agent Substances 0.000 claims description 30
• 239000002537 cosmetic Substances 0.000 claims description 28
• 239000003921 oil Substances 0.000 claims description 28
• 229920001577 copolymer Polymers 0.000 claims description 26
• 239000002904 solvent Substances 0.000 claims description 25
• 239000000463 material Substances 0.000 claims description 23
• 239000007788 liquid Substances 0.000 claims description 22
• 238000004132 cross linking Methods 0.000 claims description 21
• HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims description 19
• 239000007787 solid Substances 0.000 claims description 19
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 18
• 239000010408 film Substances 0.000 claims description 18
• 239000003995 emulsifying agent Substances 0.000 claims description 16
• 238000007720 emulsion polymerization reaction Methods 0.000 claims description 16
• CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 15
• 150000002734 metacrylic acid derivatives Polymers 0.000 claims description 15
• CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical group OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 14
• 230000008569 process Effects 0.000 claims description 14
• 239000006254 rheological additive Substances 0.000 claims description 14
• 238000011282 treatment Methods 0.000 claims description 14
• 238000000576 coating method Methods 0.000 claims description 13
• 239000006260 foam Substances 0.000 claims description 13
• 239000002736 nonionic surfactant Substances 0.000 claims description 13
• 150000005846 sugar alcohols Polymers 0.000 claims description 13
• 150000001252 acrylic acid derivatives Polymers 0.000 claims description 12
• 239000003945 anionic surfactant Substances 0.000 claims description 12
• 239000012986 chain transfer agent Substances 0.000 claims description 12
• 239000003999 initiator Substances 0.000 claims description 12
• 125000000129 anionic group Chemical group 0.000 claims description 11
• 238000002360 preparation method Methods 0.000 claims description 11
• 239000003981 vehicle Substances 0.000 claims description 11
• HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 10
• 150000003856 quaternary ammonium compounds Chemical class 0.000 claims description 10
• 238000000518 rheometry Methods 0.000 claims description 10
• 239000004909 Moisturizer Substances 0.000 claims description 9
• 238000004519 manufacturing process Methods 0.000 claims description 9
• 230000001333 moisturizer Effects 0.000 claims description 9
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 9
• 239000003380 propellant Substances 0.000 claims description 9
• 239000000375 suspending agent Substances 0.000 claims description 9
• 238000006243 chemical reaction Methods 0.000 claims description 8
• 239000007921 spray Substances 0.000 claims description 8
• NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 7
• 125000004103 aminoalkyl group Chemical group 0.000 claims description 7
• 239000011248 coating agent Substances 0.000 claims description 7
• 125000000623 heterocyclic group Chemical group 0.000 claims description 7
• 230000004048 modification Effects 0.000 claims description 7
• 238000012986 modification Methods 0.000 claims description 7
• SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 6
• 125000005907 alkyl ester group Chemical group 0.000 claims description 6
• 239000006172 buffering agent Substances 0.000 claims description 6
• 229910052799 carbon Inorganic materials 0.000 claims description 6
• 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 6
• 229910052736 halogen Inorganic materials 0.000 claims description 6
• 230000036541 health Effects 0.000 claims description 6
• 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 6
• 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 6
• CMVNWVONJDMTSH-UHFFFAOYSA-N 7-bromo-2-methyl-1h-quinazolin-4-one Polymers C1=CC(Br)=CC2=NC(C)=NC(O)=C21 CMVNWVONJDMTSH-UHFFFAOYSA-N 0.000 claims description 5
• 235000014698 Brassica juncea var multisecta Nutrition 0.000 claims description 5
• 235000006008 Brassica napus var napus Nutrition 0.000 claims description 5
• 240000000385 Brassica napus var. napus Species 0.000 claims description 5
• 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 claims description 5
• 235000004977 Brassica sinapistrum Nutrition 0.000 claims description 5
• 239000002280 amphoteric surfactant Substances 0.000 claims description 5
• 239000004359 castor oil Substances 0.000 claims description 5
• 235000019438 castor oil Nutrition 0.000 claims description 5
• 235000012000 cholesterol Nutrition 0.000 claims description 5
• 239000000834 fixative Substances 0.000 claims description 5
• ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 5
• 229920006254 polymer film Polymers 0.000 claims description 5
• 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 5
• UROPHWSHWQXFDR-UHFFFAOYSA-N 2-methylprop-2-enoic acid;phenol Chemical compound CC(=C)C(O)=O.OC1=CC=CC=C1 UROPHWSHWQXFDR-UHFFFAOYSA-N 0.000 claims description 4
• WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical group CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 4
• 125000001204 arachidyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
• 239000002738 chelating agent Substances 0.000 claims description 4
• 239000002270 dispersing agent Substances 0.000 claims description 4
• HJZOFAWRMPYCHL-UHFFFAOYSA-N octacosyl prop-2-enoate Polymers CCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C=C HJZOFAWRMPYCHL-UHFFFAOYSA-N 0.000 claims description 4
• 239000004753 textile Substances 0.000 claims description 4
• 125000004209 (C1-C8) alkyl group Chemical group 0.000 claims description 3
• JTHZUSWLNCPZLX-UHFFFAOYSA-N 6-fluoro-3-methyl-2h-indazole Polymers FC1=CC=C2C(C)=NNC2=C1 JTHZUSWLNCPZLX-UHFFFAOYSA-N 0.000 claims description 3
• 125000005250 alkyl acrylate group Chemical group 0.000 claims description 3
• OCDWICPYKQMQSQ-UHFFFAOYSA-N docosyl 2-methylprop-2-enoate Polymers CCCCCCCCCCCCCCCCCCCCCCOC(=O)C(C)=C OCDWICPYKQMQSQ-UHFFFAOYSA-N 0.000 claims description 3
• 230000001804 emulsifying effect Effects 0.000 claims description 3
• 229910052739 hydrogen Inorganic materials 0.000 claims description 3
• 229910021645 metal ion Inorganic materials 0.000 claims description 3
• FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical group CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims description 3
• 101150009274 nhr-1 gene Proteins 0.000 claims description 3
• 239000003973 paint Substances 0.000 claims description 3
• 239000012736 aqueous medium Substances 0.000 claims description 2
• 239000008406 cosmetic ingredient Substances 0.000 claims description 2
• 125000004185 ester group Chemical group 0.000 claims description 2
• 125000002819 montanyl group Polymers [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
• FSAJWMJJORKPKS-UHFFFAOYSA-N octadecyl prop-2-enoate Polymers CCCCCCCCCCCCCCCCCCOC(=O)C=C FSAJWMJJORKPKS-UHFFFAOYSA-N 0.000 claims description 2
• GMMVDHHXYPDRJR-UHFFFAOYSA-N hexacosyl prop-2-enoate Polymers CCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C=C GMMVDHHXYPDRJR-UHFFFAOYSA-N 0.000 claims 3
• BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims 2
• NGYRYRBDIPYKTL-UHFFFAOYSA-N icosyl prop-2-enoate Polymers CCCCCCCCCCCCCCCCCCCCOC(=O)C=C NGYRYRBDIPYKTL-UHFFFAOYSA-N 0.000 claims 2
• ACVYVLVWPXVTIT-UHFFFAOYSA-M phosphinate Chemical compound [O-][PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-M 0.000 claims 2
• OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical compound OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 claims 2
• 125000000923 (C1-C30) alkyl group Chemical group 0.000 abstract 3
• 125000004417 unsaturated alkyl group Chemical group 0.000 abstract 2
• 239000000047 product Substances 0.000 description 161
• 125000002091 cationic group Chemical group 0.000 description 139
• 239000004615 ingredient Substances 0.000 description 118
• 239000002253 acid Substances 0.000 description 78
• 239000000499 gel Substances 0.000 description 71
• OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 63
• VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 53
• 239000002453 shampoo Substances 0.000 description 52
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 44
• 239000004480 active ingredient Substances 0.000 description 41
• 235000002639 sodium chloride Nutrition 0.000 description 40
• 238000002156 mixing Methods 0.000 description 38
• KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 33
• 229920001296 polysiloxane Polymers 0.000 description 29
• AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 28
• DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 27
• 235000019198 oils Nutrition 0.000 description 26
• LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 23
• 239000006071 cream Substances 0.000 description 21
• 239000008367 deionised water Substances 0.000 description 20
• 229910021641 deionized water Inorganic materials 0.000 description 20
• 229920000036 polyvinylpyrrolidone Polymers 0.000 description 20
• 239000001267 polyvinylpyrrolidone Substances 0.000 description 20
• 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 20
• 239000003755 preservative agent Substances 0.000 description 20
• 239000011734 sodium Substances 0.000 description 20
• 229910052708 sodium Inorganic materials 0.000 description 20
• DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 19
• 230000000670 limiting effect Effects 0.000 description 19
• 239000012071 phase Substances 0.000 description 19
• 238000003860 storage Methods 0.000 description 19
• 239000004744 fabric Substances 0.000 description 18
• 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 17
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 16
• WOWHHFRSBJGXCM-UHFFFAOYSA-M cetyltrimethylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+](C)(C)C WOWHHFRSBJGXCM-UHFFFAOYSA-M 0.000 description 16
• 235000013870 dimethyl polysiloxane Nutrition 0.000 description 16
• 239000000975 dye Substances 0.000 description 16
• 230000006870 function Effects 0.000 description 16
• 230000002335 preservative effect Effects 0.000 description 16
• RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 15
• 230000002378 acidificating effect Effects 0.000 description 15
• 239000003205 fragrance Substances 0.000 description 15
• 239000004205 dimethyl polysiloxane Substances 0.000 description 14
• 239000002216 antistatic agent Substances 0.000 description 13
• 230000003247 decreasing effect Effects 0.000 description 13
• 229940008099 dimethicone Drugs 0.000 description 13
• 239000006210 lotion Substances 0.000 description 13
• 150000007513 acids Chemical class 0.000 description 12
• JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 12
• 239000002245 particle Substances 0.000 description 12
• 150000001412 amines Chemical class 0.000 description 11
• 235000015165 citric acid Nutrition 0.000 description 11
• 230000000052 comparative effect Effects 0.000 description 11
• 230000001965 increasing effect Effects 0.000 description 11
• 239000002674 ointment Substances 0.000 description 11
• 229920002472 Starch Polymers 0.000 description 10
• 239000000654 additive Substances 0.000 description 10
• 150000001298 alcohols Chemical class 0.000 description 10
• 235000014113 dietary fatty acids Nutrition 0.000 description 10
• 239000000194 fatty acid Substances 0.000 description 10
• 229930195729 fatty acid Natural products 0.000 description 10
• KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 10
• WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 10
• 235000018102 proteins Nutrition 0.000 description 10
• 102000004169 proteins and genes Human genes 0.000 description 10
• 108090000623 proteins and genes Proteins 0.000 description 10
• 239000000243 solution Substances 0.000 description 10
• 235000019698 starch Nutrition 0.000 description 10
• 238000012546 transfer Methods 0.000 description 10
• ZPFAVCIQZKRBGF-UHFFFAOYSA-N 1,3,2-dioxathiolane 2,2-dioxide Chemical compound O=S1(=O)OCCO1 ZPFAVCIQZKRBGF-UHFFFAOYSA-N 0.000 description 9
• IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 9
• HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
• 230000003115 biocidal effect Effects 0.000 description 9
• 125000004432 carbon atom Chemical group C* 0.000 description 9
• 239000000843 powder Substances 0.000 description 9
• 239000008107 starch Substances 0.000 description 9
• JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 description 8
• QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 8
• 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 8
• 229920003171 Poly (ethylene oxide) Polymers 0.000 description 8
• 239000003093 cationic surfactant Substances 0.000 description 8
• MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 8
• 239000003814 drug Substances 0.000 description 8
• 150000002170 ethers Chemical class 0.000 description 8
• 239000012530 fluid Substances 0.000 description 8
• 210000000282 nail Anatomy 0.000 description 8
• 239000000049 pigment Substances 0.000 description 8
• 125000001453 quaternary ammonium group Chemical group 0.000 description 8
• 239000011541 reaction mixture Substances 0.000 description 8
• 238000003756 stirring Methods 0.000 description 8
• 239000003760 tallow Substances 0.000 description 8
• 230000000699 topical effect Effects 0.000 description 8
• 239000001993 wax Substances 0.000 description 8
• JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical class OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 7
• ATVJXMYDOSMEPO-UHFFFAOYSA-N 3-prop-2-enoxyprop-1-ene Chemical compound C=CCOCC=C ATVJXMYDOSMEPO-UHFFFAOYSA-N 0.000 description 7
• NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 7
• PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical class [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 7
• 239000004902 Softening Agent Substances 0.000 description 7
• 239000003082 abrasive agent Substances 0.000 description 7
• 125000002252 acyl group Chemical group 0.000 description 7
• 229940061720 alpha hydroxy acid Drugs 0.000 description 7
• 150000001280 alpha hydroxy acids Chemical class 0.000 description 7
• 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 7
• 210000002683 foot Anatomy 0.000 description 7
• 235000011187 glycerol Nutrition 0.000 description 7
• 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 7
• 229910052500 inorganic mineral Inorganic materials 0.000 description 7
• 230000014759 maintenance of location Effects 0.000 description 7
• 230000007935 neutral effect Effects 0.000 description 7
• 150000003242 quaternary ammonium salts Chemical class 0.000 description 7
• OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 6
• QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
• 102000008186 Collagen Human genes 0.000 description 6
• 108010035532 Collagen Proteins 0.000 description 6
• QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 6
• MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 6
• 239000004354 Hydroxyethyl cellulose Substances 0.000 description 6
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