ES2061465T3 - Derivados de oxadiazolilalquilpurina, su preparacion y su aplicacion en productos farmaceuticos. - Google Patents

Derivados de oxadiazolilalquilpurina, su preparacion y su aplicacion en productos farmaceuticos.

Info

Publication number
ES2061465T3
ES2061465T3 ES87114798T ES87114798T ES2061465T3 ES 2061465 T3 ES2061465 T3 ES 2061465T3 ES 87114798 T ES87114798 T ES 87114798T ES 87114798 T ES87114798 T ES 87114798T ES 2061465 T3 ES2061465 T3 ES 2061465T3
Authority
ES
Spain
Prior art keywords
derivatives
alkyl
alkylpurine
oxadiazolyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87114798T
Other languages
English (en)
Spanish (es)
Inventor
Dezso Dr Dipl-Ing Ch Korbonits
Emil Dr Minker
Zoltan Dr Chem Vargai
Gergely Dr Dipl-Ing Chem Heja
Gabor Dr Dipl-Ing Chem Kovacs
Agnes Dr Dipl-Ing Ch Gottsegen
Sandor Dr Dipl-Ing Chem Antus
Sandor Dr Virag
Andrea Dipl-Ing Ch Bolehovszky
Jeno Dr Marton
Nee Kellner Katalin Marmarosi
Lorand Dr Debreczeni
Laszlo Dr Tardos
Peter Dr Kormoczy
Vera Dr Gergely
Gabor Dr Chem Horvath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of ES2061465T3 publication Critical patent/ES2061465T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
ES87114798T 1986-10-09 1987-10-09 Derivados de oxadiazolilalquilpurina, su preparacion y su aplicacion en productos farmaceuticos. Expired - Lifetime ES2061465T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU864230A HU197574B (en) 1986-10-09 1986-10-09 Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Publications (1)

Publication Number Publication Date
ES2061465T3 true ES2061465T3 (es) 1994-12-16

Family

ID=10967389

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87114798T Expired - Lifetime ES2061465T3 (es) 1986-10-09 1987-10-09 Derivados de oxadiazolilalquilpurina, su preparacion y su aplicacion en productos farmaceuticos.

Country Status (28)

Country Link
US (1) US4840949A (en, 2012)
EP (1) EP0264081B1 (en, 2012)
JP (1) JPS63107980A (en, 2012)
KR (1) KR960003612B1 (en, 2012)
CN (1) CN1018644B (en, 2012)
AT (1) ATE99685T1 (en, 2012)
AU (1) AU595384B2 (en, 2012)
BG (1) BG60403B2 (en, 2012)
CS (1) CS276993B6 (en, 2012)
CY (1) CY1843A (en, 2012)
DD (1) DD262658A5 (en, 2012)
DE (1) DE3788701D1 (en, 2012)
DK (1) DK167806B1 (en, 2012)
ES (1) ES2061465T3 (en, 2012)
FI (1) FI87215C (en, 2012)
GE (3) GEP19970842B (en, 2012)
HK (1) HK78995A (en, 2012)
HU (1) HU197574B (en, 2012)
IL (1) IL84030A (en, 2012)
LT (1) LT3685B (en, 2012)
LV (1) LV10868B (en, 2012)
NO (1) NO166323C (en, 2012)
PL (2) PL268147A1 (en, 2012)
RU (1) RU2007404C1 (en, 2012)
SU (2) SU1602862A1 (en, 2012)
UA (2) UA5572A1 (en, 2012)
YU (1) YU47545B (en, 2012)
ZA (1) ZA877333B (en, 2012)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
IT1199320B (it) * 1986-12-16 1988-12-30 Malesci Sas 8-azaxantine alchilaminoalchil o eterociclilalchil sostituite sul nucleo triazolico,loro sali fisiologicamente accettabili,loro composizioni farmaceutiche ad attivita'antibroncospastica e relativo procedimento di preparazione
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
HUP9700654A2 (hu) * 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
US8106234B2 (en) * 2009-05-07 2012-01-31 OptMed, Inc Methylidene malonate process
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
CA2853073A1 (en) 2011-10-19 2013-04-25 Bioformix Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
JP6345644B2 (ja) 2012-03-30 2018-06-20 シラス・インコーポレイテッド インク配合物およびコーティング配合物ならびにこれらを作製するための重合性の系
US10913875B2 (en) 2012-03-30 2021-02-09 Sirrus, Inc. Composite and laminate articles and polymerizable systems for producing the same
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
EP2920231B1 (en) 2012-11-16 2020-05-06 Sirrus, Inc. Plastics bonding systems and methods
EP3712928A1 (en) 2012-11-30 2020-09-23 Sirrus, Inc. Composite compositions for electronics applications
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
RU2754735C1 (ru) * 2020-12-14 2021-09-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный технический университет" ФГБОУВО "ЯГТУ" Способ получения 3,5-дизамещенных 1,2,4-оксадиазолов, содержащих алкенильный фрагмент

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Also Published As

Publication number Publication date
JPH0546348B2 (en, 2012) 1993-07-13
FI87215C (fi) 1992-12-10
HU197574B (en) 1989-04-28
FI874456A7 (fi) 1988-04-10
NO874216D0 (no) 1987-10-08
DE3788701D1 (de) 1994-02-17
CN87107785A (zh) 1988-07-20
EP0264081B1 (de) 1994-01-05
CY1843A (en) 1996-03-08
LTIP1455A (en) 1995-05-25
SU1635901A3 (ru) 1991-03-15
US4840949A (en) 1989-06-20
NO166323B (no) 1991-03-25
KR960003612B1 (ko) 1996-03-20
UA5572A1 (uk) 1994-12-28
IL84030A0 (en) 1988-02-29
LT3685B (en) 1996-01-25
GEP19970817B (en) 1997-01-30
JPS63107980A (ja) 1988-05-12
IL84030A (en) 1991-01-31
ZA877333B (en) 1988-04-08
DD262658A5 (de) 1988-12-07
GEP19970842B (en) 1997-02-06
YU185787A (sh) 1993-05-28
DK527087A (da) 1988-04-10
UA26368A (uk) 1999-08-30
CN1018644B (zh) 1992-10-14
GEP19960657B (en) 1996-12-24
CS732787A3 (en) 1992-04-15
HUT46003A (en) 1988-09-28
AU595384B2 (en) 1990-03-29
DK527087D0 (da) 1987-10-08
EP0264081A2 (de) 1988-04-20
KR890006647A (ko) 1989-06-15
NO874216L (no) 1988-04-11
PL151110B1 (en, 2012) 1990-08-31
YU47545B (sh) 1995-10-03
BG60403B2 (bg) 1995-02-28
LV10868A (lv) 1995-10-20
FI874456A0 (fi) 1987-10-09
PL151206B1 (en) 1990-08-31
EP0264081A3 (en) 1989-11-15
LV10868B (en) 1996-06-20
AU7946287A (en) 1988-04-14
DK167806B1 (da) 1993-12-20
PL268147A1 (en) 1988-09-01
RU2007404C1 (ru) 1994-02-15
CS276993B6 (en) 1992-11-18
SU1602862A1 (ru) 1990-10-30
NO166323C (no) 1991-07-03
FI87215B (fi) 1992-08-31
ATE99685T1 (de) 1994-01-15
HK78995A (en) 1995-05-26

Similar Documents

Publication Publication Date Title
ES2061465T3 (es) Derivados de oxadiazolilalquilpurina, su preparacion y su aplicacion en productos farmaceuticos.
ES2076147T3 (es) Nuevos derivados de amina ciclicos, medicamento que contiene estos compuestos y procedimiento para su preparacion.
ES2058527T3 (es) Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen.
AR004219A1 (es) Nuevos derivados de quinazolina, procedimientos para su preparacion, composiciones que los contienen y su uso en la preparacion de medicamentos,particularmente en el tratamiento de trastornos inflamatorios
ES2104887T3 (es) Derivados de acridina.
PT88603A (pt) Immunomodulatory azapiranes
AR012315A1 (es) Derivados de ditiolan y el uso de los mismos en la fabricacion de un medicamento.
ES2062460T3 (es) Nuevos derivados de la isoindolona, su preparacion y las composiciones farmaceuticas que les contienen.
ES2084944T3 (es) Amidas terapeuticas.
DK160877C (da) Fremgangsmaade til fremstilling af 2-penemforbindelser
ES2054725T3 (es) Heteroaromatos anulares de cinco miembros de p-fenoxi-fenoximetilo.
ES2067448T3 (es) Amidas de acidos piridina-2,4- y -2,5-dicarboxilicos, procedimiento para su preparacion, utilizacion de las mismas, asi como medicamentos a base de estos compuestos.
ES2053778T3 (es) Procedimiento para la obtencion de derivados del tiazol.
YU22996A (sh) Novi derivati arilglicinamida postupci za njihovo pripremanje i farmaceutski preparati koji sadrže ova jedinjenja
MX9202996A (es) Diazabiciclo-(3-3-1)nonanos.
AR009938A1 (es) Nuevos derivados de arilglicinamida, procedimientos para su preparacion y composiciones farmaceuticas que contienen estos compuestos
ES2059804T3 (es) Procedimiento de preparacion de eteres de oxima de propenona.
ES2040879T3 (es) Procedimiento de preparacion de derivados pirimidinilaminicos de piperidina.
ES2062706T3 (es) Nuevos derivados de amino-metil-piperidina su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2061580T3 (es) Compuestos de 3,7-diazabiciclo(3,3,1)nonano, asi como procedimiento para su preparacion y medicamentos que contienen estos compuestos.
ES2124698T3 (es) Cefalosporinas que contienen en posicion 3 un radical propenilo sustituido con un amonio cuaternario, su procedimiento de preparacion, su uso como medicamentos, composiciones que las contienen y productos intermedios.
AR001838A1 (es) Derivados de azacicloal canos utiles para el tratamiento de la obesidad diabetes e hiperglucemia procedimiento para prepararlos composiciones farmacéuticas que los contienen y aplicación de dichos derivados en la preparación de dichas composiciones
EA200300044A1 (ru) Новые замещенные фталиды, способ их получения и содержащие их фармацевтические композиции
ES2073393T3 (es) Derivados de acidos 2,4- y 2,5-dicarboxilicos, procedimiento para su preparacion, utilizacion de los mismos asi como medicamentos a base de estos compuestos.
ES2172376B1 (es) Nuevos derivados de isoquinoleinas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 264081

Country of ref document: ES