EG23929A - Isoxazolines derivatives and their use as antidepressants - Google Patents

Isoxazolines derivatives and their use as antidepressants

Info

Publication number
EG23929A
EG23929A EG20020197A EG20020197A EG23929A EG 23929 A EG23929 A EG 23929A EG 20020197 A EG20020197 A EG 20020197A EG 20020197 A EG20020197 A EG 20020197A EG 23929 A EG23929 A EG 23929A
Authority
EG
Egypt
Prior art keywords
antidepressants
isoxazolines
derivatives
isoxazolines derivatives
Prior art date
Application number
EG20020197A
Other languages
English (en)
Inventor
Jose I Andres-Gil
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of EG23929A publication Critical patent/EG23929A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EG20020197A 2001-02-21 2002-02-19 Isoxazolines derivatives and their use as antidepressants EG23929A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05

Publications (1)

Publication Number Publication Date
EG23929A true EG23929A (en) 2008-01-14

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
EG20020197A EG23929A (en) 2001-02-21 2002-02-19 Isoxazolines derivatives and their use as antidepressants

Country Status (32)

Country Link
US (1) US7169786B2 (da)
EP (1) EP1368358B1 (da)
JP (1) JP3953424B2 (da)
KR (1) KR100848898B1 (da)
CN (1) CN100400540C (da)
AR (1) AR035685A1 (da)
AT (1) ATE337322T1 (da)
AU (1) AU2002244717B2 (da)
BG (1) BG107984A (da)
BR (1) BR0207433A (da)
CA (1) CA2437505C (da)
CY (1) CY1106448T1 (da)
CZ (1) CZ20032515A3 (da)
DE (1) DE60214138T2 (da)
DK (1) DK1368358T3 (da)
EA (1) EA006747B1 (da)
EE (1) EE200300398A (da)
EG (1) EG23929A (da)
ES (1) ES2271230T3 (da)
HR (1) HRP20030647A2 (da)
HU (1) HUP0303270A3 (da)
IL (2) IL157470A0 (da)
MX (1) MXPA03007432A (da)
MY (1) MY137836A (da)
NO (1) NO20033700L (da)
NZ (1) NZ526741A (da)
PL (1) PL208593B1 (da)
PT (1) PT1368358E (da)
SI (1) SI1368358T1 (da)
SK (1) SK11612003A3 (da)
TW (1) TWI257392B (da)
WO (1) WO2002066484A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
BR0308309A (pt) * 2002-04-02 2004-12-28 Janssen Pharmaceutica Nv Derivados de isoxazolina amino substituìdo e seu uso como antidepressivos
TW200409777A (en) * 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
ATE456568T1 (de) * 2002-08-15 2010-02-15 Janssen Pharmaceutica Nv Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva
DE60319388T2 (de) * 2002-08-21 2009-02-19 Janssen Pharmaceutica N.V. C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva
AU2004218115A1 (en) * 2003-03-07 2004-09-16 Astellas Pharma Inc. Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl
EP1905774B1 (en) * 2003-09-17 2013-02-20 Janssen Pharmaceutica N.V. Fused heterocyclic compounds as serotonin receptor modulators
US7402680B2 (en) * 2003-09-17 2008-07-22 Janssen Pharmaceutica, N.V. Fused heterocyclic compounds
ATE443707T1 (de) * 2004-11-26 2009-10-15 Janssen Pharmaceutica Nv Isoxazolin-indol-derivate mit verbesserter antipsychotischer und anxiolytischer aktivität
MX2009009447A (es) * 2007-03-09 2009-09-14 Sanofi Aventis Dihidro y tetrahidro oxazolopirimidinonas sustituidas, preparacion y uso de las mismas.
WO2008154442A1 (en) * 2007-06-08 2008-12-18 Helicon Therapeutics, Inc. Therapeutic pyrazoloquinoline urea derivatives
JP2011507835A (ja) 2007-12-21 2011-03-10 アンドレイ・アレクサンドロビッチ・イワシェンコ α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68906340T2 (de) 1988-09-19 1993-08-12 Akzo Nv Tetrahydronaphthalin und indan-derivate.
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
EP0892804B1 (en) * 1996-04-12 2002-08-28 Janssen Pharmaceutica N.V. Isoxazolidine derivatives
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
CA2346396C (en) * 1998-10-09 2009-04-28 Janssen Pharmaceutica N.V. 4,5-dihydro-isoxazole derivatives and their pharmaceutical use

Also Published As

Publication number Publication date
IL157470A0 (en) 2004-03-28
AR035685A1 (es) 2004-06-23
CA2437505A1 (en) 2002-08-29
CN1492871A (zh) 2004-04-28
EE200300398A (et) 2003-12-15
DE60214138D1 (de) 2006-10-05
NZ526741A (en) 2004-04-30
CZ20032515A3 (cs) 2003-12-17
PT1368358E (pt) 2007-01-31
HRP20030647A2 (en) 2005-06-30
WO2002066484A1 (en) 2002-08-29
EA200300915A1 (ru) 2004-06-24
US20040122037A1 (en) 2004-06-24
NO20033700L (no) 2003-10-21
BG107984A (bg) 2004-09-30
JP3953424B2 (ja) 2007-08-08
HUP0303270A2 (hu) 2004-01-28
ES2271230T3 (es) 2007-04-16
DK1368358T3 (da) 2007-01-02
AU2002244717B2 (en) 2007-07-19
EP1368358A1 (en) 2003-12-10
US7169786B2 (en) 2007-01-30
DE60214138T2 (de) 2007-03-29
PL363264A1 (en) 2004-11-15
HUP0303270A3 (en) 2007-03-28
PL208593B1 (pl) 2011-05-31
SI1368358T1 (sl) 2007-02-28
TWI257392B (en) 2006-07-01
EA006747B1 (ru) 2006-04-28
HK1065537A1 (zh) 2005-02-25
MXPA03007432A (es) 2003-11-18
ATE337322T1 (de) 2006-09-15
KR100848898B1 (ko) 2008-07-29
NO20033700D0 (no) 2003-08-20
IL157470A (en) 2008-07-08
CA2437505C (en) 2010-02-09
SK11612003A3 (sk) 2004-04-06
KR20030076590A (ko) 2003-09-26
MY137836A (en) 2009-03-31
CN100400540C (zh) 2008-07-09
EP1368358B1 (en) 2006-08-23
JP2004518748A (ja) 2004-06-24
BR0207433A (pt) 2004-06-01
CY1106448T1 (el) 2011-10-12

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